_EC 4.3.2.3 Ureidoglycolate lyase. 4 PDB entries  
EC 4.-.-.- Lyases. [3,638 PDB entries]
EC 4.3.-.- Carbon-nitrogen lyases. [242 PDB entries]
EC 4.3.2.- Lyases acting on amides, amidines, etc. [59 PDB entries]
EC 4.3.2.3 Ureidoglycolate lyase. [4 PDB entries]    
1xsq

Pathway: AMP Catabolism
Reaction: (S)-ureidoglycolate = glyoxylate + urea.
 


(S)-ureidoglycolate
=
glyoxylate
+
urea
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Ureidoglycolase. Ureidoglycolatase. Ureidoglycolate hydrolase.
Comments: This microbial enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with Ec 3.5.1.116 which releases ammonia rather than urea.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 4 PDB entries in enzyme class E.C.4.3.2.3

  PDB code Protein
1xsq
Crystal structure of ureidoglycolate hydrolase from e.Coli. Northeast structural genomics consortium target et81.
Source: Escherichia coli. Organism_taxid: 562. Gene: alla. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (154 residues) CATH domain: 2.60.120.480
1xsr
X-ray structure of northeast structural genomics consortium target sfr7
Source: Shigella flexneri. Organism_taxid: 623. Gene: alla. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (158 residues) CATH domain: 2.60.120.480
1yqc
Crystal structure of ureidoglycolate hydrolase (alla) from e coli o157:h7
Source: Escherichia coli. Organism_taxid: 83334. Strain: o157:h7. Gene: alla. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (160 residues) CATH domain: 2.60.120.480
Bound ligand:   Het Group GLV corresponds to enzyme product glyoxylate
2bdr
Crystal structure of the putative ureidoglycolate hydrolase from pseudomonas putida, northeast structural genomics targ
Source: Pseudomonas putida. Organism_taxid: 160488. Strain: kt2440. Gene: alla. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (166 residues) CATH domain: 2.60.120.480