_EC 5.99.1.3 Dna topoisomerase (ATP-hydrolyzing). 134 PDB entries  
EC 5.-.-.- Isomerases. [2,270 PDB entries]
EC 5.99.-.- Other isomerases. [192 PDB entries]
EC 5.99.1.- Sole sub-subclass for isomerases that do not belong in the other [192 PDB entries]
EC 5.99.1.3 Dna topoisomerase (ATP-hydrolyzing). [134 PDB entries]    
1ab4

Reaction: ATP-dependent breakage, passage and rejoining of double-stranded Dna.
Other name(s): Dna gyrase. Dna topoisomerase ii. Type Ii dna topoisomerase.
Comments: Can introduce negative superhelical turns into double-stranded circular Dna. One unit has nicking-closing activity, and another catalyzes super- twisting and hydrolysis of Atp (cf. Ec 5.99.1.2).
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 134 PDB entries in enzyme class E.C.5.99.1.3

  PDB code Protein
1ab4
59kda fragment of gyrase a from e. Coli
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (477 residues) CATH domains: 3.90.199.10 3.30.1360.40 1.10.268.10
1aj6
Novobiocin-resistant mutant (r136h) of the n-terminal 24 kda of DNA gyrase b complexed with novobiocin at 2.3 angstroms
Source: Escherichia coli. Organism_taxid: 562. Cellular_location: cytoplasm. Gene: gyrb. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: plasmid ptb382 encoding mutant derived from which encodes 24 kda subdomain (supplied by a. Maxwell, lei which in turn was derived from pag111 plasmid which encodes
Chain: A (194 residues) CATH domain: 3.30.565.10
1am2
Gyra intein from mycobacterium xenopi
Source: Mycobacterium xenopi. Organism_taxid: 1789. Gene: rtp. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (181 residues) CATH domain: 2.170.16.10
1bgw
Topoisomerase residues 410-1202,
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (680 residues) CATH domains: 3.30.1490.30 3.40.50.670 1.10.268.10 3.30.1360.40 3.90.199.10
1bjt
Topoisomerase ii residues 409-1201
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (679 residues) CATH domains: 3.30.1490.30 3.40.50.670 1.10.268.10 3.30.1360.40 3.90.199.10
1d3y
Structure of the DNA topoisomerase vi a subunit
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (289 residues) CATH domains: 1.10.10.10 3.40.1360.10
1ei1
Dimerization of e. Coli DNA gyrase b provides a structural m for activating the atpase catalytic center
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562. Pn43-y5s). Other_details: pn43-y5s (tac promoter, beta lactamase gene, gene, pbr322 background)
Chains: A, B (391 residues) CATH domains: 3.30.565.10 3.30.230.10
1gku
Reverse gyrase from archaeoglobus fulgidus
Source: Archaeoglobus fulgidus. Organism_taxid: 224325. Strain: vc-16. Atcc: 49558. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: german collection of microorganisms (dsmz)
Chain: B (1011 residues) CATH domains: 2.20.20.30 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
1gl9
Archaeoglobus fulgidus reverse gyrase complexed with adpnp
Source: Archaeoglobus fulgidus. Organism_taxid: 224325. Strain: vc-16. Atcc: 49558. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: german collection of microorganisms (dsmz)
Chains: B, C (1020 residues) CATH domains: 2.20.20.30 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
1kij
Crystal structure of the 43k atpase domain of thermus thermo gyrase b in complex with novobiocin
Source: Thermus thermophilus. Organism_taxid: 274. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (384 residues) CATH domains: 3.30.565.10 3.30.230.10
1kzn
Crystal structure of e. Coli 24kda domain in complex with clorobiocin
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (186 residues) CATH domain: 3.30.565.10
1lwz
Human DNA topoisomerase ii, alpha isozyme
Source: Homo sapiens. Human
Chain: A (779 residues)
1mu5
Structure of topoisomerase subunit
Source: Sulfolobus shibatae. Organism_taxid: 2286. Gene: top6b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (460 residues) CATH domains: 3.30.565.10 1.10.8.50 3.30.230.10
1mx0
Structure of topoisomerase subunit
Source: Sulfolobus shibatae. Organism_taxid: 2286. Gene: top6b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (461 residues) CATH domains: 3.30.565.10 1.10.8.50 3.30.230.10
1pvg
Crystal structure of the atpase region of saccharomyces cere topoisomerase ii
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: top2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (378 residues) CATH domains: 3.30.565.10 3.30.230.10
1q1d
Crystal structure of the atpase region of saccharomyces cerevisiae topoisomerase ii bound to icrf-187 (dexrazoxane)
Source: Saccharomyces cerevisiae. Yeast. Gene: top2. Expressed in: escherichia coli.
