_EC 4.2.1.1 Carbonate dehydratase. 589 PDB entries  
EC 4.-.-.- Lyases. [3,638 PDB entries]
EC 4.2.-.- Carbon-oxygen lyases. [1,772 PDB entries]
EC 4.2.1.- Hydro-lyases. [1,376 PDB entries]
EC 4.2.1.1 Carbonate dehydratase. [589 PDB entries]    
12ca

Reaction: H(2)CO(3) = CO(2) + H(2)O.
 


H(2)CO(3)
=
CO(2)
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Carbonate hydro-lyase. Carbonic anhydrase. Carbonic dehydratase.
Cofactor(s): Zn(2+).
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 589 PDB entries in enzyme class E.C.4.2.1.1

  PDB code Protein
12ca
Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase ii mutants at residue val-121
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1a42
Human carbonic anhydrase ii complexed with brinzolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: human caii. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (256 residues) CATH domain: 3.10.200.10
1am6
Carbonic anhydrase ii inhibitor: acetohydroxamate
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (258 residues) CATH domain: 3.10.200.10
1avn
Human carbonic anhydrase ii complexed with the histamine activator
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Cell: erythrocytes. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
1azm
Drug-protein interactions: structure of sulfonamide drug complexed with human carbonic anhydrase i
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1bcd
X-ray crystallographic structure of a complex between human carbonic anhydrase ii and a new topical inhibitor, trifluoromethane sulphonamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1bic
Crystallographic analysis of thr-200-> his human carbonic anhydrase ii and its complex with the substrate, hco3-
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
1bn1
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (257 residues) CATH domain: 3.10.200.10
1bn3
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (257 residues) CATH domain: 3.10.200.10
1bn4
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (257 residues) CATH domain: 3.10.200.10
1bnm
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (257 residues) CATH domain: 3.10.200.10
1bnn
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (257 residues) CATH domain: 3.10.200.10
1bnq
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (256 residues) CATH domain: 3.10.200.10
1bnt
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (256 residues) CATH domain: 3.10.200.10
1bnu
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (256 residues) CATH domain: 3.10.200.10
1bnv
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (257 residues) CATH domain: 3.10.200.10
1bnw
Carbonic anhydrase ii inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (256 residues) CATH domain: 3.10.200.10
1bv3
Human carbonic anhydrase ii complexed with urea
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group URE is 40.00% similar to enzyme product CO(2)
1bzm
Drug-protein interactions: structure of sulfonamide drug complexed with human carbonic anhydrase i
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (260 residues) CATH domain: 3.10.200.10
1ca2
Refined structure of human carbonic anhydrase ii at 2.0 angstroms resolution
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1ca3
Unexpected ph-dependent conformation of his-64, the proton shuttle of carbonic anhydrase ii.
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cah
Structure of cobalt carbonic anhydrase complexed with bicarbonate
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
1cai
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1caj
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1cak
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1cal
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1cam
Structural analysis of the zinc hydroxide-thr 199-glu 106 hydrogen bonding network in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
1can
Crystallographic studies of the binding of protonated and unprotonated inhibitors to carbonic anhydrase using hydrogen sulphide and nitrate anions
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (260 residues) CATH domain: 3.10.200.10
1cao
Crystallographic studies of the binding of protonated and unprotonated inhibitors to carbonic anhydrase using hydrogen sulphide and nitrate anions
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (260 residues) CATH domain: 3.10.200.10
1cay
Wild-type and e106q mutant carbonic anhydrase complexed with acetate
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACY is 75.00% similar to enzyme product CO(2)
1caz
Wild-type and e106q mutant carbonic anhydrase complexed with acetate
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACY is 75.00% similar to enzyme product CO(2)
1ccs
Structure-assisted redesign of a protein-zinc binding site with femtomolar affinity
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cct
Structure-assisted redesign of a protein-zinc binding site with femtomolar affinity
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1ccu
Structure-assisted redesign of a protein-zinc binding site with femtomolar affinity
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cil
The positions of his-64 and a bound water in human carbonic anhydrase ii upon binding three structurally related inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1cim
The positions of his-64 and a bound water in human carbonic anhydrase ii upon binding three structurally related inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1cin
The positions of his-64 and a bound water in human carbonic anhydrase ii upon binding three structurally related inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1cnb
Compensatory plastic effects in the redesign of protein- zinc binding sites
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BME is 40.00% similar to enzyme product CO(2)
1cnc
Compensatory plastic effects in the redesign of protein- zinc binding sites
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cng
X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding site
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2.
Chain: A (257 residues) CATH domain: 3.10.200.10
1cnh
X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding site
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2.
Chain: A (257 residues) CATH domain: 3.10.200.10
1cni
X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding site
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2.
Chain: A (257 residues) CATH domain: 3.10.200.10
1cnj
X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding site
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2.
Chain: A (257 residues) CATH domain: 3.10.200.10
1cnk
X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding site
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2.
Chain: A (257 residues) CATH domain: 3.10.200.10
1cnw
Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase ii influence binding constants
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1cnx
Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase ii influence binding constants
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1cny
Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase ii influence binding constants
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1cra
The complex between human carbonic anhydrase ii and the aromatic inhibitor 1,2,4-triazole
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (260 residues) CATH domain: 3.10.200.10
1crm
Structure and function of carbonic anhydrases
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1cva
Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cvb
Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cvc
Redesigning the zinc binding site of human carbonic anhydrase ii: structure of a his2asp-zn2+ metal coordination polyhedron
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cvd
Structural consequences of redesigning a protein-zinc binding site
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cve
Structural consequences of redesigning a protein-zinc binding site
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cvf
Structural consequences of redesigning a protein-zinc binding site
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1cvh
Structural consequences of redesigning a protein-zinc binding site
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1czm
Drug-protein interactions: structure of sulfonamide drug complexed with human carbonic anhydrase i
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (260 residues) CATH domain: 3.10.200.10
1dca
Structure of an engineered metal binding site in human carbonic anhydrase ii reveals the architecture of a regulatory cysteine switch
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1dcb
Structure of an engineered metal binding site in human carbonic anhydrase ii reveals the architecture of a regulatory cysteine switch
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1ddz
X-ray structure of a beta-carbonic anhydrase from the red alga, porphyridium purpureum r-1
Source: Porphyridium purpureum. Organism_taxid: 35688. Variant: r-1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (481 residues) CATH domains: 3.40.1050.10 3.40.1050.10
1dmx
Murine mitochondrial carbonic anyhdrase v at 2.45 angstroms resolution
Source: Mus musculus. House mouse. Organism_taxid: 10090. Strain: balb/cj. Cell_line: bl21. Organ: liver. Organelle: mitochondria. Gene: mca5c. Expressed in: escherichia coli.
Chains: A, B (237 residues) CATH domain: 3.10.200.10
1dmy
Complex between murine mitochondrial carbonic anyhdrase v and the transition state analogue acetazolamide
Source: Mus musculus. House mouse. Organism_taxid: 10090. Strain: balb/cj. Cell_line: bl21. Organ: liver. Organelle: mitochondria. Gene: mca5c. Expressed in: escherichia coli.
Chains: A, B (237 residues) CATH domain: 3.10.200.10
1ekj
The x-ray crystallographic structure of beta carbonic anhydrase from the c3 dicot pisum sativum
Source: Pisum sativum. Pea. Organism_taxid: 3888. Organ: leaf. Cellular_location: nuclear encoded
Chains: A, B, C, D, E, F, G, H (210 residues) CATH domain: 3.40.1050.10
Bound ligand:   Het Group ACT is 75.00% similar to enzyme product CO(2)
1eou
Crystal structure of human carbonic anhydrase ii complexed with an anticonvulsant sugar sulfamate
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: erythrocytes. Cellular_location: cytoplasmerythrocytes
Chain: A (258 residues) CATH domain: 3.10.200.10
1f2w
The mechanism of cyanamide hydration catalyzed by carbonic anhydrase ii revealed by cryogenic x-ray diffraction
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
1flj
Crystal structure of s-glutathiolated carbonic anhydrase iii
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: liver
Chain: A (260 residues) CATH domain: 3.10.200.10
1fql
X-ray crystal structure of zinc-bound f95m/w97v carbonic anhydrase (caii) variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (256 residues) CATH domain: 3.10.200.10
1fqm
X-ray crystal structure of zinc-bound f93i/f95m/w97v carbonic anhydrase (caii) variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (256 residues) CATH domain: 3.10.200.10
1fqn
X-ray crystal structure of metal-free f93i/f95m/w97v carbonic anhydrase (caii) variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
1fqr
X-ray crystal structure of cobalt-bound f93i/f95m/w97v carbonic anhydrase (caii) variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1fr4
X-ray crystal structure of copper-bound f93i/f95m/w97v carbonic anhydrase (caii) variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
1fr7
X-ray crystal structure of zinc-bound f93s/f95l/w97m carbonic anhydrase (caii) variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (256 residues) CATH domain: 3.10.200.10
1fsn
X-ray crystal structure of metal-free f93s/f95l/w97m carbonic anhydrase (caii) variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (257 residues) CATH domain: 3.10.200.10
1fsq
X-ray crystal structure of cobalt-bound f93s/f95l/w97m carbonic anhydrase (caii) variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (258 residues) CATH domain: 3.10.200.10
1fsr
X-ray crystal structure of copper-bound f93s/f95l/w97m carbonic anhydrase (caii) variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (258 residues) CATH domain: 3.10.200.10
1g0e
Site-specific mutant (his64 replaced with ala) of human carbonic anhydrase ii complexed with 4-methylimidazole
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: blood. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
1g0f
Site-specific mutant (his64 replaced with ala) of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: blood. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
1g1d
Carbonic anhydrase ii complexed with 4-(aminosulfonyl)-n- [(2-fluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g3z
Carbonic anhydrase ii (f131v)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g45
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(2-fluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g46
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(2,3-difluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g48
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(2,6-difluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g4j
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(2,3,4,5,6-pentafluorophenyl)methyl]- benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g4o
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-phenylmethylbenzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g52
Carbonic anhydrase ii complexed with 4-(aminosulfonyl)-n- [(2,3-difluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g53
Carbonic anhydrase ii complexed with 4-(aminosulfonyl)-n- [(2,6-difluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g54
Carbonic anhydrase ii complexed with 4-(aminosulfonyl)-n- [(2,3,4,5,6-pentafluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1g6v
Complex of the camelid heavy-chain antibody fragment cab- ca05 with bovine carbonic anhydrase
Source: Bos taurus. Cattle. Organism_taxid: 9913. Camelus dromedarius. Arabian camel. Organism_taxid: 9838. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (256 residues) CATH domain: 3.10.200.10
1h4n
H94n carbonic anhydrase ii complexed with tris
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Gene: caii. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: this caii variant was produced using oligonucleotide-directed mutagenesis of the cloned human
Chain: A (257 residues) CATH domain: 3.10.200.10
1h9n
H119n carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Gene: caii. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: this caii variant was produced using oligonucleotide-directed mutagenesis of the cloned human
Chain: A (257 residues) CATH domain: 3.10.200.10
1h9q
H119q carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Gene: caii. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: this caii variant was produced using oligonucleotide-directed mutagenesis of the cloned human
Chain: A (255 residues) CATH domain: 3.10.200.10
1hca
Unexpected ph-dependent conformation of his-64, the proton shuttle of carbonic anhydrase ii.
