_EC 4.2.1.40 Glucarate dehydratase. 17 PDB entries  
EC 4.-.-.- Lyases. [3,636 PDB entries]
EC 4.2.-.- Carbon-oxygen lyases. [1,771 PDB entries]
EC 4.2.1.- Hydro-lyases. [1,375 PDB entries]
EC 4.2.1.40 Glucarate dehydratase. [17 PDB entries]    
1bqg

Reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.
 


D-glucarate
=
5-dehydro-4-deoxy-D-glucarate
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 17 PDB entries in enzyme class E.C.4.2.1.40

  PDB code Protein
1bqg
The structure of the d-glucarate dehydratase protein from pseudomonas putida
Source: Pseudomonas putida. Organism_taxid: 303. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (399 residues) CATH domains: 3.30.390.10 3.20.20.120
1ec7
E. Coli glucarate dehydratase native enzyme
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (429 residues) CATH domains: 3.30.390.10 3.20.20.120
1ec8
E. Coli glucarate dehydratase bound to product 2,3- dihydroxy-5-oxo-hexanedioate
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (442 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group GLR corresponds to enzyme product 5-dehydro-4-deoxy-D-glucarate
1ec9
E. Coli glucarate dehydratase bound to xylarohydroxamate
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (443 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group XYH is 68.00% similar to enzyme reactant D-glucarate
1ecq
E. Coli glucarate dehydratase bound to 4-deoxyglucarate
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (444 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group DXG corresponds to enzyme product 5-dehydro-4-deoxy-D-glucarate
1jct
Glucarate dehydratase, n341l mutant orthorhombic form
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (443 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group GKR corresponds to enzyme reactant D-glucarate
1jdf
Glucarate dehydratase from e.Coli n341d mutant
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D (442 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group GLR corresponds to enzyme product 5-dehydro-4-deoxy-D-glucarate
3mzn
Crystal structure of probable glucarate dehydratase from chromohalobacter salexigens dsm 3043
Source: Chromohalobacter salexigens. Organism_taxid: 290398. Strain: dsm 3043. Gene: csal_2481. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (446 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group GOL is 46.00% similar to enzyme product 5-dehydro-4-deoxy-D-glucarate
3nfu
Crystal structure of probable glucarate dehydratase from chromohalobacter salexigens dsm 3043 complexed with magnesi
Source: Chromohalobacter salexigens. Organism_taxid: 290398. Strain: dsm 3043. Atcc: baa-138, ncimb 13768. Gene: csal_2481. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (441 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group GOL is 46.00% similar to enzyme product 5-dehydro-4-deoxy-D-glucarate
3nxl
Crystal structure of glucarate dehydratase from burkholderia complexed with magnesium
Source: Burkholderia sp. 383. Burkholderia cepacia (strain atcc 17760 / / r18194). Organism_taxid: 269483. Gene: bcep18194_a3396. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (424 residues) CATH domains: 3.30.390.10 3.20.20.120
3pwg
Crystal structure of the mutant s29g.P34a of d-glucarate deh from escherichia coli complexed with product 5-keto-4-deoxy glucarate
Source: Escherichia coli. Organism_taxid: 444449. Strain: o157:h7 str. Ec4042. Gene: ech74042_a2717. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (442 residues) CATH domains: 3.30.390.10 3.20.20.120
3pwi
Crystal structure of the mutant p34a of d-glucarate dehydrat escherichia coli complexed with product 5-keto-4-deoxy-d-gl
Source: Escherichia coli. Organism_taxid: 444449. Strain: o157:h7 str. Ec4042. Gene: ech74042_a2717. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (440 residues) CATH domains: 3.30.390.10 3.20.20.120
3vdg
Crystal structure of enolase msmeg_6132 (target efi-502282) mycobacterium smegmatis str. Mc2 155 complexed with formate acetate
Source: Mycobacterium smegmatis str. Mc2 155. Organism_taxid: 246196. Strain: atcc 700084 / mc(2)155. Gene: msmeg_6132. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (424 residues) CATH domains: 3.30.390.10 3.20.20.120
3vfc
Crystal structure of enolase msmeg_6132 (target efi-502282) mycobacterium smegmatis str. Mc2 155 complexed with tartrat
Source: Mycobacterium smegmatis str. Mc2 155. Organism_taxid: 246196. Strain: atcc 700084 / mc(2)155. Gene: msmeg_6132. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (417 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group TLA is 60.00% similar to enzyme reactant D-glucarate
4g8t
Crystal structure of a glucarate dehydratase related protein actinobacillus succinogenes, target efi-502312, with sodium sulfate bound, ordered loop
Source: Actinobacillus succinogenes. Organism_taxid: 339671. Strain: 130z. Gene: asuc_1847. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (441 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group GOL is 46.15% similar to enzyme product 5-dehydro-4-deoxy-D-glucarate
4gyp
Crystal structure of the heterotetrameric complex of glucd a from e. Coli k-12 mg1655 (efi target efi-506058)
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: b2787, gudd, jw2758, ygcx. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: b2788, gudx, jw2759, ygcy.
Chains: A, B (444 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group CIT is 52.94% similar to enzyme product 5-dehydro-4-deoxy-D-glucarate
4hn8
Crystal structure of a putative d-glucarate dehydratase from pseudomonas mendocina ymp
Source: Pseudomonas mendocina. Organism_taxid: 399739. Strain: ymp. Gene: pmen_1214. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (427 residues) CATH domains: 3.30.390.10 3.20.20.120
Bound ligand:   Het Group GOL is 46.15% similar to enzyme product 5-dehydro-4-deoxy-D-glucarate