Figure 1 - full size

Figure 1.
Fig. 1. Ribbon superpositions of the variable regions of the germline Fab-hapten complex (light purple) and mature Fab-hapten complex (dark red). The aliphatic linker used to conjugate the hapten to the carrier protein can be seen extending toward the top of^ the figure. The side chains of the somatic mutation sites are^ indicated in light green (germ line) and dark green (mature) (SerL30 Asn, SerL34 Gly, AspL55 His, GluH42 Lys, GlyH55 Val, AsnH56 Asp, GlyH65 Asp, AsnH76 Lys, Ala^H78 Thr).