_EC 5.3.1.1 Triose-phosphate isomerase. 181 PDB entries  
EC 5.-.-.- Isomerases. [2,469 PDB entries]
EC 5.3.-.- Intramolecular oxidoreductases. [929 PDB entries]
EC 5.3.1.- Interconverting aldoses and ketoses, and related compounds. [517 PDB entries]
EC 5.3.1.1 Triose-phosphate isomerase. [181 PDB entries]    
1ag1

Reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
 


D-glyceraldehyde 3-phosphate
=
glycerone phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Phosphotriose isomerase. Triose phosphoisomerase. Triosephosphate isomerase. Triosephosphate mutase.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 181 PDB entries in enzyme class E.C.5.3.1.1

  PDB code Protein
1ag1
Monohydrogen phosphate binding to trypanosomal triosephosphate isomerase
Source: Trypanosoma brucei. Organism_taxid: 5691. Organelle: glycosome
Chains: O, T (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PO4 is 50.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1amk
Leishmania mexicana triose phosphate isomerase
Source: Leishmania mexicana. Organism_taxid: 5665
Chain: A (250 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1aw1
Triosephosphate isomerase of vibrio marinus complexed with 2-phosphoglycolate
Source: Moritella marina. Organism_taxid: 90736. Atcc: 15382. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, D, E, G, H, J, K (255 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1aw2
Triosephosphate isomerase of vibrio marinus
Source: Moritella marina. Organism_taxid: 90736. Atcc: 15382. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, D, E, G, H, J, K (255 residues) CATH domain: 3.20.20.70
1b9b
Triosephosphate isomerase of thermotoga maritima
Source: Thermotoga maritima. Organism_taxid: 2336. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (252 residues) CATH domain: 3.20.20.70
1btm
Triosephosphate isomerase (tim) complexed with 2- phosphoglycolic acid
Source: Geobacillus stearothermophilus. Organism_taxid: 1422. Gene: potential. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (251 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1ci1
Crystal structure of triosephosphate isomerase from trypanos in hexane
Source: Trypanosoma cruzi. Organism_taxid: 5693. Strain: mexican ninoa strain. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (248 residues) CATH domain: 3.20.20.70
1dkw
Crystal structure of triose-phosphate isomerase with modified substrate binding site
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (238 residues) CATH domain: 3.20.20.70
1hg3
Crystal structure of tetrameric tim from pyrococcus woesei.
Source: Pyrococcus woesei. Organism_taxid: 2262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H (224 residues) CATH domain: 3.20.20.70
1hti
Crystal structure of recombinant human triosephosphate isomerase at 2.8 angstroms resolution. Triosephosphate isomerase related human genetic disorders and comparison with the trypanosomal enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606
Chains: A, B (248 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1i45
Yeast triosephosphate isomerase (mutant)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
1if2
X-ray structure of leishmania mexicana triosephosphate isome complexed with ipp
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (249 residues) CATH domain: 3.20.20.70
1iig
Structure of trypanosoma brucei brucei triosephosphate isomerase complexed with 3-phosphonopropionate
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (249 residues) CATH domain: 3.20.20.70
1iih
Structure of trypanosoma brucei brucei triosephosphate isomerase complexed with 3-phosphoglycerate
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 3PG is 90.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1klg
Crystal structure of hla-dr1/tpi(23-37, thr28-->ile mutant) complexed with staphylococcal enterotoxin c3 variant 3b2 (sec3-3b2)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: peptide synthesis. Staphylococcus aureus. Organism_taxid: 1280.
Chain: C (15 residues)
1klu
Crystal structure of hla-dr1/tpi(23-37) complexed with staphylococcal enterotoxin c3 variant 3b2 (sec3-3b2)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: peptide synthesis. Staphylococcus aureus. Organism_taxid: 1280.
Chain: C (15 residues)
1kv5
Structure of trypanosoma brucei brucei tim with the salt-bri forming residue arg191 mutated to ser
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1lnv
Structure of triosephosphate isomerase-salmonella typhimurium
Source: Salmonella typhimurium. Bacteria
Chain: A (255 residues)
1lyx
Plasmodium falciparum triosephosphate isomerase (pftim)- phosphoglycolate complex
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1lzo
Plasmodium falciparum triosephosphate isomerase- phosphoglycolate complex
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1m6j
Crystal structure of triosephosphate isomerase from entamoeba histolytica
Source: Entamoeba histolytica. Organism_taxid: 5759. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (260 residues) CATH domain: 3.20.20.70
1m7o
Plasmodium falciparum triosephosphate isomerase (pftim) compled to substrate analog 3-phosphoglycerate (3pg)
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 3PG is 90.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1m7p
Plasmodium falciparum triosephosphate isomerase (pftim) compled to substrate analog glycerol-3-phosphate (g3p).