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1hcb
Enzyme-substrate interactions: structure of human carbonic anhydrase i complexed with bicarbonate
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
1hea
Carbonic anhydrase ii (carbonate dehydratase) (hca ii) (E.C.4.2.1.1) mutant with leu 198 replaced by arg (l198r)
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1heb
Structural consequences of hydrophilic amino-acid substitutions in the hydrophobic pocket of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1hec
Structural consequences of hydrophilic amino-acid substitutions in the hydrophobic pocket of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1hed
Structural consequences of hydrophilic amino-acid substitutions in the hydrophobic pocket of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1hug
Differences in anionic inhibition of human carbonic anhydrase i revealed from the structures of iodide and gold cyanide inhibitor complexes
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1huh
Differences in anionic inhibition of human carbonic anhydrase i revealed from the structures of iodide and gold cyanide inhibitor complexes
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
1hva
Engineering the zinc binding site of human carbonic anhydrase ii: structure of the his-94-> cys apoenzyme in a new crystalline form
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1i6o
Crystal structure of e. Coli beta carbonic anhydrase (ecca)
Source: Escherichia coli. Organism_taxid: 562. Gene: yadf. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (213 residues) CATH domain: 3.40.1050.10
1i6p
Crystal structure of e. Coli beta carbonic anhydrase (ecca)
Source: Escherichia coli. Organism_taxid: 562. Gene: yadf. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (214 residues) CATH domain: 3.40.1050.10
1i8z
Carbonic anhydrase ii complexed with al-6629 2h-thieno[3,2- e]-1,2-thiazine-6-sulfonamide, 2-(3-methoxyphenyl)-3-(4- morpholinyl)-, 1,1-dioxide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1i90
Carbonic anhydrase ii complexed with al-8520 2h-thieno[3,2- e]-1,2-thiazine-6-sulfonamide, 4-amino-3,4-dihydro-2-(3- methoxypropyl)-, 1,1-dioxide, (r)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1i91
Carbonic anhydrase ii complexed with al-6619 2h-thieno[3,2- e]-1,2-thiazine-6-sulfonamide, 2-(3-hydroxyphenyl)-3-(4- morpholinyl)-, 1,1-dioxide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1i9l
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(4-fluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1i9m
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(2,4-difluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1i9n
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(2,5-difluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1i9o
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(2,3,4-trifluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1i9p
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(2,4,6-trifluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1i9q
Carbonic anhydrase ii (f131v) complexed with 4- (aminosulfonyl)-n-[(3,4,5-trifluorophenyl)methyl]-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1if4
Carbonic anhydrase ii complexed with 4- fluorobenzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1if5
Carbonic anhydrase ii complexed with 2,6- difluorobenzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1if6
Carbonic anhydrase ii complexed with 3,5- difluorobenzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1if7
Carbonic anhydrase ii complexed with (r)-n-(3-indol-1-yl-2- methyl-propyl)-4-sulfamoyl-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1if8
Carbonic anhydrase ii complexed with (s)-n-(3-indol-1-yl-2- methyl-propyl)-4-sulfamoyl-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1if9
Carbonic anhydrase ii complexed with n-[2-(1h-indol-5-yl)- butyl]-4-sulfamoyl-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1j9w
Solution structure of the cai michigan 1 variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product CO(2)
1jcz
Crystal structure of the extracellular domain of human carbo anhydrase xii
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (260 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACY is 75.00% similar to enzyme product CO(2)
1jd0
Crystal structure of the extracellular domain of human carbo anhydrase xii complexed with acetazolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (260 residues) CATH domain: 3.10.200.10
1jv0
The crystal structure of the zinc(ii) adduct of the cai michigan 1 variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product CO(2)
1keq
Crystal structure of f65a/y131c carbonic anhydrase v, covalently modified with 4-chloromethylimidazole
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: mca5c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (238 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACY is 75.00% similar to enzyme product CO(2)
1kop
Neisseria gonorrhoeae carbonic anhydrase
Source: Neisseria gonorrhoeae. Organism_taxid: 485. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (223 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BME is 40.00% similar to enzyme product CO(2)
1koq
Neisseria gonorrhoeae carbonic anhydrase
Source: Neisseria gonorrhoeae. Organism_taxid: 485. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (222 residues) CATH domain: 3.10.200.10
1kwq
Human carbonic anhydrase ii complexed with inhibitor 2000-07
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1kwr
Human carbonic anhydrase ii complexed with inhibitor 0134-36
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1lg5
Crystal structure analysis of the hca ii mutant t199p in complex with beta-mercaptoethanol
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BME is 40.00% similar to enzyme product CO(2)
1lg6
Crystal structure analysis of hca ii mutant t199p in complex with thiocyanate
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
1lgd
Crystal structure analysis of hca ii mutant t199p in complex with bicarbonate
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
1lug
Full matrix error analysis of carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (259 residues) CATH domain: 3.10.200.10
1lzv
Site-specific mutant (tyr7 replaced with his) of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (256 residues) CATH domain: 3.10.200.10
1moo
Site specific mutant (h64a) of human carbonic anhydrase ii at high resolution
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (256 residues) CATH domain: 3.10.200.10
1mua
Structure and energetics of a non-proline cis-peptidyl linkage in an engineered protein
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1okl
Carbonic anhydrase ii complex with the 1okl inhibitor 5- dimethylamino-naphthalene-1-sulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1okm
Carbonic anhydrase ii complex with the 1okm inhibitor 4- sulfonamide-[1-(4-aminobutane)]benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
1okn
Carbonic anhydrase ii complex with the 1okn inhibitor 4- sulfonamide-[1-(4-n-(5-fluorescein thiourea)butane)]
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1oq5
Carbonic anhydrase ii in complex with nanomolar inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: from human erythrocytes
Chain: A (256 residues) CATH domain: 3.10.200.10
1q4i
Theoretical structure of chick-carbonic anhydrase ii (ca ii)
Source: Gallus gallus. Chicken
Chain: A (259 residues)
1qq0
Cobalt substituted carbonic anhydrase from methanosarcina th
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (208 residues) CATH domain: 2.160.10.10
1qre
A closer look at the active site of gamma-carbonic anhydrase resolution crystallographic studies of the carbonic anhydra methanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (210 residues) CATH domain: 2.160.10.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
1qrf
A closer look at the active site of gamma-carbonic anhydrase resolution crystallographic studies of the carbonic anhydra methanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (206 residues) CATH domain: 2.160.10.10
1qrg
A closer look and the active site of gamma-carbonic anhydras resolution crystallographic studies of the carbonic anhydra methanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (206 residues) CATH domain: 2.160.10.10
1qrl
A closer look at the active site of gamma-carbonic anhydrase resolution crystallographic studies of the carbonic anhydra methanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (214 residues) CATH domain: 2.160.10.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
1qrm
A closer look at the active site of gamma-carbonic anhydrase resolution crystal structures of the carbonic anhydrase fro methanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (209 residues) CATH domain: 2.160.10.10
1ray
The structure of human carbonic anhydrase ii in complex with bromide and azide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1raz
The structure of human carbonic anhydrase ii in complex with bromide and azide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1rj5
Crystal structure of the extracellular domain of murine carb anhydrase xiv
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ca14, car14, catm. Expressed in: chlorocebus aethiops. Expression_system_taxid: 9534. Expression_system_cell_line: cos-7.
Chains: A, B (259 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACY is 75.00% similar to enzyme product CO(2)
1rj6
Crystal structure of the extracellular domain of murine carb anhydrase xiv in complex with acetazolamide
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ca14, car14, catm. Expressed in: chlorocebus aethiops. Expression_system_taxid: 9534. Expression_system_cell_line: cos-7.
