_EC 4.1.1.23 Orotidine-5'-phosphate decarboxylase. 208 PDB entries  
EC 4.-.-.- Lyases. [3,636 PDB entries]
EC 4.1.-.- Carbon-carbon lyases. [1,239 PDB entries]
EC 4.1.1.- Carboxy-lyases. [742 PDB entries]
EC 4.1.1.23 Orotidine-5'-phosphate decarboxylase. [208 PDB entries]    
1dbt

Pathway: Pyrimidine Biosynthesis
Reaction: Orotidine 5'-phosphate = Ump + CO(2).
 


Orotidine 5'-phosphate
=
UMP
+
CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Omp decarboxylase. OMPdcase. Orotidine-5'-phosphate carboxy-lyase. Orotidylic decarboxylase. Ump synthase. Uridine 5'-monophosphate synthase.
Comments: The enzyme from higher eukaryotes is identical with Ec 2.4.2.10.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 208 PDB entries in enzyme class E.C.4.1.1.23

  PDB code Protein
1dbt
Crystal structure of orotidine 5'-monophosphate decarboxylase from bacillus subtilis complexed with ump
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (237 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
1dqw
Crystal structure of orotidine 5'-phosphate decarboxylase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (267 residues) CATH domain: 3.20.20.70
1dqx
Crystal structure of orotidine 5'-phosphate decarboxylase complexed to 6-hydroxyuridine 5'-phosphate (bmp)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (267 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
1dv7
Crystal structure of orotidine monophosphate decarboxylase
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (212 residues) CATH domain: 3.20.20.70
1dvj
Crystal structure of orotidine monophosphate decarboxylasE C with 6-azaump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (239 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
1eix
Structure of orotidine 5'-monophosphate decarboxylase from e. Coli, co-crystallised with the inhibitor bmp
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (231 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMQ is 95.00% similar to enzyme product UMP
1jjk
Selenomethionine substitution of orotidine-5'-monophosphate decarboxylase from e. Coli causes a change in crystal contacts and space group
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P (231 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
1kly
Orotidine monophosphate decarboxylase d70g mutant complexed azaump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (212 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
1klz
Crystal structure of orotidine monophosphate decarboxylase m complexed with ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (209 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U corresponds to enzyme product UMP
1km0
Crystal structure of orotidine monophosphate decarboxylase mutant d70n complexed with 6-azaump
Source: Methanothermobacter thermautotrophicus. Organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (237 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine 5'-phosphate
1km1
Orotidine monophosphate decarboxylase mutant s127a crystal structure
Source: Methanothermobacter thermautotrophicus. Organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (212 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine 5'-phosphate
1km2
Crystal structure of orotidine monophosphate mutant q185a wi azaump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (211 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
1km3
Crystal structure of odcase mutant k42a complexed with 6-aza
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (212 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
1km4
Crystal structure of odcase mutant k72a complexed with ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (212 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U corresponds to enzyme product UMP
1km5
Crystal structure of odcase mutant d75n complexed with 6-aza
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (212 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
1km6
Crystal structure of odcase mutant d70ak72a complexed with o
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (209 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group OMP corresponds to enzyme reactant Orotidine
1l2u
Orotidine 5'-monophosphate decarboxylase from e. Coli
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (224 residues) CATH domain: 3.20.20.70
1lol
Crystal structure of orotidine monophosphate decarboxylase complex with xmp
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Strain: delta h. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (204 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group XMP is 87.00% similar to enzyme product UMP
1loq
Crystal structure of orotidine monophosphate decarboxylasE C with product ump
Source: Archaea. Organism_taxid: 2157. Strain: delta h. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (209 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U corresponds to enzyme product UMP
1lor
Crystal structure of orotidine 5'-monophosphate complexed wi
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (209 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
1los
Crystal structure of orotidine monophosphate decarboxylase mutant deltar203a complexed with 6-azaump
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Strain: delta h. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (216 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine 5'-phosphate
1lp6
Crystal structure of orotidine monophosphate decarboxylase complexed with cmp
Source: Archaea. Organism_taxid: 2157. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (204 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group C5P is 90.00% similar to enzyme product UMP
1vqt
Crystal structure of orotidine 5'-phosphate decarboxylase (t from thermotoga maritima at 2.00 a resolution