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group G3H corresponds to enzyme reactant D-glyceraldehyde 3-phosphate
1ml1
Protein engineering with monomeric triosephosphate isomerase: the modelling and structure verification of a seven residue loop
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei. Cell_line: xl1-blue. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_cell_line: xl1-blue.
Chains: A, C, E, G, I, K (241 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1mo0
Structural genomics of caenorhabditis elegans: triose phosphate isomerase
Source: Caenorhabditis elegans. Organism_taxid: 6239. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
1mss
Large scale structural rearrangements of the front loops in monomerised triosephosphate isomerase, as deduced from the comparison of the structural properties of monotim and its point mutation variant monoss
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (242 residues) CATH domain: 3.20.20.70
1n55
0.83a resolution structure of the e65q mutant of leishmania triosephosphate isomerase complexed with 2-phosphoglycolate
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1ney
Triosephosphate isomerase in complex with dhap
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 13P corresponds to enzyme reactant D-glyceraldehyde 3-phosphate
1nf0
Triosephosphate isomerase in complex with dhap
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 13P corresponds to enzyme reactant D-glyceraldehyde 3-phosphate
1o5x
Plasmodium falciparum tim complexed to 2-phosphoglycerate
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 2PG is 61.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1qds
Superstable e65q mutant of leishmania mexicana triosephospha isomerase (tim)
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (250 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1r2r
Crystal structure of rabbit muscle triosephosphate isomerase
Source: Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Tissue: muscle
Chains: A, B, C, D (246 residues) CATH domain: 3.20.20.70
1r2s
Crystal structure of rabbit muscle triosephosphate isomerase
Source: Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Tissue: muscle
Chains: A, B, C, D (247 residues) CATH domain: 3.20.20.70
1r2t
Crystal structure of rabbit muscle triosephosphate isomerase
Source: Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Tissue: muscle
Chains: A, B (246 residues) CATH domain: 3.20.20.70
1spq
Understanding protein lids: structural analysis of active hi mutants in triosephosphate isomerase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (243 residues) CATH domain: 3.20.20.70
1sq7
Understanding protein lids: structural analysis of active hi mutants in triosephosphate isomerase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
1ssd
Understanding protein lids: structural analysis of active hi mutants in triosephosphate isomerase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
1ssg
Understanding protein lids: structural analysis of active hi mutants in triosephosphate isomerase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1su5
Understanding protein lids: structural analysis of active hi mutants in triosephosphate isomerase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1sux
Crystallographic analysis of the complex between triosephosphate isomerase from trypanosoma cruzi and 3-(2- benzothiazolylthio)-1-propanesulfonic acid
Source: Trypanosoma cruzi. Organism_taxid: 5693. Strain: mexican ninoa strain. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (250 residues) CATH domain: 3.20.20.70
1sw0
Triosephosphate isomerase from gallus gallus, loop 6 hinge m k174l, t175w
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1sw3
Triosephosphate isomerase from gallus gallus, loop 6 mutant
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1sw7
Triosephosphate isomerase from gallus gallus, loop 6 mutant t175s, a176s
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (245 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
1tcd
Trypanosoma cruzi triosephosphate isomerase
Source: Trypanosoma cruzi. Organism_taxid: 5693. Strain: mexican ninoa. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (248 residues) CATH domain: 3.20.20.70
1tim
Structure of triose phosphate isomerase from chicken muscle
Source: Gallus gallus. Chicken. Organism_taxid: 9031
Chains: A, B (247 residues) CATH domain: 3.20.20.70
1tmh
Modular mutagenesis of a tim-barrel enzyme: the crystal structure of a chimeric e. Coli tim having the eighth (beta-alpha)-unit replaced by the equivalent unit of chicken tim
Source: Escherichia coli. Organism_taxid: 562
Chains: A, B, C, D (254 residues) CATH domain: 3.20.20.70
1tpb
Offset of a catalytic lesion by a bound water soluble
Source: Gallus gallus. Chicken. Organism_taxid: 9031
Chains: 1, 2 (245 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.67% similar to enzyme reactant D-glyceraldehyde
1tpc
Offset of a catalytic lesion by a bound water soluble
Source: Gallus gallus. Chicken. Organism_taxid: 9031
Chains: 1, 2 (245 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.67% similar to enzyme reactant D-glyceraldehyde
1tpd
Structures of the "open" and "closed" state of trypanosomal triosephosphate isomerase, as observed in a new crystal for implications for the reaction mechanism
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (249 residues) CATH domain: 3.20.20.70
1tpe
Comparison of the structures and the crystal contacts of try triosephosphate isomerase in four different crystal forms
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chain: A (249 residues) CATH domain: 3.20.20.70
1tpf
Comparison of the structures and the crystal contacts of trypanosomal triosephosphate isomerase in four different crystal forms
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (250 residues) CATH domain: 3.20.20.70
1tph
