Figure 1 - full size

Figure 1.
Fig. 1. A: The GluR2-S1S2J construct, comprising the ligand-binding core of the AMPA-receptor subunit GluR2, is composed of segments S1 and S2, joined by a linker (dashed line). The two domains D1 and D2 are shown in yellow and green, respectively. The amino-terminal domain is outlined as a red sphere, and integral membrane parts are blue. B: The chemical structures of (S)-Des-Me-AMPA, (S)-AMPA and (S)-2-Me-Tet-AMPA.