Chains: A, B (382 residues) CATH domains: 3.30.565.10 3.30.230.10
1qzr
Crystal structure of the atpase region of saccharomyces cere topoisomerase ii bound to icrf-187 (dexrazoxane)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: top2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (382 residues) CATH domains: 3.30.565.10 3.30.230.10
1s14
Crystal structure of escherichia coli topoisomerase iv pare subunit
Source: Escherichia coli. Organism_taxid: 562. Gene: pare, nfxd, b3030. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (168 residues) CATH domain: 3.30.565.10
1s16
Crystal structure of e. Coli topoisomerase iv pare 43kda sub complexed with adpnp
Source: Escherichia coli. Organism_taxid: 562. Gene: pare, nfxd, b3030. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (380 residues) CATH domains: 3.30.565.10 3.30.230.10
1suu
Structure of DNA gyrase a c-terminal domain
Source: Borrelia burgdorferi. Lyme disease spirochete. Organism_taxid: 139. Gene: gyra, bb0435. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (293 residues) CATH domain: 2.120.10.90
1x75
Ccdb:gyra14 complex
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B (128 residues) CATH domain: 1.10.268.10
1z59
Topoisomerase vi-b, adp-bound monomer form
Source: Sulfolobus shibatae. Organism_taxid: 2286. Gene: top6b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (462 residues) CATH domains: 3.30.565.10 1.10.8.50 3.30.230.10
1z5a
Topoisomerase vi-b, adp-bound dimer form
Source: Sulfolobus shibatae. Organism_taxid: 2286. Gene: top6b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (466 residues) CATH domains: 3.30.565.10 1.10.8.50 3.30.230.10
1z5b
Topoisomerase vi-b, adp alf4- bound dimer form
Source: Sulfolobus shibatae. Organism_taxid: 2286. Gene: top6b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (466 residues) CATH domains: 3.30.565.10 1.10.8.50 3.30.230.10
1z5c
Topoisomerase vi-b, adp pi bound dimer form
Source: Sulfolobus shibatae. Organism_taxid: 2286. Gene: top6b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (466 residues) CATH domains: 3.30.565.10 1.10.8.50 3.30.230.10
1zi0
A superhelical spiral in escherichia coli DNA gyrase a c- terminal domain imparts unidirectional supercoiling bias
Source: Escherichia coli. Organism_taxid: 562. Gene: gyra, hisw, nala, pard. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (287 residues) CATH domain: 2.120.10.90
1zvt
Structure of the e. Coli parc c-terminal domain
Source: Escherichia coli. Organism_taxid: 562. Gene: parc. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (245 residues)
1zvu
Structure of the full-length e. Coli parc subunit
Source: Escherichia coli. Organism_taxid: 562. Gene: parc. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (685 residues) CATH domains: Unassigned Unassigned 1.10.268.10
1zxm
Human topo iia atpase/amp-pnp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: top2a, top2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (373 residues) CATH domains: 3.30.565.10 3.30.230.10
1zxn
Human DNA topoisomerase iia atpase/adp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: top2a, top2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (366 residues) CATH domains: 3.30.565.10 3.30.230.10
2hkj
Topoisomerase vi-b bound to radicicol
Source: Sulfolobus shibatae. Organism_taxid: 2286. Gene: top6b. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (461 residues) CATH domains: 3.30.565.10 1.10.8.50 3.30.230.10
2inr
Crystal structure of a 59 kda fragment of topoisomerase iv s (grla) from staphylococcus aureus
Source: Staphylococcus aureus. Organism_taxid: 1280. Strain: rn4220. Gene: parc. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (442 residues) CATH domain: Unassigned
2nov
Breakage-reunion domain of s.Pneumoniae topo iv: crystal structure of a gram-positive quinolone target
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: 7785. Gene: parc. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (440 residues) CATH domain: Unassigned
2q2e
Crystal structure of the topoisomerase vi holoenzyme from methanosarcina mazei
Source: Methanosarcina mazei. Organism_taxid: 2209. Gene: top6a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: top6b.
Chains: A, B (315 residues) CATH domains: Unassigned 3.40.1360.10
2rgr
Topoisomerase iia bound to g-segment DNA
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: top2, tor3. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Synthetic: yes. Synthetic: yes
Chain: A (721 residues) CATH domains: 3.40.50.670 3.30.1490.30 3.90.199.10 3.30.1360.40 1.10.268.10
2wl2
Crystal structure of n-terminal domain of gyra with the antibiotic simocyclinone d8
Source: Escherichia coli. Organism_taxid: 562. Strain: jmtaca. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: plyss.