1.8 angstroms crystal structure of wild type chicken triosephosphate isomerase-phosphoglycolohydroxamate complex
Source: Gallus gallus. Chicken. Organism_taxid: 9031
Chains: 1, 2 (245 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1tpu
S96p change is a second-site suppressor for h95n sluggish mu triosephosphate isomerase
Source: Gallus gallus. Chicken. Organism_taxid: 9031
Chains: A, B (245 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.67% similar to enzyme reactant D-glyceraldehyde
1tpv
S96p change is a second-site suppressor for h95n sluggish mu triosephosphate isomerase
Source: Gallus gallus. Chicken. Organism_taxid: 9031
Chains: A, B (245 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.67% similar to enzyme reactant D-glyceraldehyde
1tpw
Triosephosphate isomerase drinks water to keep healthy
Source: Gallus gallus. Chicken. Organism_taxid: 9031
Chains: A, B (245 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.67% similar to enzyme reactant D-glyceraldehyde
1trd
The influence of crystal packing on crystallographic binding a new crystal form of trypanosomal tim
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.67% similar to enzyme reactant D-glyceraldehyde
1tre
The structure of triosephosphate isomerase from escherichia coli determined at 2.6 angstrom resolution
Source: Escherichia coli. Organism_taxid: 562
Chains: A, B (255 residues) CATH domain: 3.20.20.70
1tri
The crystal structure of an engineered monomeric triosephosphate isomerase, monotim: the correct modelling of an eight-residue loop
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chain: A (239 residues) CATH domain: 3.20.20.70
1tsi
Structure of the complex between trypanosomal triosephosphate isomerase and n-hydroxy-4-phosphono- butanamide: binding at the active site despite an "open" flexible loop
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (249 residues) CATH domain: 3.20.20.70
1tti
Three new crystal structures of point mutation variants of monotim: conformational flexibility of loop-1,loop-4 and loop-8
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Other_details: escherichia coli strain xl1-blue used for the genetic manipulations
Chain: A (236 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1ttj
Three new crystal structures of point mutation variants of monotim: conformational flexibility of loop-1,loop-4 and loop-8
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chain: A (235 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1vga
Structures of unligated and inhibitor complexes of w168f mutant of triosephosphate isomerase from plasmodium falciparum
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (246 residues) CATH domain: 3.20.20.70
1vpe
Crystallographic analysis of phosphoglycerate kinase from the hyperthermophilic bacterium thermotoga maritima
Source: Thermotoga maritima. Organism_taxid: 2336. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (398 residues) CATH domains: 3.40.50.1260 3.40.50.1260
Bound ligand:   Het Group 3PG is 90.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1w0m
Triosephosphate isomerase from thermoproteus tenax
Source: Thermoproteus tenax. Organism_taxid: 2271. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G, H (226 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PO4 is 50.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1woa
Structure of the loop6 hinge mutant of plasmodium falciparum triosephosphate isomerase, w168f, complexed with glycerol-2-phosphate
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group G2H is 66.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
1wob
Structure of a loop6 hinge mutant of plasmodium falciparum triosephosphate isomerase, w168f, complexed to sulfate
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (246 residues) CATH domain: 3.20.20.70
1wyi
Human triosephosphate isomerase of new crystal form
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (248 residues) CATH domain: 3.20.20.70
1ydv
Triosephosphate isomerase (tim)
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (246 residues) CATH domain: 3.20.20.70
1ypi
Structure of yeast triosephosphate isomerase at 1.9- angstroms resolution
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932
Chains: A, B (247 residues) CATH domain: 3.20.20.70
1yya
Crystal structure of tt0473, putative triosephosphate isomer thermus thermophilus hb8
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (250 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PO4 is 50.00% similar to enzyme reactant D-glyceraldehyde
2al8
Rajini's model
Source: Schistosoma mansoni. Blood fluke
Chain: A (250 residues)
2btm
Does the his12-lys13 pair play a role in the adaptation of thermophilic tims to high temperatures?
Source: Geobacillus stearothermophilus. Organism_taxid: 1422. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (251 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2dp3
Crystal structure of a double mutant (c202a/a198v) of triose isomerase from giardia lamblia
Source: Giardia intestinalis. Organism_taxid: 5741. Strain: wb strain. Gene: gltim. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (255 residues) CATH domain: 3.20.20.70
2fi6
A theoretical model of triose phosphate isomerase from plasmodium vivax
Source: Plasmodium vivax
Chain: A (248 residues)
2h6r
Crystal structure of triosephosphate isomerase (tim) from methanocaldococcus jannaschii
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: dsm 2661. Gene: tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H (203 residues) CATH domain: 3.20.20.70
2i9e
Structure of triosephosphate isomerase of tenebrio molitor
Source: Tenebrio molitor. Yellow mealworm. Organism_taxid: 7067. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (246 residues) CATH domain: 3.20.20.70
2iam
Structural basis for recognition of mutant self by a tumor- specific, mhc class ii-restricted tcr
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: hla-drb1. Gene: tpi1, tpi.