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: pyrf, tm0332. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (191 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product CO(2)
1x1z
Orotidine 5'-monophosphate decarboxylase (odcase) complexed (produced from 6-cyanoump)
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
2aqw
Structure of putative orotidine-monophosphate-decarboxylase plasmodium yoelii (py01515)
Source: Plasmodium yoelii. Organism_taxid: 5861. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (321 residues) CATH domain: 3.20.20.70
2cz5
Crystal structure of orotidine 5'-phosphate decarboxylase fr pyrococcus horikoshii ot3
Source: Pyrococcus horikoshii. Organism_taxid: 53953. Gene: pyrf, ph0731. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (208 residues) CATH domain: 3.20.20.70
2czd
Crystal structure of orotidine 5'-phosphate decarboxylase fr pyrococcus horikoshii ot3 at 1.6 a resolution
Source: Pyrococcus horikoshii. Organism_taxid: 70601. Strain: ot3. Gene: pyrf, ph0731. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (206 residues) CATH domain: 3.20.20.70
2cze
Crystal structure of orotidine 5'-phosphate decarboxylase fr pyrococcus horikoshii ot3 complexed with ump
Source: Pyrococcus horikoshii. Organism_taxid: 70601. Strain: ot3. Gene: pyrf, ph0731. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (208 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
2czf
Crystal structure of orotidine 5'-phosphate decarboxylase fr pyrococcus horikoshii ot3 complexed with xmp
Source: Pyrococcus horikoshii. Organism_taxid: 70601. Strain: ot3. Gene: pyrf, ph0731. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (208 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group XMP is 87.50% similar to enzyme product UMP
2e6y
Covalent complex of orotidine 5'-monophosphate decarboxylase with 6-iodo-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
2eaw
Human ump synthase (c-terminal domain- orotidine 5'- monophosphate decarboxylase)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (256 residues) CATH domain: 3.20.20.70
2f84
Crystal structure of an orotidine-5'-monophosphate decarboxy homolog from p.Falciparum
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: nc_004314. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (323 residues) CATH domain: 3.20.20.70
2fds
Crystal structure of plasmodium berghei orotidine 5'- monophosphate decarboxylase (ortholog of plasmodium falciparum pf10_0225)
Source: Plasmodium berghei. Organism_taxid: 5821. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (318 residues) CATH domain: 3.20.20.70
2jgy
The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (umps)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Other_details: mammalian gene collection (mgc)
Chains: A, B (249 residues) CATH domain: 3.20.20.70
2p1f
Human ump synthase (c-terminal domain-orotidine 5'-monophosp decarboxylase)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (259 residues) CATH domain: 3.20.20.70
2q8l
Crystal structure of orotidine 5'-phosphate decarboxylase fr plasmodium falciparum
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: pf10_0225. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (314 residues) CATH domain: 3.20.20.70
2q8z
Crystal structure of plasmodium falciparum orotidine 5'-phos decarboxylase complexed with 6-amino-ump
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: pf10_0225. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (330 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group NUP is 95.45% similar to enzyme product UMP
  Het Group 7PE is 40.00% similar to enzyme product CO(2)
2qaf
Crystal structure of plasmodium falciparum orotidine 5'-phos decarboxylase covalently modified by 6-iodo-ump
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: ompdc. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (329 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
2qcc
Crystal structure of the orotidine-5'-monophosphate decarbox domain of human ump synthase, apo form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (248 residues) CATH domain: 3.20.20.70
2qcd
Crystal structure of the orotidine-5'-monophosphate decarbox domain of human ump synthase bound to ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (258 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
2qce
Crystal structure of the orotidine-5'-monophosphate decarbox domain of human ump synthase bound to sulfate, glycerol, an
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.20.20.70
2qcf
Crystal structure of the orotidine-5'-monophosphate decarbox domain (asp312asn mutant) of human ump synthase bound to 5-
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 5FU is 95.45% similar to enzyme product UMP
2qcg
Crystal structure of the orotidine-5'-monophosphate decarbox domain of human ump synthase bound to 5-bromo-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (258 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 5BU is 95.45% similar to enzyme product UMP
2qch
Crystal structure of the orotidine-5'-monophosphate decarbox domain of human ump synthase bound to 5-iodo-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (255 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 5IU is 90.91% similar to enzyme product UMP
2qcl
Crystal structure of the orotidine-5'-monophosphate decarbox domain (asp312asn mutant) of human ump synthase bound to om
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (255 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group OMP corresponds to enzyme reactant Orotidine
2qcm
Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (asp312asn mutant) of human ump synthase bound to 6-hydroxymethyl-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group JW5 is 95.00% similar to enzyme reactant Orotidine 5'-phosphate
2qcn
Covalent complex of the orotidine-5'-monophosphate decarboxy domain of human ump synthase with 6-iodo-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
