_EC 4.3.3.6 Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing). 0 PDB entries  
EC 4.-.-.- Lyases. [3,731 PDB entries]
EC 4.3.-.- Carbon-nitrogen lyases. [246 PDB entries]
EC 4.3.3.- Amine-lyases. [74 PDB entries]
EC 4.3.3.6 Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing). [-]    

Reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H(2)O + phosphate.
 


D-ribose 5-phosphate
+
D-glyceraldehyde 3-phosphate
+
L-glutamine
=
pyridoxal 5'-phosphate
+
L-glutamate
+ 3 × H(2)O
+
phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: The ammonia is provided by the glutaminase subunit and channeled to the active site of the lyase subunit by a 100 A tunnel. The enzyme can also use ribulose 5-phosphate and dihydroxyacetone phosphate. The enzyme complex is found in aerobic bacteria, archeae, fungi and plants.
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There are no PDB entries in enzyme class E.C.4.3.3.6