Chains: A, B (259 residues) CATH domain: 3.10.200.10
1rza
X-ray analysis of metal substituted human carbonic anhydrase ii derivatives
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1rzb
X-ray analysis of metal substituted human carbonic anhydrase ii derivatives
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1rzc
X-ray analysis of metal substituted human carbonic anhydrase ii derivatives
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1rzd
X-ray analysis of metal substituted human carbonic anhydrase ii derivatives
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1rze
X-ray analysis of metal substituted human carbonic anhydrase ii derivatives
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
1t75
Crystal structure of escherichia coli beta carbonic anhydras
Source: Escherichia coli. Organism_taxid: 562. Gene: yadf, b0126, sf0123, s0125. Expressed in: escherichia coli k12. Expression_system_taxid: 83333.
Chains: A, B, D, E (214 residues) CATH domain: 3.40.1050.10
1t9n
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1tb0
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: X (258 residues) CATH domain: 3.10.200.10
1tbt
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: X (258 residues) CATH domain: 3.10.200.10
1te3
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: X (258 residues) CATH domain: 3.10.200.10
1teq
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: X (258 residues) CATH domain: 3.10.200.10
1teu
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: X (258 residues) CATH domain: 3.10.200.10
1tg3
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1tg9
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1th9
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1thj
Carbonic anhydrase from methanosarcina
Source: Methanosarcina thermophila. Organism_taxid: 2210
Chains: A, B, C (213 residues) CATH domain: 2.160.10.10
1thk
Effect of shuttle location and ph environment on h+ transfer in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1ttm
Human carbonic anhydrase ii complexed with 667-coumate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Other_details: t7 promoter, ampicillin resistant
Chain: A (258 residues) CATH domain: 3.10.200.10
1uga
Human carbonic anhydrase ii[hcaii] (E.C.4.2.1.1) mutant with ala 65 replaced by phe (a65f)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: caii. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1ugb
Human carbonic anhydrase ii[hcaii] (E.C.4.2.1.1) mutant with ala 65 replaced by gly (a65g)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: caii. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1ugc
Human carbonic anhydrase ii [hcaii] (E.C.4.2.1.1) mutant with ala 65 replaced by his (a65h)
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Gene: caii. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1ugd
Human carbonic anhydrase ii[hcaii] (E.C.4.2.1.1) mutant with ala 65 replaced by ser (a65s)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: caii. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1uge
Human carbonic anhydrase ii [hcaii] (E.C.4.2.1.1) mutant with ala 65 replaced by leu (a65l)
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Gene: caii. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1ugf
Human carbonic anhydrase ii [hcaii] (E.C.4.2.1.1) mutant with ala 65 replaced by thr (a65t)
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Gene: caii. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1ugg
Human carbonic anhydrase ii[hcaii] (E.C.4.2.1.1) mutant with ala 65 replaced by ser (a65s)-orthorhombic form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: caii. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1urt
Murine carbonic anhydrase v
Source: Mus musculus. House mouse. Organism_taxid: 10090. Strain: balb/cj. Cell_line: bl21. Organ: liver. Organelle: mitochondria. Gene: mca5c y64h f65a. Expressed in: escherichia coli.
Chain: A (237 residues) CATH domain: 3.10.200.10
1v9e
Crystal structure analysis of bovine carbonic anhydrase ii
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: erythrocytes
Chains: A, B (259 residues) CATH domain: 3.10.200.10
1v9i
Crystal structure analysis of the site specific mutant (q253c) of bovine carbonic anhydrase ii
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: erythrocytes. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: C (261 residues) CATH domain: 3.10.200.10
1xeg
Crystal structure of human carbonic anhydrase ii complexed w acetate ion
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACT is 75.00% similar to enzyme product CO(2)
1xev
Crystal structure of human carbonic anhydrase ii in a new crystal form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D (258 residues) CATH domain: 3.10.200.10
1xpz
Structure of human carbonic anhydrase ii with 4-[4-o- sulfamoylbenzyl)(4-cyanophenyl)amino]-4h-[1,2,4]-triazole
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1xq0
Structure of human carbonic anhydrase ii with 4-[(3-bromo-4- o-sulfamoylbenzyl)(4-cyanophenyl)amino]-4h-[1,2,4]-triazole
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
1y7w
Crystal structure of a halotolerant carbonic anhydrase from salina
Source: Dunaliella salina. Organism_taxid: 3046. Gene: dca ii. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (274 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACY is 75.00% similar to enzyme product CO(2)
1yda
Structural basis of inhibitor affinity to variants of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1ydb
Structural basis of inhibitor affinity to variants of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1ydc
Structural basis of inhibitor affinity to variants of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
1ydd
Structural basis of inhibitor affinity to variants of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
1ylk
Crystal structure of rv1284 from mycobacterium tuberculosis with thiocyanate
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: rv1284. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (163 residues) CATH domain: 3.40.1050.10
1ym3
Crystal structure of carbonic anhydrase rv3588c from mycobac tuberculosis
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: rv3588c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (193 residues) CATH domain: 3.40.1050.10
1yo0
Proton transfer from his200 in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
1yo1
Proton transfer from his200 in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
1yo2
Proton transfer from his200 in human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
1z93
Human carbonic anhydrase iii:structural and kinetic study of catalysis and proton transfer.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.10.200.10
1z97
Human carbonic anhydrase iii: structural and kinetic study of catalysis and proton transfer.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.10.200.10
1z9y
Carbonic anhydrase ii in complex with furosemide as sulfonam inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (256 residues) CATH domain: 3.10.200.10
1ze8
Carbonic anhydrase ii in complex with a membrane-impermeant sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
1zfk
Carbonic anhydrase ii in complex with n-4-sulfonamidphenyl-n methylbenzosulfonylurease as sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (256 residues) CATH domain: 3.10.200.10
1zfq
Carbonic anhydrase ii in complex with ethoxzolamidphenole as sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (256 residues) CATH domain: 3.10.200.10
1zge
Carbonic anhydrase ii in complex with p-sulfonamido-o,o'- dichloroaniline as sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (256 residues) CATH domain: 3.10.200.10
1zgf
Carbonic anhydrase ii in complex with trichloromethiazide as sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (256 residues) CATH domain: 3.10.200.10
1zh9
Carbonic anhydrase ii in complex with n-4-methyl-1- piperazinyl-n'-(p-sulfonamide)phenylthiourea as sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (256 residues) CATH domain: 3.10.200.10
1znc
Human carbonic anhydrase iv
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: human caiv. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Expression_system_cell_line: cho-cells.
Chains: A, B (262 residues) CATH domain: 3.10.200.10
1zsa
Carbonic anhydrase ii mutant e117q, apo form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
1zsb
Carbonic anhydrase ii mutant e117q, transition state analogue acetazolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
1zsc
Carbonic anhydrase ii mutant e117q, holo form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
2a5v
Crystal structure of m. Tuberculosis beta carbonic anhydrase tetrameric form
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: rv3588c. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (210 residues) CATH domain: 3.40.1050.10
2a8c
Haemophilus influenzae beta-carbonic anhydrase
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (221 residues) CATH domain: 3.40.1050.10
2a8d
Haemophilus influenzae beta-carbonic anhydrase complexed with bicarbonate
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (221 residues) CATH domain: 3.40.1050.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
2abe
Carbonic anhydrase activators: x-ray crystal structure of the adduct of human isozyme ii with l-histidine as a platform for the design of stronger activators
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
2aw1
Carbonic anhydrase inhibitors: valdecoxib binds to a differe site region of the human isoform ii as compared to the stru related cyclooxygenase ii "selective" inhibitor celecoxib
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: erythrocytes. Cellular_location: cytoplasm
Chain: A (257 residues) CATH domain: 3.10.200.10
2ax2
Production and x-ray crystallographic analysis of fully deuterated human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
2ca2
Crystallographic studies of inhibitor binding sites in human carbonic anhydrase ii. A pentacoordinated binding of the scn-ion to the zinc at high p H
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
2cab
Structure, refinement and function of carbonic anhydrase isozymes. Refinement of human carbonic anhydrase i
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
2cba
Structure of native and apo carbonic anhydrase ii and some of its anion-ligand complexes
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
2cbb
Structure of native and apo carbonic anhydrase ii and some of its anion-ligand complexes
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
2cbc
Structure of native and apo carbonic anhydrase ii and some of its anion-ligand complexes
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group FMT corresponds to enzyme product CO(2)
2cbd
Structure of native and apo carbonic anhydrase ii and some of its anion-ligand complexes
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
2cbe
Structure of native and apo carbonic anhydrase ii and some of its anion-ligand complexes
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
2esf
Identification of a novel non-catalytic bicarbonate binding eubacterial beta-carbonic anhydrase
Source: Escherichia coli. Organism_taxid: 562. Gene: can, cynt2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (213 residues) CATH domain: 3.40.1050.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
2eu2
Human carbonic anhydrase ii in complex with novel inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (257 residues) CATH domain: 3.10.200.10
2eu3
Human carbonic anhydrase ii in complex with novel inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (256 residues) CATH domain: 3.10.200.10
2ez7
Carbonic anhydrase activators. Activation of isozymes i, ii, iv, va, vii and xiv with l- and d-histidine and crystallographic analysis of their adducts with isoform ii: engineering proton transfer processes within the active site of an enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
2f14
Tne crystal structure of the human carbonic anhydrase ii in with a fluorescent inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: erythrocytes
Chain: A (257 residues) CATH domain: 3.10.200.10
2fmg
Carbonic anhydrase activators. Activation of isoforms i, ii, iv, va, vii and xiv with l- and d- phenylalanine and crystallographic analysis of their adducts with isozyme ii: sterospecific recognition within the active site of an enzyme and its consequences for the drug design, structure with l-phenylalanine
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
2fmz
Carbonic anhydrase activators. Activation of isoforms i, ii, iv, va, vii and xiv with l- and d- phenylalanine, structure with d-phenylalanine.