2v30
Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (umps) in complex with its product ump.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Other_details: mammalian gene collection (mgc)
Chains: A, B (262 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
2wns
Human orotate phosphoribosyltransferase (oprtase) domain of uridine 5'-monophosphate synthase (umps) in complex with its substrate orotidine 5'-monophosphate (omp)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (197 residues) CATH domain: 3.40.50.2020
Bound ligand:   Het Group OMP corresponds to enzyme reactant Orotidine 5'-phosphate
2yyt
Crystal structure of uncharacterized conserved protein from geobacillus kaustophilus
Source: Geobacillus kaustophilus. Organism_taxid: 235909. Strain: hta426. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (215 residues) CATH domain: 3.20.20.70
2yyu
Crystal structure of uncharacterized conserved protein from geobacillus kaustophilus
Source: Geobacillus kaustophilus. Organism_taxid: 235909. Strain: hta426. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (225 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group C5P is 90.91% similar to enzyme product UMP
2za1
Crystal structure of orotidine 5'-monophosphate decarboxylase complexed with orotidine 5'-monophosphate from p.Falciparum
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (318 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group OMP corresponds to enzyme reactant Orotidine 5'-phosphate
2za2
Crystal structure of the apo-form of orotidine-5'- monophosphate decarboxylase from p.Falciparum
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (306 residues) CATH domain: 3.20.20.70
2za3
Crystal structure of orotidine 5'-monophosphate decarboxylase complexed with uridine 5'-monophosphate from p.Falciparum
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (315 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
2zcg
Structure and inhibition of orotidine 5'-phosphate decarboxylase from plasmodium falciparum
Source: Plasmodium falciparum. Malaria parasite p. Falciparum. Organism_taxid: 5833. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (318 residues) CATH domain: 3.20.20.70
2zz1
Snapshot of the reaction from 6-cn-ump to bmp catalyzed by o monophosphate deacarboxylase from m. Thermoautotrophicum
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (215 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group 6CN is 88.00% similar to enzyme reactant Orotidine
  Het Group BMP is 95.45% similar to enzyme product UMP
2zz2
Orotidine monophosphate decarboxylase k72a mutant from m. Thermoautotrophicum complexed with 6-cyano-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 6CN is 91.30% similar to enzyme product UMP
2zz3
Covalent complex of orotidine monophosphate decarboxylase d7 from m. Thermoautotrophicus with 6-cyano-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 6CN corresponds to enzyme product UMP
2zz4
Covalent complex of orotidine monophosphate decarboxylase d7 from m. Thermoautotrophicum with 6-cyano-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 6CN corresponds to enzyme product UMP
2zz5
Orotidine monophosphate deacarboxylase d70a/k72a double muta thermoautotrophicum complexed with 6- cyano-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (213 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 6CN is 91.30% similar to enzyme product UMP
2zz6
Covalent complex of orotidine monophosphate decarboxylase fr thermoautotrophicum with 6-azido-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 6AZ corresponds to enzyme product UMP
2zz7
Orotidine monophosphate decarboxylase k72a mutant complexed (produced from 6-iodo-ump)
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3bar
Crystal structure of plasmodium falciparum orotidine 5'-phos decarboxylase covalently modified by 6-azido-ump
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: ompdc. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (323 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
3bgg
Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with bmp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
3bgj
Crystal structure of human orotidine 5'-monophosphate decarb covalently modified by 6-iodo-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
3bk0
Crystal structure of human orotidine 5'-monophosphate decarb complexed with 5-cn-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group CNU is 91.30% similar to enzyme product UMP
3bpw
Crystal structure of p. Falciparum orotidine 5'-monophosphat decarboxylase complexed with xmp
Source: Plasmodium falciparum. Organism_taxid: 5833. Strain: 3d7. Gene: ompdc. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (330 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group XMP is 87.50% similar to enzyme product UMP
3bvj
Crystal structure of human orotidine 5'-monophosphate decarb complexed with xmp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group XMP is 87.50% similar to enzyme product UMP
3dbp
Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with 6-nh2-ump
Source: Homo sapiens. Man. Organism_taxid: 9606. Gene: umps, ok/sw-cl.21. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group NUP is 95.00% similar to enzyme product UMP
3ewu
D312n mutant of human orotidyl-5'-monophosphate decarboxylas complex with 6-acetyl-ump, covalent adduct
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UEP is 91.30% similar to enzyme product UMP
3eww
D312n mutant of human orotidyl-5'-monophosphate decarboxylas complex with 6-cyano-ump, covalent adduct
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
3ewx
K314a mutant of human orotidyl-5'-monophosphate decarboxylas complex with 6-azido-ump, degraded to bmp
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3ewy
