Figure 1 - full size

Figure 1.
FIGURE 1. The crystal structure of rTp34. A, monomeric structure. A ribbon model of the crystal structure is shown with secondary structural elements colored purple for -strands, green for the 3[10] helix, and blue for regions with no regular secondary structure. Letters of the elements are indicated, as are the N and C termini of the model. B, dimeric structure. The bottom monomer is colored as in A and is rotated about 90° to the left around the vertical axis. The other monomer is colored tan. Residues that form inner-sphere contacts with the two interdimeric Zn^2+ ions (orange spheres) are shown as balls and sticks and are colored according to the monomer from which they originate; purple for the bottom monomer, and tan for the top. The liganding interactions are shown as black dashed lines.