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
2fnk
Activation of human carbonic anhydrase ii by exogenous proton donors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hca ii, ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
2fnm
Activation of human carbonic anhdyrase ii by exogenous proton donors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hca ii, ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
2fnn
Activation of human carbonic anhydrase ii by exogenous proton donors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hca ii, ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
2foq
Human carbonic anhydrase ii complexed with two-prong inhibit
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
2fos
Human carbonic anhydrase ii complexed with two-prong inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (259 residues) CATH domain: 3.10.200.10
2fou
Human carbonic anhydrase ii complexed with two-prong inhibit
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (260 residues) CATH domain: 3.10.200.10
2fov
Human carbonic anhydrase ii complexed with two-prong inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (259 residues) CATH domain: 3.10.200.10
2foy
Human carbonic anhydrase i complexed with a two-prong inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (256 residues) CATH domain: 3.10.200.10
2fw4
Carbonic anhydrase activators. The first x-ray crystallographic study of an activator of isoform i, structure with l-histidine.
Source: Homo sapiens. Human. Organism_taxid: 9606
Chains: A, B (257 residues) CATH domain: 3.10.200.10
2gd8
Crystal structure analysis of the human carbonic anhydrase ii in complex with a 2-substituted estradiol bis-sulfamate
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: from human erythrocytes
Chain: A (257 residues) CATH domain: 3.10.200.10
2geh
N-hydroxyurea, a versatile zinc binding function in the design of metalloenzyme inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
2h15
Carbonic anhydrase inhibitors: clashing with ala65 as a means of designing isozyme-selective inhibitors that show low affinity for the ubiquitous isozyme ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
2h4n
H94n carbonic anhydrase ii complexed with acetazolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: bl21. Gene: caii. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: this caii variant was produced using oligonucleotide-directed mutagenesis of the cloned human
Chain: A (257 residues) CATH domain: 3.10.200.10
2hd6
Crystal structure of the human carbonic anhydrase ii in comp hypoxia-activatable sulfonamide.
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
2hfw
Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase iii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca3. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (257 residues) CATH domain: 3.10.200.10
2hfx
Structural and kinetic analysis of proton shuttle residues i active site of human carbonic anhydrase iii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca3. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (259 residues) CATH domain: 3.10.200.10
2hfy
Structural and kinetic analysis of proton shuttle residues i active site of human carbonic anhydrase iii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca3. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (259 residues) CATH domain: 3.10.200.10
2hkk
Carbonic anhydrase activators: solution and x-ray crystallog the interaction of andrenaline with various carbonic anhydr isoforms
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
2hl4
Crystal structure analysis of human carbonic anhydrase ii in with a benzenesulfonamide derivative
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: sigma-aldrich co.
Chain: A (257 residues) CATH domain: 3.10.200.10
2hnc
Crystal structure of the human carbonic anhydrase ii in comp the 5-amino-1,3,4-thiadiazole-2-sulfonamide inhibitor.
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
2hoc
Crystal structure of the human carbonic anhydrase ii in comp the 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-th 2-sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: human erythrocytes
Chain: A (258 residues) CATH domain: 3.10.200.10
2ili
Refine atomic structure of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
2it4
X ray structure of the complex between carbonic anhydrase i and the phosphonate antiviral drug foscarnet
Source: Homo sapiens. Human. Organism_taxid: 9606
Chains: A, B (256 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group PPF is 42.00% similar to enzyme product CO(2)
2nmx
Structure of inhibitor binding to carbonic anhydrase i
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (258 residues) CATH domain: 3.10.200.10
2nn1
Structure of inhibitor binding to carbonic anhydrase i
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (258 residues) CATH domain: 3.10.200.10
2nn7
Structure of inhibitor binding to carbonic anhydrase i
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (258 residues) CATH domain: 3.10.200.10
2nng
Structure of inhibitor binding to carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
2nno
Structure of inhibitor binding to carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (259 residues) CATH domain: 3.10.200.10
2nns
Structure of inhibitor binding to carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (259 residues) CATH domain: 3.10.200.10
2nnv
Structure of inhibitor binding to carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (259 residues) CATH domain: 3.10.200.10
2nwo
Structural and kinetic effect of hydrophobic mutations in the active site of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
2nwp
Structural and kinetic effects of hydrophobic mutations in the active site of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
2nwy
Structural and kinetic effects of hydrophobic mutations on the active site of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
2nwz
Structural and kinetic effects of hydrophobic mutations on the active site of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
2nxr
Structural effects of hydrophobic mutations on the active site of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
2nxs
Structural and kinetic effects of hydrophobic mutations in the active site of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
2nxt
Structural and kinetic effects of hydrophobic mutations in the active site of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
2o4z
Crystal structure of the carbonic anhydrase ii complexed with hydroxysulfamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
2osf
Inhibition of carbonic anhydrase ii by thioxolone: a mechanistic and structural study
Source: Homo sapiens. Human
Chain: A (257 residues) CATH domain: 3.10.200.10
2osm
Inhibition of carbonic anhydrase ii by thioxolone: a mechani structural study
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
2pou
The crystal structure of the human carbonic anhydrase ii in complex with 4,5-dichloro-benzene-1,3-disulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: erythrocytes
Chain: A (258 residues) CATH domain: 3.10.200.10
2pov
The crystal structure of the human carbonic anhydrase ii in complex with 4-amino-6-chloro-benzene-1,3-disulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: erythrocytes
Chain: A (257 residues) CATH domain: 3.10.200.10
2pow
The crystal structure of the human carbonic anhydrase ii in complex with 4-amino-6-trifluoromethyl-benzene-1,3- disulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: erythrocytes
Chain: A (257 residues) CATH domain: 3.10.200.10
2q1b
Carbonic anhydrase ii in complex with saccharin
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: from human erythrocytes
Chain: A (256 residues) CATH domain: 3.10.200.10
2q1q
Carbonic anhydrase inhibitors. Interaction of the antiepileptic drug sulthiame with twelve mammalian isoforms: kinetic and x-ray crystallographic studies
Source: Synthetic: yes. Other_details: chemically synthesized. Occurs naturally in humans (homo sapiens).
Chain: A (257 residues) CATH domain: 3.10.200.10
2q38
Carbonic anhydrase ii in complex with saccharin at 1.95 angs
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: from human erythrocytes
Chain: A (256 residues) CATH domain: 3.10.200.10
2qo8
Crystal structure of the complex of hcaii with an indane-sul inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: erythrocytes
Chain: A (259 residues) CATH domain: 3.10.200.10
2qoa
Crystal structure of the complex of hcaii with an indane-sul inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: erythrocytes
Chain: A (257 residues) CATH domain: 3.10.200.10
2qp6
The crystal structure of the complex of hcaii with a bioreductive antitumor derivative
Source: Homo sapiens. Human. Other_details: erythrocytes
Chain: A (258 residues) CATH domain: 3.10.200.10
2vva
Human carbonic anhydrase in complex with co2
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: X (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group CO2 corresponds to enzyme product CO(2)
2vvb
Human carbonic anhydrase ii in complex with bicarbonate
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: X (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BCT is 75.00% similar to enzyme product CO(2)
2wd2
A chimeric microtubule disruptor with efficacy on a taxane resistant cell line
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (254 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group FMT corresponds to enzyme product CO(2)
2wd3
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
2weg
Thermodynamic optimisation of carbonic anhydrase fragment inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
2weh
Thermodynamic optimisation of carbonic anhydrase fragment inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
2wej
Thermodynamic optimisation of carbonic anhydrase fragment inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
2weo
Thermodynamic optimisation of carbonic anhydrase fragment inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
2x7s
Structures of human carbonic anhydrase ii inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (256 residues) CATH domain: 3.10.200.10
2x7t
Structures of human carbonic anhydrase ii inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
2x7u
Structures of human carbonic anhydrase ii inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
2znc
Murine carbonic anhydrase iv
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: murine caiv. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (249 residues) CATH domain: 3.10.200.10
3b1b
The unique structure of wild type carbonic anhydrase alpha-c chlamydomonas reinhardtii
Source: Chlamydomonas reinhardtii. Organism_taxid: 3055
Chains: A, B (310 residues) CATH domain: 3.10.200.10
3b4f
Carbonic anhydrase inhibitors. Interaction of 2- (hydrazinocarbonyl)-3-phenyl-1h-indole-5-sulfonamide with twelve mammalian isoforms: kinetic and x-ray crystallographic studies
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
3bet
Crystal structure of the human carbonic anhydrase ii in comp stx 641 at 1.85 angstroms resolution
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
3bl0
Carbonic anhydrase inhibitors. Interaction of 2-n,n- dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with twelve mammalian isoforms: kinetic and x-ray crystallographic studies
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
3bl1
Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited old leads for new applications
Source: Homo sapiens. Human
Chain: A (256 residues) CATH domain: 3.10.200.10
3c7p
Crystal structure of human carbonic anhydrase ii in complex stx237
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
3ca2
Crystallographic studies of inhibitor binding sites in human carbonic anhydrase ii. A pentacoordinated binding of the scn-ion to the zinc at high p H
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
3caj
Crystal structure of the human carbonic anhydrase ii in comp ethoxzolamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
3cyu
Human carbonic anhydrase ii complexed with cryptophane biose xenon
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3czv
Crystal structure of the human carbonic anhydrase xiii in co acetazolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca13. Expressed in: escherichia coli.
Chains: A, B (258 residues) CATH domain: 3.10.200.10
3d0n
Crystal structure of human carbonic anhydrase xiii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca13. Expressed in: escherichia coli.