K314a mutant of human orotidyl-5'-monophosphate decarboxylas with omp, decarboxylated to ump
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
3ewz
Human orotidyl-5'-monophosphate decarboxylase in complex with 5-cyano-ump
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (258 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group CNU is 91.00% similar to enzyme product UMP
3ex0
Human orotidyl-5'-monophosphate decarboxylase in complex with 6-acetyl-ump
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
3ex1
Human orotidyl-5'-monophosphate decarboxylase soaked with 6- converted to ump
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group 6CN is 88.00% similar to enzyme reactant Orotidine
  Het Group U5P corresponds to enzyme product UMP
3ex2
Human orotidyl-5'-monophosphate decarboxylase in complex wit ump
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 6CN is 91.30% similar to enzyme product UMP
3ex3
Human orotidyl-5'-monophosphate decarboxylase in complex wit ump, covalent adduct
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
3ex4
Human orotidyl-5'-monophosphate decarboxylase in complex with bmp
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
3ex5
Human orotidyl-5'-monophosphate decarboxylase in complex with 6-mercapto-ump
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (255 residues) CATH domain: 3.20.20.70
3ex6
D312n mutant of human orotidyl-5'-monophosphate decarboxylas complex with 6-azido-ump, covalent adduct
Source: Homo sapiens. Organism_taxid: 9606. Gene: umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
3g18
Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (211 residues) CATH domain: 3.20.20.70
3g1a
Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine 5'-phosphate
3g1d
Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U corresponds to enzyme product UMP
3g1f
Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydroorotidine 5'-monophosphate
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M (220 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 2OM corresponds to enzyme reactant Orotidine 5'-phosphate
3g1h
Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M (221 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group H2U corresponds to enzyme product UMP
3g1s
Crystal structure of the mutant d70g of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoautotrophicum
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (209 residues) CATH domain: 3.20.20.70
3g1v
Crystal structure of the mutant d70g of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5-fluorouridine 5'- monophosphate
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (213 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 5FU is 95.00% similar to enzyme product UMP
3g1x
Crystal structure of the mutant d70g of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (213 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U corresponds to enzyme product UMP
3g1y
Crystal structure of the mutant d70n of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with sulfate
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (204 residues) CATH domain: 3.20.20.70
3g22
Crystal structure of the mutant d70n of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U corresponds to enzyme product UMP
3g24
Crystal structure of the mutant d70n of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 6-azauridine 5'- monophosphate
Source: Methanothermobacter thermautotrophicus str. Delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine 5'-phosphate
3g3d
Crystal structure of human orotidine 5'-monophosphate decarb covalently modified by 5-fluoro-6-azido-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gi|13960142, ok/sw-cl.21, umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (256 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 5FU is 95.45% similar to enzyme product UMP
3g3m
Crystal structure of human orotidine 5'-monophosphate decarboxylase covalently modified by 5-fluoro-6-iodo-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gi|13960142, ok/sw-cl.21, umps. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 5FU is 95.00% similar to enzyme product UMP
3gdk
Crystal structure of the orotidine 5'-monophosphate decarboxylase from saccharomyces cerevisiae
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: ura3, yel021w. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (260 residues) CATH domain: 3.20.20.70
3gdl
Crystal structure of the orotidine 5'-monophosphate decarboxylase from saccharomyces cerevisiae complexed with 6-azauridine 5'-monophosphate
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: ura3, yel021w. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine 5'-phosphate
3gdm
Crystal structure of the k93r mutant of the orotidine 5'- monophosphate decarboxylase from saccharomyces cerevisiae
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: ura3, yel021w. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (261 residues) CATH domain: 3.20.20.70
3gdr
Crystal structure of the d91n mutant of the orotidine 5'- monophosphate decarboxylase from saccharomyces cerevisiae
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: ura3, yel021w. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (260 residues) CATH domain: 3.20.20.70
3gdt
Crystal structure of the d91n mutant of the orotidine 5'- monophosphate decarboxylase from saccharomyces cerevisiae complexed with 6-azauridine 5'-monophosphate
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: ura3, yel021w. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (260 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine 5'-phosphate
3l0k
Human orotidyl-5'-monophosphate decarboxylase in complex with 6-acetyl-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps, ok/sw-cl.21. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 6AU is 92.00% similar to enzyme reactant Orotidine 5'-phosphate
