Figure 1 - full size

Figure 1. Fig. 1. Structure of the clamp-loader complex. (A) Two views of the structure of the ATP S complex. The A subunit is , which is primarily responsible for opening the clamp. The ATP-binding subunits, , are labeled B-D. The E subunit is '. (B) Schematic diagram showing a suggested mechanism for clamp binding by the clamp-loader complex. Illustrations of protein structures were generated by using PYMOL (43).