Figure 2.
Fig. 2. Overall protein fold and peptide binding groove
of HLA-B*2705·m9 and B*2709·m9. A, ribbon
representation of HLA-B*2709·m9 (HC in blue, [2]m in
green, peptide as ball-and-stick model in red, and disulfide
bridges and Cys67 in yellow). B, superimposition of the peptide
binding grooves of B*2705·m9, B*2709·m9, and
B*2705·ARA[7] (PDB entry 1hsa). Because the binding
grooves are highly similar, only the backbone of the HC of
B*2705·m9 is depicted (ribbon representation). Peptides
are shown as C[ ]traces,
m9 from B*2705 in blue, m9 from B*2709 in cyan, and ARA[7] in
yellow.
[2]m in
green, peptide as ball-and-stick model in red, and disulfide
bridges and Cys67 in yellow). B, superimposition of the peptide
binding grooves of B*2705·m9, B*2709·m9, and
B*2705·ARA[7] (PDB entry 1hsa). Because the binding
grooves are highly similar, only the backbone of the HC of
B*2705·m9 is depicted (ribbon representation). Peptides
are shown as C[ 
]traces,
m9 from B*2705 in blue, m9 from B*2709 in cyan, and ARA[7] in
yellow.