Chain: P (15 residues)
2ian
Structural basis for recognition of mutant self by a tumor- specific, mhc class ii-restricted tcr
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: hla-drb1. Gene: tpi1, tpi.
Chains: C, H, M, R (15 residues)
2j24
The functional role of the conserved active site proline of triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (249 residues) CATH domain: 3.20.20.70
2j27
The functional role of the conserved active site proline of triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2j3a
Theortical model of uv pigmented mutant of pseudomonas sp. Ldc-5
Source: Pseudomonas sp. Ldc-5. Pseudomonas. Strain: ldc-5. Variant: field isolate. Other_details: madurai collection of pha accumulating pseudomonas strains.
Chain: A (90 residues)
2j3b
Theortical model of uv mutant of (uv-b)pseudomonas sp.Ldc-5 phac1
Source: Pseudomonas sp. Ldc-5. Pseudomonas. Strain: ldc-5. Variant: field isolate. Other_details: madurai collection of pha accmulating pseudomonas strains
Chain: A (91 residues)
2j3c
Theortical model of mnng mutant of (mnng-s) pseudomonas sp. Ldc-5 phac1
Source: Pseudomonas sp. Ldc-5. Pseudomonas. Strain: ldc-5. Variant: field isolate. Other_details: madurai collection of pha accmulating pseudomonas strains.
Chain: A (89 residues)
2jgq
Kinetics and structural properties of triosephosphate isomerase from helicobacter pylori
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: 26695. Atcc: 700392d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (232 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PO4 is 50.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2jk2
Structural basis of human triosephosphate isomerase deficiency. Crystal structure of the wild type enzyme.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (245 residues) CATH domain: 3.20.20.70
2oma
Crystallographic analysis of a chemically modified triosepho isomerase from trypanosoma cruzi with dithiobenzylamine (dt
Source: Trypanosoma cruzi. Organism_taxid: 5693. Strain: mexican ninoa strain. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (250 residues) CATH domain: 3.20.20.70
2v0t
The a178l mutation in thE C-terminal hinge of the flexible loop-6 of triosephosphate isomerase (tim) induces a more closed conformation of this hinge region in dimeric and monomeric tim
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C, D, E, F, G, H (243 residues) CATH domain: 3.20.20.70
2v2c
The a178l mutation in thE C-terminal hinge of the flexible loop-6 of triosephosphate isomerase (tim) induces a more closed conformation of this hinge region in dimeric and monomeric tim
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2v2d
The a178l mutation in thE C-terminal hinge of the flexible loop-6 of triosephosphate isomerase (tim) induces a more closed conformation of this hinge region in dimeric and monomeric tim
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (241 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PO4 is 50.00% similar to enzyme reactant D-glyceraldehyde
2v2h
The a178l mutation in thE C-terminal hinge of the flexible loop-6 of triosephosphate isomerase (tim) induces a more closed conformation of this hinge region in dimeric and monomeric tim
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C (241 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2v5b
The monomerization of triosephosphate isomerase from trypanosoma cruzi
Source: Trypanosoma cruzi. Organism_taxid: 5693. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (237 residues) CATH domain: 3.20.20.70
2v5l
Structures of the open and closed state of trypanosomal triosephosphate isomerase: as observed in a new crystal form: implications for the reaction mechanism
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (249 residues) CATH domain: 3.20.20.70
2vei
Structure-based enzyme engineering efforts with an inactive monomeric tim variant: the importance of a single point mutation for generating an active site with suitable binding properties
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C (238 residues) CATH domain: 3.20.20.70
2vek
Structure-based enzyme engineering efforts with an inactive monomeric tim variant: the importance of a single point mutation for generating an active site with suitable binding properties
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (237 residues) CATH domain: 3.20.20.70
2vel
Structure-based enzyme engineering efforts with an inactive monomeric tim variant: the importance of a single point mutation for generating an active site with suitable binding properties
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (238 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2vem
Structure-based enzyme engineering efforts with an inactive monomeric tim variant: the importance of a single point mutation for generating an active site with suitable binding properties
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (234 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BBR is 90.00% similar to enzyme reactant D-glyceraldehyde
2ven
Structure-based enzyme engineering efforts with an inactive monomeric tim variant: the importance of a single point mutation for generating an active site with suitable binding properties
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (228 residues) CATH domain: 3.20.20.70
2vfd
