_EC 5.3.3.8 Dodecenoyl-CoA isomerase. 20 PDB entries  
EC 5.-.-.- Isomerases. [2,272 PDB entries]
EC 5.3.-.- Intramolecular oxidoreductases. [867 PDB entries]
EC 5.3.3.- Transposing C==C bonds. [220 PDB entries]
EC 5.3.3.8 Dodecenoyl-CoA isomerase. [20 PDB entries]    
1hno

Reaction: (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.
 


(3Z)-dodec-3-enoyl-CoA
=
(2E)-dodec-2-enoyl-CoA
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 3,2-trans-enoyl-CoA isomerase. Acetylene-allene isomerase. Delta(3),Delta(2)-enoyl-CoA isomerase. Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase. Dodecenoyl-CoA Delta-isomerase.
Comments: Also catalyzes the interconversion of 3-acetylenic fatty acyl thioesters and (+)-2,3-dienoyl fatty acyl thioesters, with fatty acid chain lengths C(6) to C(12).
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 20 PDB entries in enzyme class E.C.5.3.3.8

  PDB code Protein
1hno
Crystal structure of peroxisomal delta3-delta2-enoyl-coa iso from saccharomyces cerevisiae
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues) CATH domain: 3.90.226.10
1hnu
Crystal structure of peroxisomal delta3-delta2-enoyl-coa iso from saccharomyces cerevisiae
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues) CATH domain: 3.90.226.10
1k39
The structure of yeast delta3-delta2-enoyl-coa isomerase com with octanoyl-coa
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: eci1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (269 residues) CATH domain: 3.90.226.10
Bound ligand:   Het Group CO8 is 93.44% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
1pjh
Structural studies on delta3-delta2-enoyl-coa isomerase: the mode of assembly of the trimeric disks of the crotonase sup
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: eci1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (259 residues) CATH domain: 3.90.226.10
1sg4
Crystal structure of human mitochondrial delta3-delta2- enoyl-coa isomerase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: dci. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (249 residues) CATH domain: 3.90.226.10
Bound ligand:   Het Group CO8 is 93.00% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
1wdk
Fatty acid beta-oxidation multienzyme complex from pseudomonas fragi, form i (native2)
Source: Pseudomonas fragi. Organism_taxid: 296. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (708 residues) CATH domains: 3.90.226.10 3.40.50.720
Bound ligand:   Het Group ACO is 83.00% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
1wdl
Fatty acid beta-oxidation multienzyme complex from pseudomonas fragi, form ii (native4)
Source: Pseudomonas fragi. Organism_taxid: 296. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (715 residues) CATH domains: 3.90.226.10 3.40.50.720
Bound ligand:   Het Group ACO is 65.00% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
1wdm
Fatty acid beta-oxidation multienzyme complex from pseudomonas fragi, form i (native3)
Source: Pseudomonas fragi. Organism_taxid: 296. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (707 residues) CATH domains: 3.90.226.10 3.40.50.720
Bound ligand:   Het Group ACO is 83.00% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
1xx4
Crystal structure of rat mitochondrial 3,2-enoyl-coa
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: dci. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (254 residues) CATH domain: 3.90.226.10
1zcj
Crystal structure of 3-hydroxyacyl-coa dehydrogenase
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (459 residues) CATH domains: Unassigned 3.40.50.720 Unassigned 1.10.1040.10
2cqu
Solution structure of rsgi ruh-045, a human acyl-coa binding protein
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: cell-free protein synthesis (e.Coli)
Chain: A (116 residues) CATH domain: 1.20.80.10
2d3t
Fatty acid beta-oxidation multienzyme complex from pseudomonas fragi, form v
Source: Pseudomonas fragi. Organism_taxid: 296. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B (708 residues) CATH domains: 3.90.226.10 3.40.50.720
Bound ligand:   Het Group ACO is 83.00% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
2f6q
The crystal structure of human peroxisomal delta3, delta2 en isomerase (peci)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: peci. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (248 residues) CATH domains: 3.90.226.10 1.10.12.10
2wtb
Arabidopsis thaliana multifuctional protein, mfp2
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (676 residues) CATH domains: 3.90.226.10 3.40.50.720
2x58
The crystal structure of mfe1 liganded with coa
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (725 residues) CATH domains: 3.90.226.10 3.40.50.720
Bound ligand:   Het Group COA is 78.00% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
3zw8
Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) in apo form
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: peroxisome. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (725 residues) CATH domains: 3.90.226.10 3.40.50.720
3zw9
Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with (2s,3s)-3-hydroxy-2- methylbutanoyl-coa
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: peroxisome. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (723 residues) CATH domains: 3.90.226.10 3.40.50.720
Bound ligand:   Het Group T1G is 84.13% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
3zwa
Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with 3s-hydroxy-hexanoyl-coa
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: peroxisome. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (727 residues) CATH domains: 3.90.226.10 3.40.50.720
Bound ligand:   Het Group 3H9 is 88.71% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
3zwb
Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with 2trans-hexenoyl-coa
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: peroxisome. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (725 residues) CATH domains: 3.90.226.10 3.40.50.720
Bound ligand:   Het Group TC6 is 90.16% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA
3zwc
Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with 3s-hydroxy-decanoyl-coa
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: peroxisome. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (725 residues) CATH domains: 3.90.226.10 3.40.50.720
Bound ligand:   Het Group HSC is 95.16% similar to enzyme reactant (3Z)-dodec-3-enoyl-CoA