3l0n
Human orotidyl-5'-monophosphate decarboxylase in complex with 6-mercapto-ump
Source: Homo sapiens. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (255 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group S5P is 95.00% similar to enzyme product UMP
3l52
Crystal structure of putative orotidine 5'-phosphate decarbo from streptomyces avermitilis ma-4680
Source: Streptomyces avermitilis. Organism_taxid: 227882. Strain: ma-4680. Gene: pyrf, sav6869, sav_6869. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (284 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group ACT is 75.00% similar to enzyme product CO(2)
3ldv
1.77 angstrom resolution crystal structure of orotidine 5'- phosphate decarboxylase from vibrio cholerae o1 biovar eltor str. N16961
Source: Vibrio cholerae o1 biovar el tor. Organism_taxid: 243277. Strain: n16961. Gene: pyrf, vc_1911. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (231 residues) CATH domain: 3.20.20.70
3lht
Crystal structure of the mutant v201f of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMQ is 95.00% similar to enzyme product UMP
3lhu
Crystal structure of the mutant i199f of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMQ is 95.00% similar to enzyme product UMP
3lhv
Crystal structure of the mutant v182a.I199a.V201a of orotidi monophosphate decarboxylase from methanobacterium thermoaut complexed with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMQ is 95.00% similar to enzyme product UMP
3lhw
Crystal structure of the mutant v182a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMQ is 95.00% similar to enzyme product UMP
3lhy
Crystal structure of the mutant i199a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMQ is 95.00% similar to enzyme product UMP
3lhz
Crystal structure of the mutant v201a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMQ is 95.00% similar to enzyme product UMP
3li0
Crystal structure of the mutant r203a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (226 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMQ is 95.45% similar to enzyme product UMP
3li1
Crystal structure of the mutant i218a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMQ is 95.00% similar to enzyme product UMP
3lld
Crystal structure of the mutant s127g of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with 6-azauridine 5'-monophosphate
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine 5'-phosphate
3llf
Crystal structure of the mutant s127p of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with 6-azauridine 5'-monophosphate
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (217 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine 5'-phosphate
3ltp
Crystal structure of orotidine 5'-monophosphate decarboxylas methanobacterium thermoautotrophicum complexed with inhibit
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
3lts
Crystal structure of the mutant v182a,i199a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (214 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
3lty
Crystal structure of the mutant v182a,i218a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (214 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
3lv5
Crystal structure of the mutant i199e of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
3lv6
Crystal structure of the mutant i218f of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
3m1z
Crystal structure of the mutant v182a.V201a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.00% similar to enzyme product UMP
3m41
Crystal structure of the mutant v182a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (207 residues) CATH domain: 3.20.20.70
3m43
Crystal structure of the mutant i199a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (207 residues) CATH domain: 3.20.20.70
3m44
Crystal structure of the mutant v201a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (207 residues) CATH domain: 3.20.20.70
3m47
Crystal structure of the mutant i218a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (209 residues) CATH domain: 3.20.20.70
3m5x
Crystal structure of the mutant v182a,i199a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (212 residues) CATH domain: 3.20.20.70
3m5y
Crystal structure of the mutant v182a,v201a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (212 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group FMT corresponds to enzyme product CO(2)
3m5z
Crystal structure of the mutant v182a,i218a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (213 residues) CATH domain: 3.20.20.70
3mi2
Crystal structure of human orotidine-5'-monophosphate decarb complexed with pyrazofurin monophosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gi|13960142, ok/sw-cl.21, umps. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (257 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PFU is 43.00% similar to enzyme product UMP
3mo7
Crystal structure of human orotidine 5'-monophosphate decarb covalently modified by 2'-fluoro-6-iodo-ump
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gi|13960142, ok/sw-cl.21, umps. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UFT is 90.91% similar to enzyme product UMP
3mw7
Crystal structure of human orotidine 5'-monophosphate decarb complexed with 5-fluoro-ump(produced from 5-fluoro-6-amino-
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gi|13960142, ok/sw-cl.21, umps. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (259 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 5FU is 95.45% similar to enzyme product UMP
3mwa
Crystal structure of plasmodium falciparum orotidine 5'-mono decarboxylase covalently modified by 2-prime-fluoro-6-iodo-