Chains: A, B (496 residues) CATH domain: 3.90.199.10
2xco
The 3.1a crystal structure of the catalytic core (b'a' region) of staphylococcus aureus DNA gyrase
Source: Staphylococcus aureus. Organism_taxid: 158879. Strain: n315. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (638 residues) CATH domains: Unassigned 3.90.199.10 3.30.1360.40
2xcq
The 2.98a crystal structure of the catalytic core (b'a' region) of staphylococcus aureus DNA gyrase
Source: Staphylococcus aureus. Organism_taxid: 158879. Strain: n315. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (653 residues) CATH domains: Unassigned 3.90.199.10
2xcr
The 3.5a crystal structure of the catalytic core (b'a' region) of staphylococcus aureus DNA gyrase complexed with gsk299423 and DNA
Source: Staphylococcus aureus. Organism_taxid: 1280. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Organism_taxid: 32630
Chains: B, D, S, U (718 residues) CATH domains: Unassigned 3.90.199.10
2xcs
The 2.1a crystal structure of s. Aureus gyrase complex with and DNA
Source: Staphylococcus aureus. Organism_taxid: 158879. Strain: n315. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630
Chains: B, D (672 residues) CATH domains: Unassigned Unassigned
2xct
The twinned 3.35a structure of s. Aureus gyrase complex with ciprofloxacin and DNA
Source: Staphylococcus aureus. Organism_taxid: 158879. Strain: n315. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Organism_taxid: 32630
Chains: B, D, S, U (669 residues) CATH domains: Unassigned Unassigned
2xkj
Crystal structure of catalytic core of a. Baumannii topo iv (pare-parc fusion truncate)
Source: Acinetobacter baumannii. Organism_taxid: 470. Strain: eurofins medinet. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: E (721 residues) CATH domains: Unassigned Unassigned
2xkk
Crystal structure of moxifloxacin, DNA, and a. Baumannii top (pare-parc fusion truncate)
Source: Acinetobacter baumannii. Organism_taxid: 470. Strain: eurofins medinet. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Organism_taxid: 32630
Chains: A, C (692 residues) CATH domains: Unassigned Unassigned
2y3p
Crystal structure of n-terminal domain of gyra with the antibiotic simocyclinone d8
Source: Escherichia coli. Organism_taxid: 562. Strain: jmtaca. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: plyss.
Chains: A, B (496 residues) CATH domain: 3.90.199.10
2zbk
Crystal structure of an intact type ii DNA topoisomerase: insights into DNA transfer mechanisms
Source: Sulfolobus shibatae. Archaea. Organism_taxid: 2286. Gene: top6a. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: top6b.
Chains: A, B, C, D, E, F, G, H (347 residues) CATH domains: 1.10.10.10 3.40.1360.10
2zjt
Crystal structure of DNA gyrase b' domain sheds lights on th mechanism for t-segment navigation
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Strain: h37rv. Gene: gyrb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (185 residues) CATH domains: Unassigned Unassigned
3foe
Structural insight into the quinolone-DNA cleavage complex of type iia topoisomerases
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Gene: parc, sp_0855. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pare, sp_0852. Synthetic: yes. Synthetic: yes
Chains: A, B, C, D (432 residues) CATH domain: 3.90.199.10
3fof
Structural insight into the quinolone-DNA cleavage complex of type iia topoisomerases
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Gene: parc, sp_0855. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pare, sp_0852. Synthetic: yes. Synthetic: yes
Chains: A, B, C, D (435 residues) CATH domain: 3.90.199.10
3fv5
Crystal structure of e. Coli topoisomerase iv co-complexed with inhibitor
Source: Escherichia coli. Organism_taxid: 83333. Strain: k-12. Gene: pare, nfxd, b3030, jw2998. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (180 residues) CATH domain: 3.30.565.10
3g75
Crystal structure of staphylococcus aureus gyrase b co-compl 4-methyl-5-[3-(methylsulfanyl)-1h-pyrazol-5-yl]-2-thiophen- thiazole inhibitor
Source: Staphylococcus aureus. Organism_taxid: 1280. Gene: gyrb. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (184 residues) CATH domain: 3.30.565.10
3g7b
Staphylococcus aureus gyrase b co-complex with methyl ({5-[4 hydroxypiperidin-1-yl)-2-phenyl-1,3-thiazol-5-yl]-1h-pyrazo yl}methyl)carbamate inhibitor
Source: Staphylococcus aureus. Organism_taxid: 1280. Gene: gyrb. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (184 residues) CATH domain: 3.30.565.10
3g7e
Crystal structure of e. Coli gyrase b co-complexed with prop {[5-(4-piperidin-1-yl-2-pyridin-3-yl-1,3-thiazol-5-yl)-1h-p yl]methyl}carbamate inhibitor
Source: Escherichia coli. Organism_taxid: 562. Gene: ecs4634. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (203 residues) CATH domain: 3.30.565.10
3ifz
Crystal structure of the first part of the mycobacterium tub DNA gyrase reaction core: the breakage and reunion domain a resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: gyra, mt0006, mtcy10h4.04, rv0006. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (487 residues) CATH domain: Unassigned
