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Figure 1.
Figure 1. The nidogen G2 structure. a, Stereo view of the
structure with the EGF-like domain in green and the  -barrel
domain in cyan. -strands
are labeled a -b in the EGF-like domain and A -K in the -barrel
domain. The  -helices
1 -3 are in red and disulfide bridges in yellow. To facilitate
the tracing of the polypeptide chain disordered segments
(residues 357 -366, 374 -380, 565 -570 and 588 -595) have been
included in arbitrary but stereochemically sensible
conformations and are shown in light gray. b, Topology diagram
of the -barrel
domain. The barrel is closed by the parallel interaction of
strands A and F. c, Stereo view of a portion of the experimental
electron density map after solvent flattening at 2.8 Å
resolution. The final model is superimposed on the map. Shown
are -strands
D, E and F. Figs 1a,c, 2 and 4 were made with BOBSCRIPT35 and
RASTER3D^36.
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