_EC 4.2.3.27 Isoprene synthase. 2 PDB entries  
EC 4.-.-.- Lyases. [3,636 PDB entries]
EC 4.2.-.- Carbon-oxygen lyases. [1,771 PDB entries]
EC 4.2.3.- Acting on phosphates. [169 PDB entries]
EC 4.2.3.27 Isoprene synthase. [2 PDB entries]    
3n0f

Reaction: Dimethylallyl diphosphate = isoprene + diphosphate.
 


Dimethylallyl diphosphate
=
isoprene
+
diphosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Ispc. Isps.
Cofactor(s): Mn(2+) or Mg(2+).
Comments: Located in the chloroplast of isoprene-emitting plants, such as poplar and aspen, and may be activitated by light-dependent changes in chloroplast pH and Mg(2+) concentration.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 2 PDB entries in enzyme class E.C.4.2.3.27

  PDB code Protein
3n0f
Crystal structure of isoprene synthase from grey poplar leav (populus x canescens)
Source: Populus tremula x populus alba. Gray poplar. Organism_taxid: 80863. Tissue: leaves. Gene: isps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (531 residues) CATH domains: 1.50.10.130 1.10.600.10
3n0g
Crystal structure of isoprene synthase from grey poplar leav (populus x canescens) in complex with three mg2+ ions and dimethylallyl-s-thiolodiphosphate
Source: Populus tremula x populus alba. Gray poplar. Organism_taxid: 80863. Tissue: leaves. Gene: isps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (521 residues) CATH domains: 1.50.10.130 1.10.600.10
Bound ligand:   Het Group DST is 53.00% similar to enzyme product diphosphate