Chains: A, B (263 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACT is 75.00% similar to enzyme product CO(2)
3d8w
Use of a carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti- cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
3d92
Human carbonic anhydrase ii bound with substrate carbon diox
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group CO2 corresponds to enzyme product CO(2)
3d93
Apo human carbonic anhydrase ii bound with substrate carbon
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group CO2 corresponds to enzyme product CO(2)
3d9z
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3da2
X-ray structure of human carbonic anhydrase 13 in complex wi inhibitor
Source: Homo sapiens. Organism_taxid: 9606. Gene: ca13. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (262 residues) CATH domain: 3.10.200.10
3daz
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3dbu
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3dc3
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3dc9
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3dcc
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3dcs
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3dcw
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3dd0
Use of carbonic anhydrase ii, ix active-site mimic, for the purpose of screening inhibitors for possible anti-cancer properties
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
3dd8
Carbonic anhydrase inhibitors. Interaction of the antitumor sulfamate emd-486019 with twelve mammalian isoforms: kinetic and x-ray crystallographic studies
Source: Synthetic: yes. Other_details: chemically synthesized. This sequence occurs naturally in humans(homo sapiens).
Chain: A (256 residues) CATH domain: 3.10.200.10
3dv7
Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase ii (n62a)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
3dvb
X-ray crystal structure of mutant n62v human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
3dvc
X-ray crystal structure of mutant n62t of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
3dvd
X-ray crystal structure of mutant n62d of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
3e1v
H. Influenzae beta-carbonic anhydrase, variant d44n
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (182 residues) CATH domain: 3.40.1050.10
3e1w
H. Influenzae beta-carbonic anhydrase, variant d44n in 100 m bicarbonate
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (182 residues) CATH domain: 3.40.1050.10
3e24
H. Influenzae beta-carbonic anhydrase, variant w39f
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (186 residues) CATH domain: 3.40.1050.10
3e28
H. Influenzae beta-carbonic anhydrase, variant y181f
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (215 residues) CATH domain: 3.40.1050.10
3e2a
H. Influenzae beta-carbonic anhydrase, variant y181f with 10 bicarbonate
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (209 residues) CATH domain: 3.40.1050.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
3e2w
H. Influenzae beta-carbonic anhydrase, variant y181f with 1m bicarbonate
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (208 residues) CATH domain: 3.40.1050.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
3e2x
H. Influenzae beta-carbonic anhydrase, variant v47a
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (182 residues) CATH domain: 3.40.1050.10
3e31
H. Influenzae beta-carbonic anhydrase, variant v47a
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (183 residues) CATH domain: 3.40.1050.10
3e3f
H. Influenzae beta-carbonic anhydrase, variant v47a with 100 bicarbonate
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (182 residues) CATH domain: 3.40.1050.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
3e3g
H. Influenzae beta-carbonic anhydrase, variant g41a
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (207 residues) CATH domain: 3.40.1050.10
3e3i
H. Influenzae beta-carbonic anhydrase, variant g41a with 100 bicarbonate
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (208 residues) CATH domain: 3.40.1050.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
3efi
Carbonic anhydrase activators: kinetic and x-ray crystallographic study for the interaction of d- and l- tryptophan with the mammalian isoforms i-xiv
Source: Synthetic: yes. Other_details: chemically synthesized. This sequence occurs naturally in humans(homo sapiens).
Chain: A (256 residues) CATH domain: 3.10.200.10
3eft
Crystal structure of the complex between carbonic anhydrase ii and a spin-labeled sulfonamide incorporating tempo moiety
Source: Synthetic: yes. Other_details: chemically synthesized. This sequence occurs naturally in humans(homo sapiens).
Chain: A (256 residues) CATH domain: 3.10.200.10
3eyx
Crystal structure of carbonic anhydrase nce103 from saccharomyces cerevisiae
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: s288c. Gene: nce103. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (197 residues) CATH domain: 3.40.1050.10
Bound ligand:   Het Group ACT is 75.00% similar to enzyme product CO(2)
3f4x
Carbonic anhydrase inhibitors. Comparison of chlorthalidone and indapamide x-ray crystal structures in adducts with isozyme ii: when three water molecules make the difference
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
3f7b
Crystal structure of soluble domain of ca4 in complex with s molecule.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (257 residues) CATH domain: 3.10.200.10
3f7u
Crystal structure of soluble domain of ca4 in complex with s molecule.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (247 residues) CATH domain: 3.10.200.10
3f8e
Coumarins are a novel class of suicide carbonic anhydrase in
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: the protein was purchased from sigma-aldrich
Chain: A (256 residues) CATH domain: 3.10.200.10
3fe4
Crystal structure of human carbonic anhydrase vi
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca6. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (244 residues) CATH domain: 3.10.200.10
3ffp
X ray structure of the complex between carbonic anhydrase ii and lc inhibitors
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: this sequence occurs naturally in humans.
Chain: X (256 residues) CATH domain: 3.10.200.10
3fw3
Crystal structure of soluble domain of ca4 in complex with d
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (249 residues) CATH domain: 3.10.200.10
3gz0
Apo-human carbonic anhydrase ii revisited: implications of the loss of a metal in protein structure, stability and solvent network
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3hfp
Crystal structure of teh complex between ca ii and the activ
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
3hkn
Human carbonic anhydrase ii in complex with (2,3,4,6-tetra-o beta-d-galactopyranosyl) -(1-4)-1,2,3,6-tetra-o-acetyl-1-th glucopyranosylsulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, carbonic anhydrase ii. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3hkq
Human carbonic anhydrase ii in complex with 1-s-d- galactopyranosylsulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3hkt
Human carbonic anhydrase ii in complex with alpha-d- glucopyranosyl-(1->4)-1-thio-beta-d- glucopyranosylsulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3hku
Human carbonic anhydrase ii in complex with topiramate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3hlj
Crystal structure of human carbonic anhydrase isozyme ii wit methylthiobenzimidazo[1,2-c][1,2,3]thiadiazol-7-sulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3hs4
Human carbonic anhydrase ii complexed with acetazolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3iai
Crystal structure of the catalytic domain of the tumor-assoc human carbonic anhydrase ix
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca9, g250, mn. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Chains: A, B, C, D (257 residues) CATH domain: 3.10.200.10
3ibi
The crystal structure of the human carbonic anhydrase ii in with an aliphatic sulfamate inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: erythrocytes
Chain: A (257 residues) CATH domain: 3.10.200.10
3ibl
The crystal structure of the human carbonic anhydrase ii in with an aliphatic bis-sulfamate inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: erythrocytes
Chain: A (258 residues) CATH domain: 3.10.200.10
3ibn
The crystal structure of the human carbonic anhydrase ii in with an aliphatic bis-sulfamate inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: erythrocytes
Chain: A (258 residues) CATH domain: 3.10.200.10
3ibu
The crystal structure of the human carbonic anhydrase ii in with an aliphatic sulfamate inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: erythrocytes
Chain: A (258 residues) CATH domain: 3.10.200.10
3ieo
The coumarin-binding site in carbonic anhydrase: the antiepi lacosamide as an example
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: the protein was purchased from sigma-aldrich
Chain: A (256 residues) CATH domain: 3.10.200.10
3igp
Structure of inhibitor binding to carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (259 residues) CATH domain: 3.10.200.10
3iqk
Human carbonic anhydrase ii h64a complexed with thioxolone h products
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3k2f
Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma
Source: Synthetic: yes. Other_details: this sequence occurs naturally in humans
Chain: A (256 residues) CATH domain: 3.10.200.10
3k34
Human carbonic anhydrase ii with a sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: the protein was purchased from sigma
Chain: A (258 residues) CATH domain: 3.10.200.10
3k7k
Crystal structure of the complex between carbonic anhydrase ii and anions
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: the protein was purchased from sigma- aldrich.
