_EC 4.2.1.126 N-acetylmuramic acid 6-phosphate etherase. 3 PDB entries  
EC 4.-.-.- Lyases. [3,613 PDB entries]
EC 4.2.-.- Carbon-oxygen lyases. [1,756 PDB entries]
EC 4.2.1.- Hydro-lyases. [1,361 PDB entries]
EC 4.2.1.126 N-acetylmuramic acid 6-phosphate etherase. [3 PDB entries]    
1nri

Reaction: (R)-lactate + N-acetyl-D-glucosamine 6-phosphate = N-acetylmuramate 6-phosphate + H(2)O.
 


(R)-lactate
+
N-acetyl-D-glucosamine 6-phosphate
= N-acetylmuramate 6-phosphate
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): MurNAc-6-P etherase.
Comments: This enzyme, along with Ec 2.7.1.170, is required for the utilization of anhydro-N-acetylmuramic acid in proteobacteria. The substrate is either imported from the medium or derived from the bacterium's own cell wall murein during cell wall recycling. Formerly Ec 4.2.1.n1.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 3 PDB entries in enzyme class E.C.4.2.1.126

  PDB code Protein
1nri
Crystal structure of putative phosphosugar isomerase hi0754 haemophilus influenzae
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: hi0754. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (248 residues) CATH domain: 3.40.50.10490
4lzj
Crystal structure of murq from h.Influenzae with bound inhib
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: murq. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (293 residues)
Bound ligand:   Het Group 22H is 79.17% similar to enzyme reactant N-acetyl-D-glucosamine
4m0d
Crystal structure of murq from h.Influenzae in apo form
Source: Haemophilus influenzae. Organism_taxid: 71421. Strain: rd kw20. Gene: murq. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (299 residues)