Source: Plasmodium falciparum 3d7. Organism_taxid: 36329. Strain: 3d7. Gene: gi|9310996, pf10_0225. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (330 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UFT is 90.91% similar to enzyme product UMP
3n2m
Crystal structure of plasmodium falciparum orotidine 5'-mono decarboxylase complexed with 5-fluoro-6-amino-ump
Source: Plasmodium falciparum 3d7. Organism_taxid: 36329. Strain: 3d7. Gene: gi|9310996, pf10_0225. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (328 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group FNU is 91.30% similar to enzyme product UMP
  Het Group EDO is 40.00% similar to enzyme product CO(2)
3n34
Crystal structure of plasmodium falciparum orotidine 5'-mono decarboxylase complexed with 5-fluoro-6-amino-ump, produced fluoro-6-azido-ump
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: gi|9310996, pf10_0225. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (327 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group FNU is 91.30% similar to enzyme product UMP
  Het Group EDO is 40.00% similar to enzyme product CO(2)
3n3m
Crystal structure of plasmodium falciparum orotidine 5'-mono decarboxylase complexed with 6-amino-ump
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: gi|9310996, pf10_0225. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (328 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group NUP is 95.45% similar to enzyme product UMP
  Het Group EDO is 40.00% similar to enzyme product CO(2)
3nq6
Crystal structure of the mutant p180a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor 6-azaump
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
3nq7
Crystal structure of the mutant f71a of orotidine 5'-monopho decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3nqa
Crystal structure of the mutant f100a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3nqc
Crystal structure of the mutant i96s of orotidine 5'-monopho decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3nqd
Crystal structure of the mutant i96t of orotidine 5'-monopho decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3nqe
Crystal structure of the mutant l123n of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3nqf
Crystal structure of the mutant l123s of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3nqg
Crystal structure of the mutant v155d of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3nqm
Crystal structure of the mutant v155s of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3p5y
Crystal structure of the mutant t159a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3p5z
Crystal structure of the mutant t159s of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanobacterium thermoautotrophicum. Organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group BMP is 95.45% similar to enzyme product UMP
  Het Group POL is 40.00% similar to enzyme product CO(2)
3p60
Crystal structure of the mutant t159v of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanobacterium thermoautotrophicum. Organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3p61
Crystal structure of the mutant r160a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with inhibitor bmp
Source: Methanobacterium thermoautotrophicum. Organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3pbu
Crystal structure of the mutant i96s of orotidine 5'-monopho decarboxylase from methanobacterium thermoautotrophicum com with 6-azauridine 5'-monophosphate
Source: Methanobacterium thermoautotrophicum. Organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
3pbv
Crystal structure of the mutant i96t of orotidine 5'-monopho decarboxylase from methanobacterium thermoautotrophicum com with 6-azauridine 5'-monophosphate
Source: Methanobacterium thermoautotrophicum. Organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
3pbw
Crystal structure of the mutant l123n of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with 6-azauridine 5'-monophosphate
Source: Methanobacterium thermoautotrophicum. Organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
3pby
Crystal structure of the mutant l123s of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with 6-azauridine 5'-monophosphate
Source: Methanobacterium thermoautotrophicum. Organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
3pc0
Crystal structure of the mutant v155s of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with 6-azauridine 5'-monophosphate
Source: Methanobacterium thermoautotrophicum. Organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
3qez
Crystal structure of the mutant t159v,v182a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3qf0
Crystal structure of the mutant t159v,y206f of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3qmr
Crystal structure of the mutant r160a,v182a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3qms
Crystal structure of the mutant t159v,v182a,y206f of orotidi monophosphate decarboxylase from methanobacterium thermoaut complexed with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3qmt
Crystal structure of the mutant v182a,y206f of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3qw3
Structure of leishmania donovani omp decarboxylase
Source: Leishmania infantum. Organism_taxid: 5671. Gene: linj16.0560. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (250 residues) CATH domain: 3.20.20.70
3r89
Crystal structure of orotidine 5-phosphate decarboxylase fro anaerococcus prevotii dsm 20548
Source: Anaerococcus prevotii. Peptostreptococcus prevotii. Organism_taxid: 525919. Strain: atcc 9321 / dsm 20548 / jcm 6508 / pc1. Gene: pyrf, apre_0783. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (289 residues) CATH domain: 3.20.20.70
3rlu
Crystal structure of the mutant k82a of orotidine 5'-monopho decarboxylase from methanobacterium thermoautotrophicum com with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3rlv