Crystal structure of the f96s mutant of plasmodium falciparum triosephosphate isomerase
Source: Plasmodium falciparum. Malarial parasite. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
2vfe
Crystal structure of f96s mutant of plasmodium falciparum triosephosphate isomerase with 3-phosphoglycerate bound at the dimer interface
Source: Plasmodium falciparum. Malarial parasite. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 3PG is 90.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2vff
Crystal structure of the f96h mutant of plasmodium falciparum triosephosphate isomerase
Source: Plasmodium falciparum. Malarial parasite. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
2vfg
Crystal structure of the f96h mutant of plasmodium falciparum triosephosphate isomerase with 3- phosphoglycerate bound at the dimer interface
Source: Plasmodium falciparum. Malarial parasite. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 3PG is 90.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2vfh
Crystal structure of the f96w mutant of plasmodium falciparum triosephosphate isomerase complexed with 3- phosphoglycerate
Source: Plasmodium falciparum. Malarial parasite. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 3PG is 90.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2vfi
Crystal structure of the plasmodium falciparum triosephosphate isomerase in the loop closed state with 3- phosphoglycerate bound at the active site and interface
Source: Plasmodium falciparum. Malarial parasite. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 3PG is 90.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
2vom
Structural basis of human triosephosphate isomerase deficiency. Mutation e104d and correlation to solvent perturbation.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C, D (245 residues) CATH domain: 3.20.20.70
2vxn
E65q-tim complexed with phosphoglycolohydroxamate at 0.82 a resolution
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.67% similar to enzyme reactant D-glyceraldehyde
2wsq
Monotim mutant rmm0-1, dimeric form.
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (242 residues) CATH domain: 3.20.20.70
2wsr
Monotim mutant rmm0-1, monomeric form.
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (242 residues) CATH domain: 3.20.20.70
2x0m
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (233 residues) CATH domain: 3.20.20.70
2x16
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (225 residues) CATH domain: 3.20.20.70
2x1r
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (232 residues) CATH domain: 3.20.20.70
2x1s
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (231 residues) CATH domain: 3.20.20.70
2x1t
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (233 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group RES is 71.43% similar to enzyme reactant D-glyceraldehyde
2x1u
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (232 residues) CATH domain: 3.20.20.70
2x2g
Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (233 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 3PG is 90.91% similar to enzyme reactant D-glyceraldehyde
2y61
Crystal structure of leishmanial e65q-tim complexed with s-g phosphate
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: plyss.
Chain: A (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 1GP is 90.00% similar to enzyme reactant D-glyceraldehyde
2y62
Crystal structure of leishmanial e65q-tim complexed with r-g phosphate
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: plyss.
Chain: A (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group G3P is 90.00% similar to enzyme reactant D-glyceraldehyde
2y63
Crystal structure of leishmanial e65q-tim complexed with bromohydroxyacetone phosphate
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: plyss.
Chain: A (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BBR is 90.00% similar to enzyme reactant D-glyceraldehyde
2y6z
Crystallographic structure of gm23 an example of catalytic migration from tim to thiamin phosphate synthase.
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: the gene for the engineered gm23 were origin obtained from trypanosoma brucei
Chain: A (256 residues) CATH domain: 3.20.20.70
2y70
Crystallographic structure of gm23, mutant g89d, an example of catalytic migration from tim to thiamin phosphate synthase.
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (245 residues) CATH domain: 3.20.20.70
2yc6
Crystal structure of a triple mutant (a198v, c202a and c222n triosephosphate isomerase from giardia lamblia complexed wi 2-phosphoglycolic acid
Source: Giardia intestinalis. Organism_taxid: 5741. Strain: wb. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plys.
Chain: A (255 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
2yc7
Crystal structure of a mutant (c202a) of triosephosphate iso from giardia lamblia complexed with 2-phosphoglycolic acid
Source: Giardia intestinalis. Organism_taxid: 5741. Strain: wb. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plys.
Chain: A (256 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
2yc8
Crystal structure of a double mutant (c202a and c222n) of triosephosphate isomerase from giardia lamblia.
Source: Giardia intestinalis. Organism_taxid: 5741. Strain: wb. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plys.