3ig0
Crystal structure of the second part of the mycobacterium tu DNA gyrase reaction core: the toprim domain at 2.1 a resolu
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: hr37rv. Gene: gyrb, mt0005, mtcy10h4.03, rv0005. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (185 residues) CATH domains: Unassigned Unassigned
3ilw
Structure of DNA gyrase subunit a n-terminal domain
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: gyra, mt0006, mtcy10h4.04, rv0006. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (464 residues) CATH domain: Unassigned
3k9f
Detailed structural insight into the quinolone-DNA cleavage type iia topoisomerases
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: 7785. Gene: parc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pare. Synthetic: yes. Synthetic: yes
Chains: A, B, C, D (481 residues) CATH domain: Unassigned
3ksa
Detailed structural insight into the DNA cleavage complex of topoisomerases (cleaved form)
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: 7785. Gene: parc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pare. Synthetic: yes. Synthetic: yes
Chains: A, B, C, D (474 residues) CATH domain: Unassigned
3ksb
Detailed structural insight into the DNA cleavage complex of topoisomerases (re-sealed form)
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: 7785. Gene: parc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pare. Synthetic: yes. Synthetic: yes
Chains: A, B, C, D (471 residues) CATH domain: Unassigned
3ku8
Ccdbvfi:gyra14ec
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: gyrase. Expressed in: escherichia coli. Expression_system_taxid: 469008. Vibrio fischeri. Organism_taxid: 668. Gene: ccdb.
Chains: A, B (135 residues) CATH domain: 1.10.268.10
3kua
Ccdbvfi:gyra14vfi
Source: Vibrio fischeri. Organism_taxid: 312309. Strain: atcc 700601 / es114. Gene: gyrase. Expressed in: escherichia coli. Expression_system_taxid: 469008. Organism_taxid: 668. Gene: ccdb. Expression_system_taxid: 562.
Chain: A (143 residues) CATH domain: 1.10.268.10
3l4j
Topoisomerase ii-DNA cleavage complex, apo
Source: Saccharomyces cerevisiae. Brewer's yeast,lager beer yeast,yeast. Organism_taxid: 4932. Gene: n2244, top2, tor3, ynl088w. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Synthetic: yes. Synthetic: yes
Chain: A (722 residues) CATH domains: 3.40.50.670 3.30.1490.30 3.90.199.10 3.30.1360.40 1.10.268.10
3l4k
Topoisomerase ii-DNA cleavage complex, metal-bound
Source: Saccharomyces cerevisiae. Brewer's yeast,lager beer yeast,yeast. Organism_taxid: 4932. Gene: n2244, top2, tor3, ynl088w. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Synthetic: yes. Synthetic: yes
Chain: A (722 residues) CATH domains: 3.40.50.670 3.30.1490.30 3.90.199.10 3.30.1360.40 1.10.268.10
3l6v
Crystal structure of the xanthomonas campestris gyrase a c- terminal domain
Source: Xanthomonas campestris pv. Campestris. Organism_taxid: 340. Gene: gyra, xcc1574. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (313 residues) CATH domain: 2.120.10.90
3lnu
Crystal structure of pare subunit
Source: Xanthomonas oryzae pv. Oryzae. Organism_taxid: 291331. Strain: kacc10331. Gene: pare, xoo2969. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (344 residues) CATH domains: 3.30.565.10 3.30.230.10
3lps
Crystal structure of pare
Source: Xanthomonas oryzae pv. Oryzae. Organism_taxid: 291331. Strain: kacc10331. Gene: pare, xoo2969. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (347 residues) CATH domains: 3.30.565.10 3.30.230.10
3lpx
Crystal structure of gyra
Source: Colwellia psychrerythraea. Organism_taxid: 167879. Strain: 34h. Gene: gyra, cps_2331. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (462 residues) CATH domains: 3.90.199.10 3.30.1360.40 1.10.268.10
3ltn
Inhibitor-stabilized topoisomerase iv-DNA cleavage complex ( pneumoniae)
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: 7785. Gene: parc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pare. Synthetic: yes. Synthetic: yes
Chains: A, B, C, D (481 residues) CATH domain: Unassigned
3m4i
Crystal structure of the second part of the mycobacterium tu DNA gyrase reaction core: the toprim domain at 1.95 a resol
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Strain: hr37rv. Gene: gyrb, mt0005, mtcy10h4.03, rv0005. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (190 residues) CATH domains: Unassigned Unassigned
3no0
Aquifex aeolicus type iia topoisomerasE C-terminal domain
Source: Aquifex aeolicus. Organism_taxid: 224324. Strain: vf5. Gene: aq_980, gyra, parc. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C (276 residues) CATH domain: 2.120.10.90
3nuh
A domain insertion in e. Coli gyrb adopts a novel fold that critical role in gyrase function
Source: Escherichia coli. Organism_taxid: 83333. Strain: k-12. Gene: gyra. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: gyrb.