Chain: A (257 residues) CATH domain: 3.10.200.10
3kig
Mutant carbonic anhydrase ii in complex with an azide and an
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3kkx
Neutron structure of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hca ii. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3kne
Carbonic anhydrase ii h64c mutant in complex with an in situ triazole
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3koi
Crystal structure of cobalt (iii) human carbonic anhydrase i 6.0
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (256 residues) CATH domain: 3.10.200.10
3kok
Crystal structure of cobalt (ii) human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
3kon
Crystal structure of cobalt (ii) human carbonic anhydrase ii 11.0
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (258 residues) CATH domain: 3.10.200.10
3ks1
Crystal structure of human carbonic anhydrase ii in a double monoclinic cell
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.10.200.10
3ks3
High resolution structure of human carbonic anhydrase ii at 0.9 a
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3kwa
Polyamines inhibit carbonic anhydrases
Source: Homo sapiens. Human. Organism_taxid: 9606. Other_details: the protein was purchased from sigma-aldrich
Chain: A (256 residues) CATH domain: 3.10.200.10
3l14
Human carbonic anhydrase ii complexed with althiazide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3lxe
Human carbonic anhydrase i in complex with topiramate
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: red blood cell
Chains: A, B (256 residues) CATH domain: 3.10.200.10
3m04
Carbonic anhydrase ii in complex with novel sulfonamide inhi
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (255 residues) CATH domain: 3.10.200.10
3m14
Carbonic anhydrase ii in complex with novel sulfonamide inhi
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3m1j
The crystal structure of a nami a-carbonic anhydrase ii addu discloses the mode of action of this novel anticancer metal
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Other_details: the protein is purcahsed from sigma- aldrich
Chain: A (257 residues) CATH domain: 3.10.200.10
3m1k
Carbonic anhydrase in complex with fragment
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (256 residues) CATH domain: 3.10.200.10
3m1q
Carbonic anhydrase ii mutant w5c-h64c with opened disulfide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3m1w
Carbonic anhyrdase ii mutant w5ch64c with closed disulfide b complex with sulfate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (255 residues) CATH domain: 3.10.200.10
3m2n
Crystal structure of human carbonic anhydrase isozyme ii wit (6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonam
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
3m2x
Carbonic anhydrase ii in complex with novel sulfonamide inhi
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3m2y
Carbonic anhydrase ii in complex with novel sulfonamide inhi
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3m2z
Fragment tethered to carbonic anhydrase ii h64c mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group CO3 corresponds to enzyme reactant H(2)CO(3)
3m3x
Crystal structure of human carbonic anhydrase isozyme ii wit (6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfona
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
3m40
Crystal structure of human carbonic anhydrase isozyme ii wit chloro-5-nitropyrimidin-4-yl)amino]benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
3m5e
Crystal structure of human carbonic anhydrase isozyme ii wit (6-chloro-5-formyl-2-methylthiopyrimidin-4-yl) amino]methyl}benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
3m5s
Carbonic anhydrase ii mutant h64c in complex with carbonate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group CO3 corresponds to enzyme reactant H(2)CO(3)
3m5t
Fragment tethered to carbonic anhydrase ii h64c mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group CO3 corresponds to enzyme reactant H(2)CO(3)
3m67
Crystal structure of human carbonic anhydrase isozyme ii wit chloro-5-[(6,7-dihydro-1h-[1,4]dioxino[2,3-f]benzimidazol-2 ylsulfanyl)acetyl]benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3m96
Crystal structure of human carbonic anhydrase isozyme ii wit bromo-1h-benzimidazol-2-yl)sulfanyl]acetyl}-2- chlorobenzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3m98
Crystal structure of human carbonic anhydrase isozyme ii wit benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3mdz
Crystal structure of human carbonic anhydrase vii [isoform 1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca7. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (259 residues) CATH domain: 3.10.200.10
3mf3
Cobalt(ii)-substituted haemophilus influenzae b-carbonic anh
Source: Haemophilus influenzae. Organism_taxid: 727. Gene: can, hi1301. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (220 residues) CATH domain: 3.40.1050.10
Bound ligand:   Het Group ACT is 75.00% similar to enzyme product CO(2)
3mhc
Crystal structure of human cabonic anhydrase ii in adduct wi adamantyl analogue of acetazolamide in a novel hydrophobic pocket
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (257 residues) CATH domain: 3.10.200.10
3mhi
Crystal structure of human carbonic anhydrase isozyme ii wit nitro-6-oxo-1,6-dihydro-4-pyrimidinyl)amino]methyl}benzenes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3mhl
Crystal structure of human carbonic anhydrase isozyme ii wit (6-methoxy-5-nitropyrimidin-4-yl)amino]methyl}benzenesulfon
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3mhm
Crystal structure of human carbonic anhydrase isozyme ii wit (6-benzylamino-5-nitropyrimidin-4-yl)amino]methyl}benzenesu
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3mho
Crystal structure of human carbonic anhydrase isozyme ii wit chloro-5-formyl-2-methylthiopyrimidin-4-yl)amino]benzenesul
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (256 residues) CATH domain: 3.10.200.10
3ml2
Human carbonic anhydsase ii in complex with an aryl sulfonam inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3ml5
Crystal structure of the c183s/c217s mutant of human ca vii with acetazolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca7. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (262 residues) CATH domain: 3.10.200.10
3mmf
Crystal structure of human carbonic anhydrase ii in complex 3,5-triazine-substituted benzenesulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3mna
The crystal structure of human carbonic anhydrase ii in comp 1,3,5-triazine-substituted benzenesulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3mnh
Human carbonic anhydrase ii mutant k170a
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3mni
Human carbonic anhydrase ii mutant k170d
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3mnj
Human carbonic anhydrase ii mutant k170e
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3mnk
Human carbonic anhydrase ii mutant k170h
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3mnu
Carbonic anhydrase inhibitors: crystallographic and solution studies for the interaction of a boron containing aromatic with mammalian isoforms i-xv
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
3mwo
Human carbonic anhydrase ii in a doubled monoclinic cell: a determination
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.10.200.10
3myq
Crystal structure of human carbonic anhydrase isozyme ii wit chloro-5-[(1h-imidazo[4,5-c]quinolin-2-ylsulfanyl) acetyl]benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3mzc
Human carbonic ahydrase ii in complex with a benzenesulfonam inhibitor
Source: Homo sapiens. Organism_taxid: 9606. Gene: cah2_human. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3n0n
Crystal structure of human carbonic anhydrase ii in complex benzenesulfonamide inhibitor
Source: Homo sapiens. Organism_taxid: 9606. Gene: hca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3n2p
Crystal structure of human carbonic anhydrase ii in complex benzenesulfonamide inhibitor
Source: Homo sapiens. Organism_taxid: 9606. Gene: hca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3n3j
Crystal structure of human carbonic anhydrase ii in complex benzenesulfonamide inhibitor
Source: Homo sapiens. Organism_taxid: 9606. Gene: hca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3n4b
Crystal structure of human carbonic anhydrase ii in complex benzenesulfonamide inhibitor
Source: Homo sapiens. Organism_taxid: 9606. Gene: hca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3nb5
Human carbonic anhydrase ii in complex with 2-(3-chloro-4- hydroxyphenyl)-n-(4-sulfamoylphenethyl)acetamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: carbonic anhydrase ii. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3ni5
Carbonic anhydrase inhibitor: c1 family
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: the protein was purchased from sigma-aldrich
Chain: A (256 residues) CATH domain: 3.10.200.10
3nj9
Crystal structure of carbonic anhydrase ii in complex with a inhibitor
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: the protein was purchased from sigma-aldrich
Chain: A (257 residues) CATH domain: 3.10.200.10
3oik
Human carbonic anhydrase ii mutant a65s, n67q (ca ix mimic) 2-ethylestradiol 3,17-o,o-bis-sulfamate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3oil
Human carbonic anhydrase ii mutant a65s, n67q (ca ix mimic) 2-ethylestradiol 3-o-sulfamate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues)
3oim
Human carbonic anhydrase ii bound by 2-ethylestradiol 3-o-su
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3oku
Human carbonic anhydrase ii in complex with 2-ethylestrone-3 sulfamate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3okv
Human carbonic anhydrase ii a65s, n67q (ca ix mimic) bound w ethylestrone 3-o-sulfamate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3otm
Crystal structures of wild-type gamma-carbonic anhydrase fro methanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (205 residues) CATH domain: 2.160.10.10
3otz
Crystal structure of gamma-carbonic anhydrase w19a mutant fr metanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (205 residues) CATH domain: 2.160.10.10
3ou9
Crystal structure of gamma-carbonic anhydrase w19f mutant fr methanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (205 residues) CATH domain: 2.160.10.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
3oup
Crystal structure of the gamma-carbonic anhydrase w19n mutan methanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (205 residues) CATH domain: 2.160.10.10
3ow5
Crystal structure of the y200a mutant of gamma carbonic anhy methanosarcina thermophila
Source: Methanosarcina thermophila. Organism_taxid: 2210. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (205 residues) CATH domain: 2.160.10.10
Bound ligand:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
3oy0
Human carbonic anhydrase ii complexed with 1-(4-(4-(2- (isopropylsulfonyl)phenylamino)-1h-pyrrolo[2,3-b]pyridin-6- 3-methoxyphenyl)piperidin-4-ol
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3oyq
Structure of human carbonic anhydrase ii complexed with 5,6- benzo[h]cinnolin-3-ylamine
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3oys
Human carbonic anhydrase ii complexed with 2-{[4-amino-3-(3- hydroxyprop-1-yn-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]met methyl-3-(2-methylphenyl)quinazolin-4(3h)-one
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3p25
Human carbonic anhydrase ii complexed with 2,3,4,5-tetrafluo sulfonamido-4-(methyl-1,2,3-triazole-4-carboxylate)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3p29
Human carbonic anhydrase ii complexed with 2,3,4,5-tetrafluo sulfonamido-4-(1,2,3-triazole-4-cyclohexane)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3p3h
Human carbonic anhydrase ii in complex with p-(5-ferrocenyl- triazol-1-yl)benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3p3j
Human carbonic anhydrase ii in complex with p-(5-ruthenoceny 3-triazol-1-yl)benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3p44
Human carbonic anhydrase ii in complex with p-(4-ruthenoceny 3-triazol-1-yl)benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3p4v
Human carbonic anhydrase ii in complex with (+)-xylariamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3p55
Human carbonic anhydrase ii in complex with p-(4-ferrocenyl- triazol-1-yl)benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3p58
Human carbonic anhydrase in complex with benzyl (methyl) carbamodithoic acid
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3p5a
Human carbonic anhydrase complexed with sodium morpholinocarbodithioate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3p5l
Human carbonic anhydrase complexed with sodium 4-cyano-4- phenylpiperidine-1-carbodithioate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3pjj