Crystal structure of the mutant y206f of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3ru6
1.8 angstrom resolution crystal structure of orotidine 5'-ph decarboxylase (pyrf) from campylobacter jejuni subsp. Jejun 11168
Source: Campylobacter jejuni subsp. Jejuni. Organism_taxid: 192222. Strain: nctc 11168. Gene: cj0381c, pyrf. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (220 residues) CATH domain: 3.20.20.70
3s9y
Crystal structure of p. Falciparum orotidine 5'-monophosphat decarboxylase complexed with 5-fluoro-6-amino-ump in space produced from 5-fluoro-6-azido-ump
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: gi|9310996, pf10_0225. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (331 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group FNU is 91.30% similar to enzyme product UMP
3sec
Crystal structure of methanothermobacter thermautotrophicus 5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate
Source: Methanothermobacter thermautotrophicus methanococcus thermolithotrophicus. Organism_taxid: 187420. Strain: delta h. Gene: 1470090, mth_129, pyrf. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (214 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PFU is 43.33% similar to enzyme product UMP
3sgu
Crystal structure of methanothermobacter thermautotrophicus 5'-monophosphate decarboxylase covalently modified by 5-flu iodo-ump
Source: Methanothermobacter thermautotrophicus methanococcus thermolithotrophicus. Organism_taxid: 187420. Strain: deltah. Gene: 1470090, mth_129, pyrf. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (213 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 5FU is 95.45% similar to enzyme product UMP
3siz
Crystal structure of the mutant s127a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3sj3
Crystal structure of the mutant r160a.Y206f of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
3ssj
Crystal structure of methanothermobacter thermautotrophicus 5'-monophosphate decarboxylase complexed with 5-fluoro-6-am
Source: Methanothermobacter thermautotrophicus methanococcus thermolithotrophicus. Organism_taxid: 187420. Strain: deltah. Gene: 1470090, mth_129, pyrf. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (214 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group FNU is 91.30% similar to enzyme product UMP
3sw6
Crystal structure of methanothermobacter thermautotrophicus 5'-monophosphate decarboxylase covalently modified by 5-flu azido-ump
Source: Methanothermobacter thermautotrophicus methanococcus thermolithotrophicus. Organism_taxid: 187420. Strain: deltah. Gene: 1470090, mth_129, pyrf. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (214 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 5FU is 95.45% similar to enzyme product UMP
3sy5
Crystal structure of the mutant s127a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with the inhibitor 6azaump
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
3tfx
Crystal structure of orotidine 5'-phosphate decarboxylase fr lactobacillus acidophilus
Source: Lactobacillus acidophilus. Organism_taxid: 1579. Gene: lba1386, pyrf, pyrf/lba1386. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (231 residues) CATH domain: 3.20.20.70
3thq
Crystal structure of methanothermobacter thermautotrophicus 5'-monophosphate decarboxylase complexed with 6-amino-ump
Source: Methanothermobacter thermautotrophicus methanococcus thermolithotrophicus. Organism_taxid: 187420. Strain: deltah. Gene: 1470090, mth_129, pyrf. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (216 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group NUP is 95.45% similar to enzyme product UMP
3tr2
Structure of a orotidine 5'-phosphate decarboxylase (pyrf) f coxiella burnetii
Source: Coxiella burnetii. Organism_taxid: 777. Strain: rsa493. Gene: pyrf, cbu_0531. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (219 residues) CATH domain: 3.20.20.70
3uwq
1.80 angstrom resolution crystal structure of orotidine 5'-p decarboxylase from vibrio cholerae o1 biovar eltor str. N16 complex with uridine-5'-monophosphate (ump)
Source: Vibrio cholerae. Organism_taxid: 666. Strain: vibrio cholerae o1 biovar eltor str. N16961. Gene: pyrf, vc_1911. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (222 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
3v1p
Crystal structure of the mutant q185a of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: delta h. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: 3.20.20.70
3v75
Crystal structure of putative orotidine 5'-phosphate decarbo from streptomyces avermitilis ma-4680
Source: Streptomyces avermitilis. Organism_taxid: 33903. Strain: ma-4680. Gene: pyrf, sav6869, sav_6869. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (285 residues) CATH domain: 3.20.20.70
3ve7
Crystal structure of orotidine 5'-monophosphate decarboxylas metallosphaera sedula complexed with inhibitor bmp
Source: Metallosphaera sedula dsm 5348. Organism_taxid: 399549. Strain: atcc 51363 / dsm 5348. Gene: msed_1966. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (206 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group BMP is 95.45% similar to enzyme product UMP
  Het Group ACY is 75.00% similar to enzyme product CO(2)
3ve9
Crystal structure of orotidine 5'-monophosphate decarboxylas metallosphaera sedula
Source: Metallosphaera sedula. Organism_taxid: 399549. Strain: atcc 51363 / dsm 5348. Gene: msed_1966. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (204 residues) CATH domain: 3.20.20.70
3vi2
Crystal structure analysis of plasmodium falciparum omp deca in complex with inhibitor hmoa
Source: Plasmodium falciparum. Organism_taxid: 5833. Gene: ompdc. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (318 residues) CATH domain: 3.20.20.70
3w07
Atomic resolution structure of orotidine 5'-monophosphate decarboxylase from methanothermobacter thermoautotrophicus ump.
