_EC 4.2.2.13 Exo-(1->4)-alpha-D-glucan lyase. 5 PDB entries  
EC 4.-.-.- Lyases. [3,636 PDB entries]
EC 4.2.-.- Carbon-oxygen lyases. [1,771 PDB entries]
EC 4.2.2.- Acting on polysaccharides. [117 PDB entries]
EC 4.2.2.13 Exo-(1->4)-alpha-D-glucan lyase. [5 PDB entries]    
2x2h

Reaction: Linear alpha-glucan = (n-1) 1,5-anhydro-D-fructose + D-glucose.
 

Linear alpha-glucan
= (n-1) 1,5-anhydro-D-fructose
+
D-glucose
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Alpha-1,4-glucan 1,5-anhydro-D-fructose eliminase. Alpha-1,4-glucan exo-lyase. Alpha-1,4-glucan lyase. Exo-(1,4)-alpha-D-glucan lyase. Exo-alpha-1,4-glucan lyase.
Comments: Catalyzes the sequential degradation of (1->4)-alpha-D-glucans from the non-reducing end with the release of 1,5-anhydro-D-fructose. Thus, for an alpha-glucan containing n (1->4)-linked glucose units, the final products are 1 glucose plus (n-1) 1,5-anhydro-D-fructose. Maltose, maltosaccharides and amylose are all completely degraded. Does not degrade (1->6)-alpha-gucosidic bonds and thus the degradation of a branched glucan, such as amylopectin or glycogen, will result in the formation of 1,5-anhydro-D-fructose plus a limit dextrin. Other enzymes involved in the anhydrofructose pathway are
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 5 PDB entries in enzyme class E.C.4.2.2.13

  PDB code Protein
2x2h
Crystal structure of the gracilariopsis lemaneiformis alpha- 1,4-glucan lyase
Source: Gracilariopsis lemaneiformis. Organism_taxid: 2782. Expressed in: pichia angusta. Expression_system_taxid: 559303. Other_details: replicating vector with hars sequence. Colle taping bay, tsingtao, china
Chains: A, B, C, D (1025 residues) CATH domains: 2.60.40.1760 3.20.20.80 2.60.40.1180 2.60.40.1180
Bound ligand:   Het Group GOL is 50.00% similar to enzyme product D-glucose
2x2i
Crystal structure of the gracilariopsis lemaneiformis alpha- 1,4-glucan lyase with acarbose
Source: Gracilariopsis lemaneiformis. Organism_taxid: 2782. Expressed in: pichia angusta. Expression_system_taxid: 559303. Other_details: replicating vector with hars sequence. Colle taping bay, tsingtao, china
Chains: A, B, C, D (1025 residues) CATH domains: 2.60.40.1760 3.20.20.80 2.60.40.1180 2.60.40.1180
Bound ligand:   Het Group GOL is 50.00% similar to enzyme product D-glucose
2x2j
Crystal structure of the gracilariopsis lemaneiformis alpha- 1,4-glucan lyase with deoxynojirimycin
Source: Gracilariopsis lemaneiformis. Organism_taxid: 2782. Expressed in: pichia angusta. Expression_system_taxid: 559303. Other_details: replicating vector with hars sequence. Colle taping bay, tsingtao, china
Chains: A, B, C, D (1025 residues) CATH domains: 2.60.40.1760 3.20.20.80 2.60.40.1180 2.60.40.1180
Bound ligand:   Het Group NOJ is 76.92% similar to enzyme product D-glucose
4amw
Crystal structure of the gracilariopsis lemaneiformis alpha- 1,4-glucan lyase covalent intermediate complex with 5- fluoro-idosyl-fluoride
Source: Gracilariopsis lemaneiformis. Organism_taxid: 2782. Expressed in: pichia angusta. Expression_system_taxid: 559303.
Chains: A, B, C, D (1025 residues) CATH domains: 2.60.40.1760 3.20.20.80 2.60.40.1180 2.60.40.1180
Bound ligand:   Het Group B9D is 84.62% similar to enzyme product D-glucose
4amx
Crystal structure of the gracilariopsis lemaneiformis alpha-1,4-glucan lyase covalent intermediate complex with 5-fluoro-glucosyl-fluoride
Source: Gracilariopsis lemaneiformis. Organism_taxid: 2782. Expressed in: ogataea polymorpha rb11. Expression_system_taxid: 559303
Chains: A, B, C, D (1025 residues) CATH domains: 2.60.40.1760 3.20.20.80 2.60.40.1180 2.60.40.1180
Bound ligand:   Het Group 5GF is 84.62% similar to enzyme product D-glucose