_EC 6.3.2.11 Carnosine synthase. 0 PDB entries  
EC 6.-.-.- Ligases. [1,575 PDB entries]
EC 6.3.-.- Forming carbon-nitrogen bonds. [797 PDB entries]
EC 6.3.2.- Acid--amino-acid ligases (peptide synthases). [330 PDB entries]
EC 6.3.2.11 Carnosine synthase. [-]    

Reaction: Atp + L-histidine + beta-alanine = adp + phosphate + carnosine.
 


ATP
+
L-histidine
+
beta-alanine
=
ADP
+
phosphate
+
carnosine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Carnosine synthetase.
Comments: This enzyme was thought to form Amp, but studies with highly purified enzyme proved that it forms Adp. Carnosine is a dipeptide that is present at high concentrations in skeletal muscle and the olfactory bulb of vertebrates. It is also found in the skeletal muscle of some invertebrates. The enzyme can also catalyze the formation of homocarnosine from 4-aminobutyrate and L-histidine, with much lower activity.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.6.3.2.11