_EC 4.1.99.16 Geosmin synthase. 0 PDB entries  
EC 4.-.-.- Lyases. [3,636 PDB entries]
EC 4.1.-.- Carbon-carbon lyases. [1,239 PDB entries]
EC 4.1.99.- Other carbon-carbon lyases. [75 PDB entries]
EC 4.1.99.16 Geosmin synthase. [-]    

Reaction: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H(2)O = (-)-geosmin + acetone.
 


(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol
+ H(2)O
=
(-)-geosmin
+
acetone
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Cofactor(s): Mg(2+).
Comments: Geosmin is the cause of the characteristic smell of moist soil. It is a bifunctional enzyme. The N-terminal part of the enzyme is Ec 4.2.3.22, germacradienol synthase, and forms germacradienol from Fpp. The C-terminal part of the enzyme catalyzes the conversion of germacradienol to geosmin via (1S,4aS,8aS)-8,10-dimethyl- 1,2,3,4,4a,5,6,8a-octahydronaphthalene.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.4.1.99.16