Synthetic dimer of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3po6
Crystal structure of human carbonic anhydrase ii with 6,7-di methyl-3,4-dihydroisoquinoline-2(1h)-sulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACT corresponds to enzyme product CO(2)
3pyk
Human carbonic anhydrase ii as host for pianostool complexes sulfonamide anchor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3qy1
1.54a resolution crystal structure of a beta-carbonic anhydr salmonella enterica subsp. Enterica serovar typhimurium str
Source: Salmonella enterica subsp. Enterica se typhimurium. Organism_taxid: 99287. Strain: lt2. Gene: stm0171, yadf. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (215 residues) CATH domain: 3.40.1050.10
3qyk
Human carbonic anhydrase ii complexed with triple ring benze sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hcaii. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3r16
Human caii bound to n-(4-sulfamoylphenyl)-2-(thiophen-2-yl)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3r17
Hcarbonic anhydrase ii bound to n-(2-fluoro.4-sulfamoylpheny (thiophen-2-yl) acetamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: B (257 residues) CATH domain: 3.10.200.10
3rg3
Crystal structure of the w5e mutant of human carbonic anhydr
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (255 residues) CATH domain: 3.10.200.10
3rg4
Crystal structure of the w5f mutant of human carbonic anhydr
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3rge
Crystal structure of the w5h mutant of human carbonic anhydr
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (256 residues) CATH domain: 3.10.200.10
3rj7
Human carbonic anhydrase ii complexed with its inhibitor rhe triscarbonyl-cyclopentadienyl-carboxy-4-aminomethylbenzene- sulfonamide
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
3rld
Crystal structure of the y7i mutant of human carbonic anhydr
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
3ryj
Carbonic anhydrase complexed with 4-sulfamoyl-n-(2,2,2- trifluoroethyl)benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (257 residues) CATH domain: 3.10.200.10
3ryv
Carbonic anhydrase complexed with n-ethyl-4-sulfamoylbenzami
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (257 residues) CATH domain: 3.10.200.10
3ryx
Fluoroalkyl and alkyl chains have similar hydrophobicities i to the hydrophobic wall of carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (258 residues) CATH domain: 3.10.200.10
3ryy
Fluoroalkyl and alkyl chains have similar hydrophobicities i to the hydrophobic wall of carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3ryz
Fluoroalkyl and alkyl chains have similar hydrophobicities i to the hydrophobic wall of carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
3rz0
Fluoroalkyl and alkyl chains have similar hydrophobicities i to the hydrophobic wall of carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (258 residues) CATH domain: 3.10.200.10
3rz1
Fluoroalkyl and alkyl chains have similar hydrophobicities i to the hydrophobic wall of carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (257 residues) CATH domain: 3.10.200.10
3rz5
Fluoroalkyl and alkyl chains have similar hydrophobicities i to the hydrophobic wall of carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
3rz7
Fluoroalkyl and alkyl chains have similar hydrophobicities i to the hydrophobic wall of carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3rz8
Fluoroalkyl and alkyl chains have similar hydrophobicities i to the hydrophobic wall of carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3s71
The origin of the hydrophobic effect in the molecular recogn arylsulfonamides by carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (258 residues) CATH domain: 3.10.200.10
3s72
The origin of the hydrophobic effect in the molecular recogn arylsulfonamides by carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (257 residues) CATH domain: 3.10.200.10
3s73
The origin of the hydrophobic effect in the molecular recogn arylsulfonamides by carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (257 residues) CATH domain: 3.10.200.10
3s74
The origin of the hydrophobic effect in the molecular recogn arylsulfonamides by carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (257 residues) CATH domain: 3.10.200.10
3s75
The origin of the hydrophobic effect in the molecular recogn arylsulfonamides by carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (258 residues) CATH domain: 3.10.200.10
3s76
The origin of the hydrophobic effect in the molecular recogn arylsulfonamides by carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3s77
The origin of the hydrophobic effect in the molecular recogn arylsulfonamides by carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (258 residues) CATH domain: 3.10.200.10
3s78
The origin of the hydrophobic effect in the molecular recogn arylsulfonamides by carbonic anhydrase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: B (258 residues) CATH domain: 3.10.200.10
3s8x
Crystal structure of human carbonic anhydrase isozyme ii wit methyl-6-oxo-1,6-dihydro-2-pyrimidinyl) sulfanyl]acetyl}benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3s9t
Crystal structure of human carbonic anhydrase isozyme ii wit chloro-5-{[(4,6-dimethyl-2-pyrimidinyl) sulfanyl]acetyl}benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
3sap
Crystal structure of human carbonic anhydrase isozyme ii wit butyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
3sax
Crystal structure of human carbonic anhydrase isozyme ii wit chloro-5-{[(5-ethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesu
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
3sbh
Crystal structure of human carbonic anhydrase isozyme ii wit 6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (259 residues) CATH domain: 3.10.200.10
3sbi
Crystal structure of human carbonic anhydrase isozyme ii wit pyrimidinylsulfanyl)acetyl]benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
3t5u
Crystal structure of the human carbonic anhydrase ii in comp n-hydroxy benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
3t5z
Crystal structure of the human carbonic anhydrase ii in comp n-methoxy-benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
3t82
Human carbonic anhydrase ii in complex with acetylated carbo sulfamates
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3t83
Human carbonic anhydrase ii in complex with acetylated carbo sulfamates
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3t84
Human carbonic anhydrase ii in complex with acetylated carbo sulfamates
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3t85
Human carbonic anhydrase ii in complex with acetylated carbo sulfamates
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3tmj
Joint x-ray/neutron structure of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (258 residues) CATH domain: 3.10.200.10
3tvn
Human carbonic anhydrase ii proton transfer mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: X (258 residues) CATH domain: 3.10.200.10
3tvo
Human carbonic anhydrase ii proton transfer double mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: X (258 residues) CATH domain: 3.10.200.10
3u3a
Structure of human carbonic anhydrase ii v143i
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: X (258 residues) CATH domain: 3.10.200.10
3u45
Human carbonic anhydrase ii v143a
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: X (257 residues) CATH domain: 3.10.200.10
3u47
Human carbonic anhydrase ii v143l
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (257 residues) CATH domain: 3.10.200.10
3u7c
Crystal structure of the v143i mutant of human carbonic anhy
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
Bound ligands:   Het Group BCT corresponds to enzyme reactant H(2)CO(3)
  Het Group CO2 corresponds to enzyme product CO(2)
3ucj
Coccomyxa beta-carbonic anhydrase in complex with acetazolam
Source: Coccomyxa sp. Pa. Organism_taxid: 41892. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (222 residues) CATH domain: 3.40.1050.10
3uck
Coccomyxa beta-carbonic anhydrase in complex with phosphate
Source: Coccomyxa sp. Pa. Organism_taxid: 41892. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (222 residues) CATH domain: 3.40.1050.10
3ucm
Coccomyxa beta-carbonic anhydrase in complex with thiocyanat
Source: Coccomyxa sp. Pa. Organism_taxid: 41892. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (222 residues) CATH domain: 3.40.1050.10
3ucn
Coccomyxa beta-carbonic anhydrase in complex with azide
Source: Coccomyxa sp. Pa. Organism_taxid: 41892. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (222 residues) CATH domain: 3.40.1050.10
3uco
Coccomyxa beta-carbonic anhydrase in complex with iodide
Source: Coccomyxa sp. Pa. Organism_taxid: 41892. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (222 residues) CATH domain: 3.40.1050.10
3uyn
Hca 3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca3. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (259 residues) CATH domain: 3.10.200.10
3uyq
Hca 3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca3, hca3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (259 residues) CATH domain: 3.10.200.10
3v2j
Effect of sucrose and glycerol as cryoprotectans, on the inh human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3v2m
Effect of sucrose and glycerol as cryoprotectans, on the inh human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3v3f
Kinetic and structural studies of thermostabilized mutants o
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
3v3g
Kinetic and structural studies of thermostabilized mutants o
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: B (258 residues) CATH domain: 3.10.200.10
3v3h
Kinetic and structural studies of thermostabilized mutants o
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: B (258 residues) CATH domain: 3.10.200.10
3v3i
Kinetic and structural studies of thermostabilized mutants o
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: B (257 residues) CATH domain: 3.10.200.10
3v3j
Kinetic and structural studies of thermostabilized mutants o
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
3v5g
Crystal structure of human carbonic anhydrase ii in complex 4-sulfamido-benzenesulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
3v7x
Complex of human carbonic anhydrase ii with n-[2-(3,4- dimethoxyphenyl)ethyl]-4-sulfamoylbenzamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
3vbd
Complex of human carbonic anhydrase ii with 4-(6-methoxy-3,4 dihydroisoquinolin-1-yl)benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
3w6h
Crystal structure of 19f probe-labeled hcai in complex with acetazolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (256 residues) CATH domain: 3.10.200.10
3w6i
Crystal structure of 19f probe-labeled hcai
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, E (256 residues) CATH domain: 3.10.200.10
3znc
Murine carbonic anhydrase iv complexed with brinzolamide
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: murine caiv. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (250 residues) CATH domain: 3.10.200.10
3zp9
Human carbonic anhydrase ii as a scaffold for an artificial transfer hydrogenase
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss
Chain: A (258 residues) CATH domain: 3.10.200.10
4bcw
Carbonic anhydrase ix mimic in complex with (e)-2-(5-bromo- 2-hydroxyphenyl)ethenesulfonic acid
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
4bf1
Three dimensional structure of human carbonic anhydrase ii i complex with 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl) thiophene-2-sulfonamide
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
4bf6
Three dimensional structure of human carbonic anhydrase ii i complex with 5-(1-(3-cyanophenyl)-1h-1,2,3-triazol-4-yl) thiophene-2-sulfonamide
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
4c3t
The carbonic anhydrase from thermovibrio ammonificans reveal interesting intermolecular disulfide contributing to increa thermal stability of this enzyme
Source: Thermovibrio ammonificans. Organism_taxid: 228745. Other_details: dsmz
Chains: A, B (225 residues)
4ca2
Engineering the hydrophobic pocket of carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
4cac
Refined structure of human carbonic anhydrase ii at 2.0 angstroms resolution
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
4cq0
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (256 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group FMT corresponds to enzyme product CO(2)
4dz7
Hca ii in complex with novel sulfonamide inhibitors set d
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4dz9
Hca ii in complex with novel sulfonamide inhibitors set d
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4e3d
Nucleophile recognition as an alternative inhibition mode fo acid based carbonic anhydrase inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4e3f
