Figure 1.
Figure 1 Structure of EF -CaM complex. (A) Ribbon diagram of EF
in complex with CaM and that of LF. Catalytic core domain,
helical domain, N-terminal PABD, and C-terminal PABD of EF are
colored in green, yellow, blue, and purple, respectively, and
CaM in red. N-terminal PABD, C-terminal PABD, and protease
domain of LF are in blue, purple and green, respectively. (B)
Comparison of PABDs of EF and LF. The similar secondary
structures of the N-terminal /
sandwich
of PABDs of EF and LF are depicted in blue and dark blue,
respectively, and those of the C-terminal five-helix domain of
PABD of EF and LF are colored in purple and magenta,
respectively. Five loops, L1 -L5, which have significant
differences between EF-PABD and LF-PABD, are colored in cyan and
yellow, respectively. (C) Sequence alignment of PABD of EF and
LF. Identical sequences are colored in yellow and similar
sequences are in green.
/
sandwich
of PABDs of EF and LF are depicted in blue and dark blue,
respectively, and those of the C-terminal five-helix domain of
PABD of EF and LF are colored in purple and magenta,
respectively. Five loops, L1 -L5, which have significant
differences between EF-PABD and LF-PABD, are colored in cyan and
yellow, respectively. (C) Sequence alignment of PABD of EF and
LF. Identical sequences are colored in yellow and similar
sequences are in green.