_EC 4.2.2.15 Anhydrosialidase. 5 PDB entries  
EC 4.-.-.- Lyases. [3,638 PDB entries]
EC 4.2.-.- Carbon-oxygen lyases. [1,772 PDB entries]
EC 4.2.2.- Acting on polysaccharides. [117 PDB entries]
EC 4.2.2.15 Anhydrosialidase. [5 PDB entries]    
1sli

Pathway: Anhydrosialidase
Reaction: Elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.
Other name(s): Anhydroneuraminidase. Sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing). Sialidase L.
Comments: Also acts on N-glycolylneuraminate glycosides. Cf. Ec 3.2.1.18 and Ec 3.2.1.129. Formerly Ec 3.2.1.138.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 5 PDB entries in enzyme class E.C.4.2.2.15

  PDB code Protein
1sli
Leech intramolecular trans-sialidase complexed with dana
Source: Macrobdella decora. North american leech. Organism_taxid: 6405. Gene: t7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: de3.
Chain: A (679 residues) CATH domains: 2.60.120.200 2.120.10.10 2.40.220.10
1sll
Sialidase l from leech macrobdella decora
Source: Macrobdella decora. North american leech. Organism_taxid: 6405. Gene: t7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: de3.
Chain: A (679 residues) CATH domains: 2.60.120.200 2.120.10.10 2.40.220.10
2sli
Leech intramolecular trans-sialidase complexed with 2,7- anhydro-neu5ac, the reaction product
Source: Macrobdella decora. North american leech. Organism_taxid: 6405. Gene: t7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: de3.
Chain: A (679 residues) CATH domains: 2.60.120.200 2.120.10.10 2.40.220.10
3sli
Leech intramolecular trans-sialidase complexed with 2,7- anhydro-neu5ac prepared by soaking with 3'-sialyllactose
Source: Macrobdella decora. North american leech. Organism_taxid: 6405. Gene: t7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: de3.
Chain: A (679 residues) CATH domains: 2.60.120.200 2.120.10.10 2.40.220.10
4sli
Leech intramolecular trans-sialidase complexed with 2- propenyl-neu5ac, an inactive substrate analogue
Source: Macrobdella decora. North american leech. Organism_taxid: 6405. Gene: t7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: de3.
Chain: A (679 residues) CATH domains: 2.60.120.200 2.120.10.10 2.40.220.10