Chains: A, B (485 residues) CATH domain: 3.90.199.10
3p4x
Helicase domain of reverse gyrase from thermotoga maritima
Source: Thermotoga maritima. Organism_taxid: 2336. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (399 residues) CATH domains: 3.40.50.300 3.40.50.300
3p4y
Helicase domain of reverse gyrase from thermotoga maritima -
Source: Thermotoga maritima. Organism_taxid: 2336. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (407 residues) CATH domains: 3.40.50.300 3.40.50.300
3qx3
Human topoisomerase iibeta in complex with DNA and etoposide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: top2b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the oligonucleotide sequence 5'-agccgagctgca 3' was purchased from viogene..
Chains: A, B (671 residues) CATH domains: 3.40.50.670 3.90.199.10 3.30.1360.40 1.10.268.10
3rad
Quinolone(clinafloxacin)-DNA cleavage complex of type iv top from s. Pneumoniae
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: 7785. Gene: parc, sp_0855. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pare, sp_0852. Synthetic: yes. Synthetic: yes
Chains: A, B, C, D (482 residues) CATH domain: Unassigned
3rae
Quinolone(levofloxacin)-DNA cleavage complex of type iv topo from s. Pneumoniae
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: 7785. Gene: parc, sp_0855. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pare, sp_0852. Synthetic: yes. Synthetic: yes
Chains: A, B, C, D (482 residues) CATH domain: Unassigned
3raf
Quinazolinedione-DNA cleavage complex of type iv topoisomera pneumoniae
Source: Streptococcus pneumoniae. Organism_taxid: 1313. Strain: 7785. Gene: parc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: pare. Synthetic: yes. Synthetic: yes
Chains: A, B, C, D (482 residues) CATH domain: Unassigned
3ttz
Crystal structure of a topoisomerase atpase inhibitor
Source: Staphylococcus aureus. Organism_taxid: 1280. Gene: gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (194 residues) CATH domain: 3.30.565.10
3u2d
S. Aureus gyrb atpase domain in complex with small molecule
Source: Staphylococcus aureus. Organism_taxid: 1280. Gene: gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (194 residues) CATH domain: 3.30.565.10
3u2k
S. Aureus gyrb atpase domain in complex with a small molecul inhibitor
Source: Staphylococcus aureus. Organism_taxid: 1280. Gene: gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (194 residues) CATH domain: 3.30.565.10
3uc1
Mycobacterium tuberculosis gyrase type iia topoisomerasE C-t domain
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: gyra, mra_0006. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (300 residues) CATH domain: 2.120.10.90
3zkb
Crystal structure of the atpase region of mycobacterium tuberculosis gyrb with amppnp
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P (380 residues) CATH domains: 3.30.565.10 3.30.230.10
3zkd
Crystal structure of the atpase region of mycobacterium tuberculosis gyrb with amppnp
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta
Chains: A, B, C, D, E, F, G, H (377 residues) CATH domains: 3.30.565.10 3.30.230.10
3zm7
Crystal structure of the atpase region of mycobacterium tuberculosis gyrb with amppcp
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss
Chains: A, B, C, D, E, F (359 residues) CATH domains: 3.30.565.10 3.30.230.10
4b6c
Structure of the m. Smegmatis gyrb atpase domain in complex with an aminopyrazinamide
Source: Mycobacterium smegmatis. Organism_taxid: 1772
Chains: A, B (161 residues) CATH domain: 3.30.565.10
4bae
Optimisation of pyrroleamides as mycobacterial gyrb atpase inhibitors: structure activity relationship and in vivo efficacy in the mouse model of tuberculosis
Source: Mycobacterium smegmatis. Organism_taxid: 1772. Expressed in: escherichia coli,. Expression_system_taxid: 562.