Nucleophile recognition as an alternative inhibition mode fo acid based carbonic anhydrase inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4e3g
Nucleophile recognition as an alternative inhibition mode fo acid based carbonic anhydrase inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4e3h
Nucleophile recognition as an alternative inhibition mode fo acid based carbonic anhydrase inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4e49
Nucleophile recognition as an alternative inhibition mode fo acid based carbonic anhydrase inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4e4a
Nucleophile recognition as an alternative inhibition mode fo acid based carbonic anhydrase inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4e5q
Human carbonic anhydrase ii in complex with cyanate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
4fik
Human carbonic anhydrase ii h64a complexed with thioxolone h products
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4fl7
The crystal structure of human carbonic anhydrase ii in comp n-(hydroxy)-benzamide
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (257 residues) CATH domain: 3.10.200.10
4fpt
Carbonic anhydrase ii in complex with ethyl (2z,4r)-2- (sulfamoylimino)-1,3-thiazolidine-4-carboxylate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4frc
Carbonic anhydrase ii in complex with n'-sulfamoylpyrrolidin carboximidamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4fu5
Carbonic anhydrase ii in complex with n-[(2z)-1,3-oxazolidin ylidene]sulfuric diamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4fvn
Carbonic anhydrase ii in complex with n-(tetrahydropyrimidin ylidene)sulfuric diamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4fvo
Carbonic anhydrase ii in complex with n-[(2e)-3,4-dihydroqui 2(1h)-ylidene]sulfuric diamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4g0c
Neutron structure of acetazolamide-bound human carbonic anhy reveal molecular details of drug binding.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4g7a
The crystal structure of an alpha carbonic anhydrase from th extremophilic bacterium sulfurihydrogenibium yellowstonense
Source: Sulfurihydrogenibium sp. Yo3aop1. Sulfurihydrogenibium yellowstonense. Organism_taxid: 436114. Gene: syo3aop1_0578. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (224 residues) CATH domain: 3.10.200.10
4gge
Crystal structure of human carbonic anhydrase ii (hcaii) bou cyanate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group 0NM is 50.00% similar to enzyme product CO(2)
4gl1
Structure of h64a/n62l/n67l human carbonic anhydrase ii trip
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: X (258 residues) CATH domain: 3.10.200.10
4hba
Structural and catalytic characterization of a thermal and a variant of human carbonic anhydrase ii containing an engine disulfide bond
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4hew
Activity enhancers of h64a variant of human carbonic anhydra possess multiple binding sites within and around the enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4hey
Activity enhancers of h64a variant of human carbonic anhydra possess multiple binding sites within and around the enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4hez
Activity enhancers of h64a variant of human carbonic anhydra possess multiple binding sites within and around the enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4hf3
Activity enhancers of h64a variant of human carbonic anhydra possess multiple binding sites within and around the enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4ht0
Crystal structure of human carbonic anhydrase isozyme ii wit inhibitor.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
4ht2
Crystal structure of human carbonic anhydrase isozyme xii wi inhibitor.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca12. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (261 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product CO(2)
4hu1
Crystal structure of human carbonic anhydrase isozyme xiii w inhibitor.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca13. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: B, A (260 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product CO(2)
4idr
Human carbonic anhydrase ii proton transfer double mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: X (258 residues) CATH domain: 3.10.200.10
4ilx
Structure of human carbonic anhydrase ii in complex with an sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4ito
Human ca ii inhibition by novel sulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
4itp
Structure of human carbonic anhydrase ii bound to a benzene sulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008
Chain: A (257 residues) CATH domain: 3.10.200.10
4iwz
Structure of hcaii in complex with an acetazolamide derivati
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4js6
Crystal structure of inhibitor-free hcaii h94d
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4jsa
Benzenesulfonamide complexed with hcaii h94d
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4jss
Human carbonic anhydrase ii h94d bound to a bidentate inhibi
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4jsw
Human carbonic anhydrase ii h94c
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4jsz
Benzenesulfonamide bound to hcaii h94c
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4k0s
Structure of hcaix mimic (hcaii with 5 mutations in active s complex with acetazolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2, hcaii. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
4k0t
Structure of hcaix mimic (hcaii with 5 mutations in active s complex with chlorzolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
4k0z
Structure of hcaix mimic (hcaii with 5 mutations in active s complex with methazolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
4k13
Structure of hcaix mimic (hcaii with 5 mutations in active s complex with dorzolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (257 residues) CATH domain: 3.10.200.10
4k1q
Structure of hcaix mimic (hcaii with 5 mutations in active s
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
4kap
The binding of benzoarylsulfonamide ligands to human carboni anhydrase is insensitive to formal fluorination of the liga
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.10.200.10
4kni
Crystal structure of human carbonic anhydrase isozyme ii wit chloro-4-{[(4,6-dimethylpyrimidin-2-yl) sulfanyl]acetyl}benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4knj
Crystal structure of human carbonic anhydrase isozyme ii wit chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4knm
Crystal structure of human carbonic anhydrase isozyme xiii w chloro-4-{[(4,6-dimethylpyrimidin-2-yl) sulfanyl]acetyl}benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca13. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (259 residues) CATH domain: 3.10.200.10
4knn
Crystal structure of human carbonic anhydrase isozyme xiii w chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca13. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: B, A (258 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group ACY is 75.00% similar to enzyme product CO(2)
4kp5
Crystal structure of catalytic domain of human carbonic anhy isozyme xii with 2-chloro-4-[(pyrimidin-2-ylsulfanyl) acetyl]benzenesulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca12. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (261 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product CO(2)
4kp8
Crystal structure of catalytic domain of human carbonic anhy isozyme xii with 3-[(pyrimidin-2-ylsulfanyl)acetyl]benzenes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca12. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (261 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product CO(2)
4kuv
Crystal structure of human carbonic anhydrase ii in complex 5-(3-(4-chlorophenylsulfonyl)ureido)pyridine-2-sulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (256 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BME is 40.00% similar to enzyme product CO(2)
4kuw
Crystal structure of human carbonic anhydrase ii in complex 5-(3-(4-fluorophenylsulfonyl)ureido)pyridine-2-sulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BME is 40.00% similar to enzyme product CO(2)
4kuy
Crystal structure of human carbonic anhydrase ii in complex 5-(3-(o-tolylsulfonyl)ureido)pyridine-2-sulfonamide inhibit
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BME is 40.00% similar to enzyme product CO(2)
4kv0
Crystal structure of human carbonic anhydrase ii in complex 5-(3-tosylureido)pyridine-2-sulfonamide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (257 residues) CATH domain: 3.10.200.10
Bound ligand:   Het Group BME is 40.00% similar to enzyme product CO(2)
4l5u
The structural implications of the secondary co2 binding poc human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4l5v
The structural implications of the secondary co2 binding poc human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4l5w
Structural implications of the secondary co2 binding pocket carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4lhi
Crystal structure of human carbonic anhydrase isozyme ii wit (phenylsulfonyl)thiophene-2-sulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.10.200.10
4lp6
Crystal structure of human carbonic anhydrase ii in complex quinoline oligoamide foldamer
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (257 residues) CATH domain: 3.10.200.10
4lu3
The crystal structure of the human carbonic anhydrase xiv
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca14, unq690/pro1335. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Chain: A (266 residues) CATH domain: 3.10.200.10
4m2r
Human carbonic anhydrase ii in complex with brinzolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4m2u
Carbonic anhydrase ii in complex with dorzolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4m2v
Genetically engineered carbonic anhydrase ix in complex with brinzolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4m2w
Genetically engineered carbonic anhydrase ix in complex with dorzolamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4mdg
Closo carborane carbonic anhydrase inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
4mdl
Meta carborane carbonic anhydrase inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
4mdm
Nido-carborane carbonic anhydrase inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (258 residues) CATH domain: 3.10.200.10
4mlt
Structure of a monodentate 3-hydroxy-4h-pyran-4-thione ligan hcaii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4mlx
Structure of a bidentate 3-hydroxy-4h-pyran-4-thione ligand hcaii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4mo8
The crystal structure of the human carbonic anhydrase ii in with n-[2-(2-methyl-5-nitro-1h-imidazol-1-yl)ethyl]sulfamid
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.10.200.10
4mty
Structure at 2.1 a reolution of a helical aromatic foldamer- complex.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
4n0x
Room temperature crystal structure of human carbonic anhydra complex with thiophene-2-sulfonamide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: B (258 residues) CATH domain: 3.10.200.10
4n16
Structure of cholate bound to human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ca2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (258 residues) CATH domain: 3.10.200.10
4o1j
Crystal structures of two tetrameric beta-carbonic anhydrase filamentous ascomycete sordaria macrospora.
Source: Sordaria macrospora. Organism_taxid: 5147. Strain: atcc mya-333 / dsm 997 / k(l3346) / k-hell. Gene: cas1, smac_03420. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (197 residues) CATH domain: Unassigned
4o1k
Crystal structures of two tetrameric beta-carbonic anhydrase filamentous ascomycete sordaria macrospora.
Source: Sordaria macrospora. Organism_taxid: 5147. Gene: cas2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (211 residues) CATH domain: Unassigned
5ca2
Conformational mobility of his-64 in the thr-200 (right arrow) ser mutant of human carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
5cac
Refined structure of human carbonic anhydrase ii at 2.0 angstroms resolution
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (256 residues) CATH domain: 3.10.200.10
6ca2
Engineering the hydrophobic pocket of carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
7ca2
Engineering the hydrophobic pocket of carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
8ca2
Engineering the hydrophobic pocket of carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10
9ca2
Engineering the hydrophobic pocket of carbonic anhydrase ii
Source: Homo sapiens. Human. Organism_taxid: 9606
Chain: A (255 residues) CATH domain: 3.10.200.10