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T (254 residues) CATH domain: 3.20.20.70
2ypi
Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5- angstroms resolution. Implications for catalysis
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
3gvg
Crystal structure of triosephosphate isomerase from mycobact tuberculosis
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: tpia, tpi, rv1438, mt1482, mtcy493.16c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (256 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group GOL is 60.00% similar to enzyme reactant D-glyceraldehyde
3krs
Structure of triosephosphate isomerase from cryptosporidium 1.55a resolution
Source: Cryptosporidium parvum iowa ii. Organism_taxid: 353152. Strain: iowa ii. Gene: cgd1_3040. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (249 residues) CATH domain: 3.20.20.70
3kxq
Crystal structure of triosephosphate isomerase from bartonel henselae at 1.6a resolution
Source: Bartonella henselae. Rochalimaea henselae. Organism_taxid: 38323. Strain: houston-1. Gene: tpia, bh05680. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (237 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group EDO is 40.00% similar to enzyme reactant D-glyceraldehyde
3m9y
Crystal structure of triosephosphate isomerase from methicil resistant staphylococcus aureus at 1.9 angstrom resolution
Source: Staphylococcus aureus. Organism_taxid: 282458. Strain: mrsa252. Gene: sar0830, tpi, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (252 residues) CATH domain: 3.20.20.70
3pf3
Crystal structure of a mutant (c202a) of triosephosphate iso from giardia lamblia derivatized with mmts
Source: Giardia intestinalis. Organism_taxid: 5741. Strain: wb strain. Gene: gltim. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (256 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group GOL is 60.00% similar to enzyme reactant D-glyceraldehyde
3psv
Structure of e97d mutant of tim from plasmodium falciparum
Source: Plasmodium falciparum. Organism_taxid: 5833. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (243 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group EDO is 40.00% similar to enzyme reactant D-glyceraldehyde
3psw
Structure of e97q mutant of tim from plasmodium falciparum
Source: Plasmodium falciparum. Organism_taxid: 5833. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group EDO is 40.00% similar to enzyme reactant D-glyceraldehyde
3pvf
Structure of c126s mutant of plasmodium falciparum triosepho isomerase complexed with pga
Source: Plasmodium falciparum. Organism_taxid: 5833. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
3pwa
Structure of c126a mutant of plasmodium falciparum triosepho isomerase
Source: Plasmodium falciparum. Organism_taxid: 5833. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group EDO is 40.00% similar to enzyme reactant D-glyceraldehyde
3py2
Structure of c126s mutant of plasmodium falciparum triosepho isomerase
Source: Plasmodium falciparum. Organism_taxid: 5833. Gene: tpi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group EDO is 40.00% similar to enzyme reactant D-glyceraldehyde
3q37
Identification of amino acids that account for long-range in in proteins using two triosephosphate isomerases from patho trypanosomes.
Source: Trypanosoma cruzi, trypanosoma brucei organism_taxid: 5693, 5702. Gene: tim. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (242 residues) CATH domain: 3.20.20.70
3qsr
Crystal structure of trichomonas vaginalis triosephosphate i tvag_497370 gene (ile-45 variant)
Source: Trichomonas vaginalis. Organism_taxid: 5722. Gene: tvag_497370. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (251 residues) CATH domain: 3.20.20.70
3qst
Crystal structure of trichomonas vaginalis triosephosphate i tvag_096350 gene (val-45 variant)
Source: Trichomonas vaginalis. Organism_taxid: 5722. Gene: tvag_096350. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (251 residues) CATH domain: 3.20.20.70
3s6d
Crystal structure of a putative triosephosphate isomerase fr coccidioides immitis
Source: Coccidioides immitis rs. Valley fever fungus. Organism_taxid: 246410. Strain: rs. Gene: cimg_07933. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (270 residues) CATH domain: 3.20.20.70
3ta6
Structure of mycobacterium tuberculosis triosephosphate isom
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: mt1482, mtcy493.16c, rv1438, tpi, tpia. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (255 residues) CATH domain: 3.20.20.70
3tao
Structure of mycobacterium tuberculosis triosephosphate isom bound to phosphoglycolohydroxamate
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: mt1482, mtcy493.16c, rv1438, tpi, tpia. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (256 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.67% similar to enzyme reactant D-glyceraldehyde
3th6
Crystal structure of triosephosphate isomerase from rhipicep (boophilus) microplus.
