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Figure 1.
The G1 tail of Hantaviruses, Nairoviruses, and
Orthobunyaviruses (genera of Bunyaviridae) contains a
cysteine/histidine-rich region with two CCHC arrays. Structure
determination of the Andes virus dual CCHC-region revealed a
novel zinc finger domain. Shown are the secondary structures
(α-helices and β-strands), zinc-coordinating residues
(blocked), the two CCHC motifs (boxed), conserved residues
(gray), and residue numbers for the Andes virus G1 sequence.
Sequence alignment was generated using CLUSTALW and formatted
with ESPript 2.2 (53).
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