Chains: A, B, C, D (184 residues) CATH domain: 3.30.565.10
4bul
Novel hydroxyl tricyclics (e.G. Gsk966587) as potent inhibitors of bacterial type iia topoisomerases
Source: Staphylococcus aureus, staphylococcus organism_taxid: 1280, 1280. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Organism_taxid: 32630
Chains: A, C (675 residues) CATH domains: Unassigned Unassigned
4ckk
Apo structure of 55 kda n-terminal domain of e. Coli DNA gyrase a subunit
Source: Escherichia coli. Organism_taxid: 562. Strain: jmtaca. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: plyss.
Chains: A, B, C, D (485 residues) CATH domain: 3.90.199.10
4ckl
Structure of 55 kda n-terminal domain of e. Coli DNA gyrase a subunit with simocyclinone d8 bound
Source: Escherichia coli. Organism_taxid: 562. Strain: jmtaca. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: plyss.
Chains: A, B (450 residues) CATH domain: 3.90.199.10
4ddq
Structural plasticity of the bacillus subtilis gyra homodime
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: gyra, cafb, nala, bsu00070. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (458 residues) CATH domains: 3.90.199.10 3.30.1360.40
4ddt
Thermotoga maritima reverse gyrase, c2 form 2
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (1102 residues) CATH domains: Unassigned 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
4ddu
Thermotoga maritima reverse gyrase, c2 form 1
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (1102 residues) CATH domains: Unassigned 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
4ddv
Thermotoga maritima reverse gyrase, triclinic form
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (1102 residues) CATH domains: Unassigned 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
4ddw
Thermotoga maritima reverse gyrase, c-centered orthorhombic
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (1102 residues) CATH domains: Unassigned 3.40.50.300 3.40.50.300 Unassigned 3.40.50.140 1.10.460.10 Unassigned 1.10.290.10
4ddx
Thermotoga maritima reverse gyrase, primitive monoclinic for
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: rgy, topr, tm_0173. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (1102 residues)
4duh
Crystal structure of 24 kda domain of e. Coli DNA gyrase b i with small molecule inhibitor
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: gyrb, acrb, himb, hisu, nalc, para, pcba, b3699, jw56 expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (195 residues) CATH domain: 3.30.565.10
4ely
Ccdbvfi:gyra14ec
Source: Shigella flexneri. Organism_taxid: 623. Strain: k12. Gene: gyra, gyrase, s2444, sf2311. Expressed in: escherichia coli. Expression_system_taxid: 469008. Aliivibrio fischeri. Organism_taxid: 668. Gene: ccdb.
Chains: A, B (135 residues) CATH domain: 1.10.268.10
4elz
Ccdbvfi:gyra14vfi
Source: Vibrio fischeri. Organism_taxid: 312309. Strain: atcc 700601 / es114. Gene: gyra, vf_1204. Expressed in: escherichia coli. Expression_system_taxid: 469008. Organism_taxid: 388396. Strain: mj11. Gene: ccdb, vfmj11_a0651.
Chains: A, B (143 residues) CATH domain: 1.10.268.10
4em7
Crystal structure of a topoisomerase atp inhibitor
Source: Streptococcus pneumoniae ga47373. Organism_taxid: 760835. Gene: pare, spar94_0831. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (193 residues) CATH domain: 3.30.565.10
4emv
Crystal structure of a topoisomerase atp inhibitor
Source: Streptococcus pneumoniae ga47373. Organism_taxid: 760835. Gene: pare, spar94_0831. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (196 residues) CATH domain: 3.30.565.10
4fm9
Human topoisomerase ii alpha bound to DNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: top2, top2a. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Chain: A (727 residues) CATH domains: 3.40.50.670 3.30.1490.30 3.90.199.10 3.30.1360.40 1.10.268.10
4g0u
Human topoisomerase iibeta in complex with DNA and amsacrine
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: top2b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic: yes
Chains: A, B (655 residues) CATH domains: 3.40.50.670 3.90.199.10 3.30.1360.40 1.10.268.10
4g0v
Human topoisomerase iibeta in complex with DNA and mitoxantr
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: top2b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic: yes
Chains: A, B (663 residues) CATH domains: 3.40.50.670 3.90.199.10 3.30.1360.40 1.10.268.10
4g0w
Human topoisomerase iibeta in complex with DNA and ametantro
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: top2b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Synthetic: yes
Chains: A, B (664 residues) CATH domains: 3.40.50.670 3.90.199.10 3.30.1360.40 1.10.268.10
4g3n
Mycobacterium tuberculosis gyrase type iia topoisomerasE C-t domain at 1.4 a resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: gyra, mt0006, mtct10h4.04, mtcy10h4.04, rv0006, rv006 expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (302 residues) CATH domain: 2.120.10.90
4gee
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic activity.
