_EC 4.2.1.18 Methylglutaconyl-CoA hydratase. 3 PDB entries  
EC 4.-.-.- Lyases. [3,636 PDB entries]
EC 4.2.-.- Carbon-oxygen lyases. [1,771 PDB entries]
EC 4.2.1.- Hydro-lyases. [1,375 PDB entries]
EC 4.2.1.18 Methylglutaconyl-CoA hydratase. [3 PDB entries]    
1hzd

Pathway: Mevalonate Biosynthesis
Reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O.
 


(S)-3-hydroxy-3-methylglutaryl-CoA
=
trans-3-methylglutaconyl-CoA
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 3 PDB entries in enzyme class E.C.4.2.1.18

  PDB code Protein
1hzd
Crystal structure of human auh protein, an RNA-binding homologue of enoyl-coa hydratase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: auh. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (266 residues) CATH domains: 3.90.226.10 1.10.12.10
2zqq
Crystal structure of human auh (3-methylglutaconyl-coa hydratase) mixed with (auuu)24a RNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: auh. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, C, D, E, F (266 residues) CATH domains: 3.90.226.10 1.10.12.10
2zqr
Crystal structure of auh without RNA
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: auh. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, C, D, E, F (266 residues) CATH domains: 3.90.226.10 1.10.12.10