_EC 4.3.2.6 Gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase. 0 PDB entries  
EC 4.-.-.- Lyases. [3,638 PDB entries]
EC 4.3.-.- Carbon-nitrogen lyases. [242 PDB entries]
EC 4.3.2.- Lyases acting on amides, amidines, etc. [59 PDB entries]
EC 4.3.2.6 Gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase. [-]    

Reaction: Gamma-L-glutamyl-butirosin B = butirosin b + 5-oxoproline.
 


Gamma-L-glutamyl-butirosin B
=
butirosin B
+
5-oxoproline
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: The enzyme catalyzes the last step in the biosynthesis of the aminoglycoside antibiotic butirosin B. The enzyme acts as a cyclotransferase, cleaving the amide bond via transamidation using the alpha-amine of the terminal gamma-L- glutamate of the side chain, releasing it as the cyclic 5-oxoproline.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.4.3.2.6