Source: Enterococcus faecalis. Organism_taxid: 226185. Strain: atcc 700802 / v583. Gene: gyrb, ef_0005. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (193 residues) CATH domain: 3.30.565.10
4gfh
Topoisomerase ii-DNA-amppnp complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: top2, tor3, ynl088w, n2244. Synthetic: yes. Synthetic: yes
Chains: A, F (1103 residues)
4gfn
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic
Source: Enterococcus faecalis. Organism_taxid: 226185. Strain: atcc 700802 / v583. Gene: ef_0005, gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (193 residues) CATH domain: 3.30.565.10
4ggl
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic activity
Source: Enterococcus faecalis. Organism_taxid: 226185. Strain: atcc 700802 / v583. Gene: ef_0005, gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (193 residues) CATH domain: 3.30.565.10
4hxw
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic activity.
Source: Enterococcus faecalis. Organism_taxid: 226185. Strain: atcc 700802 / v583. Gene: ef_0005, gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (191 residues) CATH domain: 3.30.565.10
4hxz
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic activity.
Source: Francisella tularensis subsp. Holarcti organism_taxid: 376619. Strain: lvs. Gene: DNA topoisomerase iv subunit b pare, ftl_1726. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (366 residues) CATH domains: 3.30.565.10 3.30.230.10
4hy1
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic activity.
Source: Francisella tularensis subsp. Holarcti organism_taxid: 376619. Strain: lvs. Gene: DNA topoisomerase iv subunit b pare, ftl_1726. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (360 residues) CATH domains: 3.30.565.10 3.30.230.10
4hym
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic activity.
Source: Francisella tularensis subsp. Holarcti organism_taxid: 376619. Strain: lvs. Gene: ftl_1726. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (361 residues) CATH domains: 3.30.565.10 3.30.230.10
4hyp
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic activity.
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: acrb, b3699, gyrb, himb, hisu, jw5625, nalc. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (194 residues) CATH domain: 3.30.565.10
4hz0
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic activity.
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: b3030, DNA topoisomerase iv subunit b pare, jw2998, n pare. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (201 residues) CATH domain: 3.30.565.10
4hz5
Pyrrolopyrimidine inhibitors of DNA gyrase b and topoisomera part i: structure guided discovery and optimization of dual agents with potent, broad-spectrum enzymatic activity
Source: Enterococcus faecalis. Organism_taxid: 226185. Strain: atcc 700802 / v583. Gene: pare, ef_1615. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, J (191 residues) CATH domain: 3.30.565.10
4i3h
A three-gate structure of topoisomerase iv from streptococcu pneumoniae
Source: Synthetic: yes. Streptococcus pneumoniae. Organism_taxid: 170187. Strain: tigr4. Atcc: baa-334. Gene: pare, parc. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (1037 residues) CATH domains: 3.30.565.10 3.30.230.10
4j3n
Human topoisomerase iibeta in complex with DNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: top2b. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the oligonucleotide sequence 5'-agccgagctgca 3' was ordered from viogene..
Chains: A, B (666 residues) CATH domains: 3.40.50.670 3.90.199.10 3.30.1360.40 1.10.268.10
4juo
A low-resolution three-gate structure of topoisomerase iv fr streptococcus pneumoniae in space group h32
Source: Streptococcus pneumoniae. Organism_taxid: 170187. Strain: atcc baa-334 / tigr4. Gene: parc, sp_0855. Expressed in: escherichia coli. Expression_system_taxid: 562. Streptococcus pneumoniae serotype 4. Gene: pare. Synthetic: yes.
Chains: A, C (479 residues)
4k4o
The DNA gyrase b atp binding domain of enterococcus faecalis complex with a small molecule inhibitor
Source: Enterococcus faecalis. Organism_taxid: 226185. Strain: atcc 700802 / v583. Gene: ef_0005, gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (190 residues) CATH domain: 3.30.565.10
4kfg
The DNA gyrase b atp binding domain of escherichia coli in c with a small molecule inhibitor.
