_EC 5.3.1.25 L-fucose isomerase. 7 PDB entries  
EC 5.-.-.- Isomerases. [2,271 PDB entries]
EC 5.3.-.- Intramolecular oxidoreductases. [866 PDB entries]
EC 5.3.1.- Interconverting aldoses and ketoses, and related compounds. [488 PDB entries]
EC 5.3.1.25 L-fucose isomerase. [7 PDB entries]    
1fui

Reaction: L-fucopyranose = L-fuculose.
 

L-fucopyranose
=
L-fuculose
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Cofactor(s): Mn(2+).
Comments: The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism. The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose. The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 7 PDB entries in enzyme class E.C.5.3.1.25

  PDB code Protein
1fui
L-fucose isomerase from escherichia coli
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Cell_line: jm105. Cellular_location: cytoplasm. Gene: fuci. Expressed in: escherichia coli k12. Expression_system_taxid: 83333. Expression_system_cell_line: jm105.
Chains: A, B, C, D, E, F (591 residues) CATH domains: 3.40.50.1070 3.40.275.10 3.20.14.10
Bound ligand:   Het Group FOC corresponds to enzyme reactant L-fucose
3a9r
X-ray structures of bacillus pallidus d-arabinose isomerasecomplex with (4r)-2-methylpentane-2,4-diol
Source: Geobacillus pallidus. Organism_taxid: 33936. Strain: 14a. Gene: dai. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (589 residues) CATH domains: 3.40.50.1070 3.40.275.10 3.20.14.10
3a9s
X-ray structure of bacillus pallidus d-arabinose isomerase complex with glycerol
Source: Geobacillus pallidus. Organism_taxid: 33936. Strain: 14a. Gene: dai. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (589 residues) CATH domains: 3.40.50.1070 3.40.275.10 3.20.14.10
3a9t
X-ray structure of bacillus pallidus d-arabinose isomerase complex with l-fucitol
Source: Geobacillus pallidus. Organism_taxid: 33936. Strain: 14a. Gene: dai. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (589 residues) CATH domains: 3.40.50.1070 3.40.275.10 3.20.14.10
4c20
L-fucose isomerase
Source: Streptococcus pneumoniae. Organism_taxid: 170187. Strain: tigr4. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (587 residues) CATH domains: 3.40.50.1070 3.40.275.10 3.20.14.10
4c21
L-fucose isomerase in complex with fucitol
Source: Streptococcus pneumoniae. Organism_taxid: 170187. Strain: tigr4. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (587 residues)
Bound ligand:   Het Group FOC corresponds to enzyme product L-fuculose
4c22
L-fucose isomerase in complex with fuculose
Source: Streptococcus pneumoniae. Organism_taxid: 170187. Strain: tigr4. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (587 residues)
Bound ligand:   Het Group FUC corresponds to enzyme product L-fuculose