Source: Rhipicephalus microplus. Cattle tick. Organism_taxid: 6941. Strain: porto alegre. Gene: tim. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (244 residues) CATH domain: 3.20.20.70
3tim
The crystal structure of the "open" and the "closed" conformation of the flexible loop of trypanosomal triosephosphate isomerase
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (249 residues) CATH domain: 3.20.20.70
3uwu
Crystal structure of staphylococcus aureus triosephosphate i complexed with glycerol-3-phosphate
Source: Staphylococcus aureus. Organism_taxid: 282458. Strain: mrsa252. Gene: sar0830, tpi, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (253 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group G3P corresponds to enzyme reactant D-glyceraldehyde
3uwv
Crystal structure of staphylococcus aureus triosephosphate i complexed with 2-phosphoglyceric acid
Source: Staphylococcus aureus. Organism_taxid: 282458. Strain: mrsa252. Gene: sar0830, tpi, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (255 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 2PG is 61.54% similar to enzyme reactant D-glyceraldehyde
3uww
Crystal structure of staphylococcus aureus triosephosphate i complexed with 3-phosphoglyceric acid
Source: Staphylococcus aureus. Organism_taxid: 282458. Strain: mrsa252. Gene: sar0830, tpi, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (254 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 3PG is 90.91% similar to enzyme reactant D-glyceraldehyde
3uwy
Crystal structure of triosephosphate isomerase from methicil resistant staphylococcus aureus at 2.4 angstrom resolution
Source: Staphylococcus aureus. Organism_taxid: 282458. Strain: mrsa252. Gene: sar0830, tpi, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (261 residues) CATH domain: 3.20.20.70
3uwz
Crystal structure of staphylococcus aureus triosephosphate i complexed with glycerol-2-phosphate
Source: Staphylococcus aureus. Organism_taxid: 282458. Strain: mrsa252. Gene: sar0830, tpi, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (254 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group G2H is 66.67% similar to enzyme reactant D-glyceraldehyde
3ypi
Electrophilic catalysis in triosephosphase isomerase: the role of histidine-95
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Cell_line: 293.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
4bi5
Crystal structure of a double mutant (c202a and c222d) of triosephosphate isomerase from giardia lamblia.
Source: Giardia intestinalis. Organism_taxid: 5741. Strain: wb. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plys.
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T (254 residues) CATH domain: 3.20.20.70
4bi6
Crystal structure of a triple mutant (a198v, c202a and c222n) of triosephosphate isomerase from giardia lamblia. Complexed with 2-phosphoglycolic acid
Source: Giardia intestinalis. Organism_taxid: 5741. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plys.
Chain: A (255 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
4bi7
Crystal structure of a mutant (c202a) of triosephosphate isomerase from giardia lamblia. Complexed with 2- phosphoglycolic acid
Source: Giardia intestinalis. Organism_taxid: 5741. Strain: wb. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plys.
Chain: A (256 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
4br1
Protease-induced heterodimer of human triosephosphate isomer
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: codonplus.
Chains: A, B (228 residues) CATH domain: 3.20.20.70
4e41
Structural basis for the recognition of mutant self by a tum specific, mhc class ii-restricted t cell receptor g4
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra, hla-dra1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: hla-drb1. Gene: tpi1, tpi. Expression_system_taxid: 562
Chains: C, H (15 residues)
4ff7
Structure of c126s mutant of saccharomyces cerevisiae triose isomerase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: tpi1, ydr050c, yd9609.05c. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGA is 72.73% similar to enzyme reactant D-glyceraldehyde
4g1k
Crystal structure of triosephosphate isomerase from burkhold thailandensis
Source: Burkholderia thailandensis. Organism_taxid: 271848. Strain: e264. Gene: bth_i1058, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (248 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group EDO is 40.00% similar to enzyme reactant D-glyceraldehyde
4gnj
Crystal structure analysis of leishmania siamensis triosepho isomerase
Source: Leishmania sp. Siamensis. Organism_taxid: 438838. Strain: isolate pcm2. Gene: lstim, tim. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.20.20.70
4hhp
Crystal structure of triosephosphate isomerase from trypanos mutant e105d
Source: Trypanosoma cruzi. Organism_taxid: 5693. Strain: mexican ninoa. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group GOL is 60.00% similar to enzyme reactant D-glyceraldehyde
4iot
High-resolution structure of triosephosphate isomerase from
Source: Escherichia coli. Organism_taxid: 316385. Strain: k12 / dh10b
Chains: A, B (254 residues) CATH domain: 3.20.20.70
4jeq
Different contribution of conserved amino acids to the globa properties of homologous enzymes
Source: Trypanosoma cruzi. Organism_taxid: 5693. Strain: mexican ninoa. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (250 residues) CATH domain: 3.20.20.70
4k6a
Revised crystal structure of apo-form of triosephosphate iso (tpia) from escherichia coli at 1.8 angstrom resolution.
Source: Escherichia coli. Organism_taxid: 1110693. Strain: k-12 substr. Mg1655. Gene: ecmds42_3357, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (255 residues) CATH domain: 3.20.20.70
4mkn
Crystal structure of chloroplastic triosephosphate isomerase chlamydomonas reinhardtii at 1.1 a of resolution
Source: Chlamydomonas reinhardtii. Organism_taxid: 3055. Gene: tim, tpic, chlredraft_26265. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (254 residues) CATH domain: 3.20.20.70
4mva
1.43 angstrom resolution crystal structure of triosephosphat isomerase (tpia) from escherichia coli in complex with acet phosphate.
