_EC 2-methylcitrate dehydratase. 1 PDB entries  
EC 4.-.-.- Lyases. [3,638 PDB entries]
EC 4.2.-.- Carbon-oxygen lyases. [1,772 PDB entries]
EC 4.2.1.- Hydro-lyases. [1,376 PDB entries]
EC 2-methylcitrate dehydratase. [1 PDB entries]    

Reaction: (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3- tricarboxylate + H(2)O.

(Z)-but-2-ene-1,2,3- tricarboxylate
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase. 2-methylcitrate hydro-lyase.
Comments: Not identical with Ec Specific for (2S,3S)-methylcitrate, showing no activity with (2R,3S)- methylcitrate. Can also use cis-aconitate as a substrate but more slowly. Both this enzyme and Ec are required to complete the isomerization of (2S,3S)-methylcitrate to (2R,3S)-2-methylisocitrate.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.

  PDB code Protein
Crystal structure of 2-methylcitrate dehydratase
Source: Escherichia coli. Organism_taxid: 562. Strain: b834, de3. Gene: prpd, b0334. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (473 residues) CATH domains: 1.10.4100.10 3.30.1330.120