_EC 5.3.1.8 Mannose-6-phosphate isomerase. 10 PDB entries  
EC 5.-.-.- Isomerases. [2,270 PDB entries]
EC 5.3.-.- Intramolecular oxidoreductases. [862 PDB entries]
EC 5.3.1.- Interconverting aldoses and ketoses, and related compounds. [482 PDB entries]
EC 5.3.1.8 Mannose-6-phosphate isomerase. [10 PDB entries]    
1pmi

Pathway: GDP-L-Fucose and GDP-mannose Biosynthesis
Reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
 


D-mannose 6-phosphate
=
D-fructose 6-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Phosphohexoisomerase. Phosphohexomutase. Phosphomannoisomerase. Phosphomannose isomerase.
Cofactor(s): Zn(2+).
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 10 PDB entries in enzyme class E.C.5.3.1.8

  PDB code Protein
1pmi
Candida albicans phosphomannose isomerase
Source: Candida albicans. Organism_taxid: 5476
Chain: A (440 residues) CATH domains: 2.60.120.10 1.10.441.10 2.60.120.10
1qwr
Crystal structure analysis of the mannose 6-phosphate isomerase from bacillus subtilis
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: pmi or bsu35790. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (315 residues) CATH domains: 2.60.120.10 2.60.120.10
1tzb
Crystal structure of native phosphoglucose/phosphomannose is from pyrobaculum aerophilum
Source: Pyrobaculum aerophilum. Organism_taxid: 178306. Strain: str. Im2. Gene: pae1610. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (301 residues) CATH domains: 3.40.50.10490 3.40.50.10490
1tzc
Crystal structure of phosphoglucose/phosphomannose isomerase pyrobaculum aerophilum in complex with 5-phosphoarabinonate
Source: Pyrobaculum aerophilum. Organism_taxid: 178306. Strain: str. Im2. Gene: pae1610. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (301 residues) CATH domains: 3.40.50.10490 3.40.50.10490
Bound ligand:   Het Group PA5 is 82.35% similar to enzyme reactant D-mannose
1x9h
Crystal structure of phosphoglucose/phosphomannose isomerase pyrobaculum aerophilum in complex with fructose 6-phosphate
Source: Pyrobaculum aerophilum. Organism_taxid: 13773. Gene: pae1610. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (301 residues) CATH domains: 3.40.50.10490 3.40.50.10490
Bound ligand:   Het Group F6R corresponds to enzyme reactant D-mannose
1x9i
Crystal structure of crystal structure of phosphoglucose/phosphomannose phosphoglucose/phosphomannose from pyrobaculum aerophilum in complex with glucose 6-phosp
Source: Pyrobaculum aerophilum. Organism_taxid: 13773. Gene: pae1610. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (300 residues) CATH domains: 3.40.50.10490 3.40.50.10490
Bound ligand:   Het Group G6Q corresponds to enzyme reactant D-mannose
2wfp
Crystal structure of mannose 6-phosphate isomerase (apo form) from salmonella typhimurium
Source: Salmonella typhimurium. Organism_taxid: 99287. Strain: lt2. Atcc: 9150. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (389 residues) CATH domains: 2.60.120.10 2.60.120.10 1.10.441.10
3h1m
Crystal structure of mannose 6-phosphate isomerase (holo; zi
Source: Salmonella typhimurium. Organism_taxid: 602. Strain: lt2. Gene: aal20387, mana, pmi, stm1467. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (392 residues) CATH domains: 2.60.120.10 2.60.120.10 1.10.441.10
3h1w
Crystal structure of mannose 6-phosphate isomerase bound wit yttrium
Source: Salmonella typhimurium. Organism_taxid: 602. Strain: lt2. Gene: aal20387, mana, pmi, stm1467. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (390 residues) CATH domains: 2.60.120.10 2.60.120.10 1.10.441.10
3h1y
Crystal structure of mannose 6-phosphate isomerase from salmonella typhimurium bound to substrate (f6p)and metal atom (zn)
Source: Salmonella typhimurium. Organism_taxid: 602. Strain: lt2. Gene: aal20387, mana, pmi, stm1467. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (391 residues) CATH domains: 2.60.120.10 2.60.120.10 1.10.441.10
Bound ligand:   Het Group F6P corresponds to enzyme reactant D-mannose 6-phosphate