Source: Escherichia coli. Organism_taxid: 595496. Strain: k-12 substr. Mg1655. Gene: bwg_3588, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (255 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UVW is 63.64% similar to enzyme reactant D-glyceraldehyde
4nvt
Crystal structure of triosephosphate isomerase from brucella melitensis
Source: Brucella melitensis. Organism_taxid: 546272. Strain: atcc 23457. Gene: bmea_a1182, tpia. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (249 residues) CATH domain: 3.20.20.70
4o4v
Crystal structure of trichomonas vaginalis triosephosphate i tvag_497370 (ile-45 variant)
Source: Trichomonas vaginalis. Organism_taxid: 5722. Gene: tvag_497370. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (251 residues) CATH domain: 3.20.20.70
4o4w
Crystal structure of trichomonas vaginalis triosephosphate i ile45-gly mutant (tvag_497370)
Source: Trichomonas vaginalis. Organism_taxid: 5722. Gene: tvag_497370. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (250 residues) CATH domain: 3.20.20.70
4o50
Crystal structure of trichomonas vaginalis triosephosphate i ile45-ala mutant (tvag_497370)
Source: Trichomonas vaginalis. Organism_taxid: 5722. Gene: tvag_497370. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (252 residues) CATH domain: 3.20.20.70
4o52
Crystal structure of trichomonas vaginalis triosephosphate i ile45-val mutant (tvag_497370)
Source: Trichomonas vaginalis. Organism_taxid: 5722. Gene: tvag_497370. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (251 residues) CATH domain: 3.20.20.70
4o53
Crystal structure of trichomonas vaginalis triosephosphate i ile45-leu mutant (tvag_497370)
Source: Trichomonas vaginalis. Organism_taxid: 5722. Gene: tvag_497370. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (251 residues) CATH domain: 3.20.20.70
4o54
Crystal structure of trichomonas vaginalis triosephosphate i ile45-phe mutant (tvag_497370)
Source: Trichomonas vaginalis. Organism_taxid: 5722. Gene: tvag_497370. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (252 residues) CATH domain: 3.20.20.70
4o57
Crystal structure of trichomonas vaginalis triosephosphate i ile45-tyr mutant (tvag_497370)
Source: Trichomonas vaginalis. Organism_taxid: 5722. Gene: tvag_497370. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (246 residues) CATH domain: 3.20.20.70
4ohq
Crystal structure of chloroplast triose phosphate isomerase arabidopsis thaliana
Source: Arabidopsis thaliana. Mouse-ear cress,thale-cress. Organism_taxid: 3702. Gene: tim, at2g21170, f26h11.7. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (250 residues)
4owg
Crystal structure of rabbit muscle triosephosphate isomerase complex
Source: Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Tissue: muscle
Chains: A, B (246 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PEP is 66.67% similar to enzyme reactant D-glyceraldehyde
4p61
Chicken triosephosphate isomerase with loop6 mutations, v167 w168e.
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: tpi1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (243 residues) CATH domain: 3.20.20.70
4poc
Structure of triosephosphate isomerase wild type human enzym
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tpi, tpi1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (246 residues)
Bound ligand:   Het Group PO4 is 50.00% similar to enzyme reactant D-glyceraldehyde
4pod
Structure of triosephosphate isomerase i170v mutant human en
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tpi, tpi1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (245 residues)
Bound ligand:   Het Group PO4 is 50.00% similar to enzyme reactant D-glyceraldehyde
4tim
Crystallographic and molecular modeling studies on trypanosomal triosephosphate isomerase: a critical assessment of the predicted and observed structures of the complex with 2-phosphoglycerate
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 2PG is 61.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
4unk
Crystal structure of human triosephosphate isomerase (mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: codon plus ril.
Chains: A, B (245 residues)
4unl
Crystal structure of a single mutant (n71d) of triosephosphate isomerase from human
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: codon plus ril.
Chains: A, B (246 residues)
5tim
Refined 1.83 angstroms structure of trypanosomal triosephosphate isomerase, crystallized in the presence of 2.4 m-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3- phosphate complex
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (249 residues) CATH domain: 3.20.20.70
6tim
The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes
Source: Trypanosoma brucei brucei. Organism_taxid: 5702. Strain: brucei
Chains: A, B (249 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group G3P corresponds to enzyme reactant D-glyceraldehyde 3-phosphate
7tim
Structure of the triosephosphate isomerase- phosphoglycolohydroxamate complex: an analogue of the intermediate on the reaction pathway
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932
Chains: A, B (247 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PGH is 66.00% similar to enzyme reactant D-glyceraldehyde 3-phosphate
8tim
Triose phosphate isomerase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Cell_line: 293. Organ: breast. Tissue: muscle
Chains: A, B (247 residues) CATH domain: 3.20.20.70