_EC 4.2.1.51 Prephenate dehydratase. 5 PDB entries  
EC 4.-.-.- Lyases. [3,636 PDB entries]
EC 4.2.-.- Carbon-oxygen lyases. [1,771 PDB entries]
EC 4.2.1.- Hydro-lyases. [1,375 PDB entries]
EC 4.2.1.51 Prephenate dehydratase. [5 PDB entries]    
1ecm

Pathway: Phenylalanine and Tyrosine Biosynthesis
Reaction: Prephenate = phenylpyruvate + H(2)O + CO(2).
 


Prephenate
=
phenylpyruvate
+ H(2)O
+
CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: This enzyme in the enteric bacteria also possesses Ec 5.4.99.5 activity and converts chorismate into prephenate.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 5 PDB entries in enzyme class E.C.4.2.1.51

  PDB code Protein
1ecm
Atomic structure of the buried catalytic pocket of escherich chorismate mutase
Source: Escherichia coli. Organism_taxid: 562. Strain: pjs47. Cell_line: nk6024
Chains: A, B (91 residues) CATH domain: 1.20.59.10
Bound ligand:   Het Group TSA corresponds to enzyme reactant Prephenate
2qmx
The crystal structure of l-phe inhibited prephenate dehydrat chlorobium tepidum tls
Source: Chlorobium tepidum tls. Organism_taxid: 194439. Strain: tls, dsm 12025. Atcc: 49652. Gene: phea, ct1666. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (278 residues) CATH domains: 3.40.190.10 3.40.190.10 3.30.70.260
Bound ligands:   Het Group PHE is 84.62% similar to enzyme product phenylpyruvate
  Het Group ACT is 75.00% similar to enzyme product CO(2)
3kbr
The crystal structure of cyclohexadienyl dehydratase precurs pseudomonas aeruginosa pa01
Source: Pseudomonas aeruginosa. Organism_taxid: 287. Strain: pa01. Gene: pa3475, phec, pseudomonas aeruginosa. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (231 residues) CATH domains: 3.40.190.10 3.40.190.10
Bound ligand:   Het Group FMT corresponds to enzyme product CO(2)
3mwb
The crystal structure of prephenate dehydratase in complex w from arthrobacter aurescens to 2.0a
Source: Arthrobacter aurescens. Organism_taxid: 290340. Strain: tc1. Gene: phea, aaur_0101. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (306 residues) CATH domains: 3.40.190.10 3.40.190.10 3.30.70.260
Bound ligand:   Het Group PHE is 84.62% similar to enzyme product phenylpyruvate
4lub
X-ray structure of prephenate dehydratase from streptococcus
Source: Streptococcus mutans. Organism_taxid: 210007. Strain: ua159. Gene: phea, smu_786. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (188 residues) CATH domains: 3.40.190.10 3.30.70.260