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: acrb, himb, hisu, nalc, para, pcba. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (189 residues) CATH domain: 3.30.565.10
4kqv
Topoisomerase iv atp binding domain of francisella tularensi complex with a small molecule inhibitor
Source: Francisella tularensis subsp. Holarcti organism_taxid: 376619. Strain: lvs. Gene: DNA topoisomerase iv subunit b pare, ftl_1726, ftl_17 expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (355 residues) CATH domain: 3.30.565.10
4ksg
DNA gyrase atp binding domain of enterococcus faecalis in co a small molecule inhibitor (4-[(1s,5r,6r)-6-amino-1-methyl- azabicyclo[3.2.0]hept-3-yl]-6-fluoro-n-methyl-2-[(2-methylp 5-yl)oxy]-9h-pyrimido[4,5-b]indol-8-amine)
Source: Enterococcus faecalis. Organism_taxid: 226185. Strain: atcc 700802 / v583. Gene: ef_0005, gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (190 residues) CATH domain: 3.30.565.10
4ksh
DNA gyrase atp binding domain of enterococcus faecalis in co a small molecule inhibitor (7-({4-[(3r)-3-aminopyrrolidin-1 chloro-6-ethyl-7h-pyrrolo[2,3-d]pyrimidin-2-yl}sulfanyl)-1, naphthyridin-1(4h)-ol)
Source: Enterococcus faecalis. Organism_taxid: 226185. Strain: atcc 700802 / v583. Gene: ef_0005, gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (193 residues) CATH domain: 3.30.565.10
4ktn
DNA gyrase atp binding domain of enterococcus faecalis in co a small molecule inhibitor ((3s)-1-[2-(pyrido[2,3-b]pyrazin ylsulfanyl)-9h-pyrimido[4,5-b]indol-4-yl]pyrrolidin-3-amine
Source: Enterococcus faecalis. Organism_taxid: 226185. Strain: atcc 700802 / v583. Gene: ef_0005, gyrb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (193 residues) CATH domain: 3.30.565.10
4lp0
Crystal structure of a topoisomerase atp inhibitor
Source: Streptococcus pneumoniae. Organism_taxid: 171101. Strain: atcc baa-255 / r6. Gene: pare, spr0756. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (192 residues) CATH domain: 3.30.565.10
4lpb
Crystal structure of a topoisomerase atpase inhibitor
Source: Streptococcus pneumoniae. Organism_taxid: 171101. Strain: atcc baa-255 / r6. Gene: pare, spr0756. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (193 residues) CATH domain: 3.30.565.10
4mb9
Structure of streptococcus pneumonia pare in complex with az
Source: Streptococcus pneumoniae. Organism_taxid: 760835. Strain: ga47373. Gene: spar94_0831. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (198 residues) CATH domain: 3.30.565.10
4mbc
Structure of streptococcus pneumonia pare in complex with az
Source: Streptococcus pneumoniae. Organism_taxid: 760835. Strain: ga47373. Gene: spar94_0831. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (193 residues) CATH domain: 3.30.565.10
4mn4
Structural basis for the mukb-topoisomerase iv interaction
Source: Escherichia coli. Organism_taxid: 511145. Strain: k-12 substr. Mg1655. Gene: parc. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: mukb.
Chains: A, B (246 residues) CATH domain: Unassigned
4mot
Structure of streptococcus pneumonia pare in complex with az
Source: Streptococcus pneumoniae. Organism_taxid: 171101. Strain: atcc baa-255 / r6. Gene: pare, spar94_0831, spr0756. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (193 residues) CATH domain: 3.30.565.10
4oz6
Structure of the branched intermediate in protein splicing
Source: Mycobacterium xenopi. Organism_taxid: 1789. Gene: gyra. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (172 residues) CATH domain: 2.170.16.10
4tma
Crystal structure of gyrase bound to its inhibitor yacg
Source: Escherichia coli. Organism_taxid: 1403831. Strain: k-12 substr. Mc4100. Gene: gyra, bn896_2003. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: gyrb, bn896_3389. Expression_system_taxid: 469008. Organism_taxid: 83333.
Chains: A, B, C, D, E, F, G, H (505 residues)
4urm
Crystal structure of staph gyraseb 24kda in complex with kibdelomycin
Source: Staphylococcus aureus. Organism_taxid: 1280. Expressed in: escherichia coli bl21(de3).
Chains: A, B, C, D (194 residues)
4uro
Crystal structure of staph gyraseb 24kda in complex with nov
Source: Staphylococcus aureus. Organism_taxid: 1280. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D (187 residues)