|
Figure 1.
Figure 1 Domain organization of mouse perlecan (Noonan et al.,
1991) and nidogen-1 (Mann et al., 1989). HS, heparan sulfate
oligosaccharide chains; SEA, domain found in sea urchin sperm
protein, enterokinase, agrin; LA, LDL receptor type A; IG,
immunoglobulin-like; L4, laminin domain IV; LE, laminin type
epidermal growth factor-like; LG, laminin G-like; EG, epidermal
growth factor-like; TY, thyroglobulin-like; G1 -3, nidogen
globular domains. The double-headed arrow indicates the
high-affinity interaction between nidogen-1 G2 (in cyan, with
the preceding EG domain in green) and perlecan IG3 (in magenta).
|
