_EC 4.1.1.3 Oxaloacetate decarboxylase. 8 PDB entries  
EC 4.-.-.- Lyases. [3,613 PDB entries]
EC 4.1.-.- Carbon-carbon lyases. [1,243 PDB entries]
EC 4.1.1.- Carboxy-lyases. [735 PDB entries]
EC 4.1.1.3 Oxaloacetate decarboxylase. [8 PDB entries]    
1j3l

Reaction: Oxaloacetate = pyruvate + CO(2).
 


Oxaloacetate
=
pyruvate
+
CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Oxalate beta-decarboxylase. Oxaloacetate carboxy-lyase.
Cofactor(s): Biotin; Sodium or manganese.
 

Biotin
Sodium
or manganese
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments: The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA. The process is accompanied by the extrusion of two sodium ions from cells. Some animal enzymes require manganese.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 8 PDB entries in enzyme class E.C.4.1.1.3

  PDB code Protein
1j3l
Structure of the RNA-processing inhibitor rraa from thermus thermophilis
Source: Thermus thermophilus. Organism_taxid: 274. Strain: hd8. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (164 residues) CATH domain: 3.50.30.40
1nxj
Structure of rv3853 from mycobacterium tuberculosis
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: meng. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (156 residues) CATH domain: 3.50.30.40
1vi4
Crystal structure of regulator of ribonuclease acivity a protein 1
Source: Vibrio cholerae. Organism_taxid: 666. Gene: rraa1, vc2366. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (162 residues) CATH domain: 3.50.30.40
2c5q
Crystal structure of yeast yer010cp
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (233 residues) CATH domain: Unassigned
2nx9
Crystal structure of the carboxyltransferase domain of the oxaloacetate decarboxylase na+ pump from vibrio cholerae
Source: Vibrio cholerae. Organism_taxid: 666. Strain: o395-n1. Gene: oada-2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (451 residues) CATH domain: 3.20.20.70
3b8i
Crystal structure of oxaloacetate decarboxylase from pseudom aeruginosa (pa4872) in complex with oxalate and mg2+.
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Gene: dnase1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (284 residues) CATH domain: 3.20.20.60
Bound ligand:   Het Group OXL is 71.43% similar to enzyme product pyruvate
3c8o
The crystal structure of rraa from pao1
Source: Pseudomonas aeruginosa. Organism_taxid: 287. Strain: k-12. Gene: rraa. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (160 residues) CATH domain: 3.50.30.40
3noj
The structure of hmg/cha aldolase from the protocatechuate d pathway of pseudomonas putida
Source: Pseudomonas putida. Organism_taxid: 351746. Strain: f1. Gene: pput1361, pput_1361. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (235 residues) CATH domain: 3.50.30.40