_EC 4.1.1.70 Glutaconyl-CoA decarboxylase. 1 PDB entries  
EC 4.-.-.- Lyases. [3,615 PDB entries]
EC 4.1.-.- Carbon-carbon lyases. [1,243 PDB entries]
EC 4.1.1.- Carboxy-lyases. [739 PDB entries]
EC 4.1.1.70 Glutaconyl-CoA decarboxylase. [1 PDB entries]    
1pix

Reaction: 4-carboxybut-2-enoyl-CoA = but-2-enoyl-CoA + CO(2).
 


4-carboxybut-2-enoyl-CoA
=
but-2-enoyl-CoA
+
CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 4-carboxybut-2-enoyl-CoA carboxy-lyase. Glutaconyl coenzyme A decarboxylase. Pent-2-enoyl-CoA carboxy-lyase.
Cofactor(s): Biotin.
 

Biotin
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments: The enzyme from Acidaminococcus fermentans is a biotinyl-protein, requires sodium, and acts as a sodium pump. Prior to the sodium dependent decarboxylation, the carboxylate is transferred to biotin in a sodium independent manner.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.4.1.1.70

  PDB code Protein
1pix
Crystal structure of the carboxyltransferase subunit of the bacterial ion pump glutaconyl-coenzyme a decarboxylase
Source: Acidaminococcus fermentans. Organism_taxid: 905. Gene: gcda. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (586 residues) CATH domains: 1.20.5.680 3.90.226.10 3.90.226.10
Bound ligand:   Het Group FMT corresponds to enzyme product CO(2)