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group U5P corresponds to enzyme product UMP
3wjw
Wild-type orotidine 5'-monophosphate decarboxylase from m. Thermoautotrophicus complexed with 6-methyl-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (215 residues) CATH domain: Unassigned
Bound ligand:   Het Group U6M is 95.45% similar to enzyme product UMP
3wjx
Wild-type orotidine 5'-monophosphate decarboxylase from m. Thermoautotrophicus complexed with 6-amino-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (215 residues) CATH domain: Unassigned
Bound ligand:   Het Group NUP is 95.45% similar to enzyme product UMP
3wjy
Orotidine 5'-monophosphate decarboxylase k72a mutant from m. Thermoautotrophicus complexed with 6-amino-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (215 residues) CATH domain: Unassigned
Bound ligand:   Het Group NUP is 95.45% similar to enzyme product UMP
3wjz
Orotidine 5'-monophosphate decarboxylase d75n mutant from m. Thermoautotrophicus complexed with 6-amino-ump
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (215 residues) CATH domain: Unassigned
Bound ligand:   Het Group NUP is 95.45% similar to enzyme product UMP
3wk0
Wild-type orotidine 5'-monophosphate decarboxylase from m. Thermoautotrophicus complexed with orotidine 5'-monophospha ester
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group O7M is 96.00% similar to enzyme reactant Orotidine
3wk1
Wild-type orotidine 5'-monophosphate decarboxylase from m. Thermoautotrophicus complexed with orotidine 5'-monophospha ester
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (215 residues) CATH domain: Unassigned
Bound ligand:   Het Group O7E is 92.31% similar to enzyme reactant Orotidine
3wk2
Orotidine 5'-monophosphate decarboxylase k72a mutant from m. Thermoautotrophicus complexed with orotidine 5'-monophospha ester
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (215 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group O7M is 96.00% similar to enzyme reactant Orotidine
3wk3
Orotidine 5'-monophosphate decarboxylase k72a mutant from m. Thermoautotrophicus complexed with orotidine 5'-monophospha ester
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (215 residues) CATH domain: Unassigned
Bound ligand:   Het Group O7E is 92.31% similar to enzyme reactant Orotidine
4dbd
Crystal structure of orotidine 5'-monophosphate decarboxylas sulfolobus solfataricus
Source: Sulfolobus solfataricus. Organism_taxid: 555311. Strain: 98/2. Gene: pyrf, ssol_1680. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (210 residues) CATH domain: 3.20.20.70
4dbe
Crystal structure of orotidine 5'-monophosphate decarboxylas sulfolobus solfataricus complexed with inhibitor bmp
Source: Sulfolobus solfataricus. Organism_taxid: 555311. Strain: 98/2. Gene: pyrf, ssol_1680. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (213 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
4fx6
Crystal structure of the mutant v182a.R203a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: M, N (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
4fx8
Crystal structure of the mutant q185a.R203a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (213 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
4fxr
Crystal structure of the mutant t159v.R203a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
4gc4
Crystal structure of the mutant r160a.R203a of orotidine 5'- monophosphate decarboxylase from methanobacterium thermoaut complexed with inhibitor bmp
Source: Methanothermobacter thermautotrophicus delta h. Organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
4hib
Crystal structure of human orotidine 5'-monophosphate decarb complexed with cmp-n4-oh
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps, ok/sw-cl.21. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (256 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group 16B is 86.96% similar to enzyme product UMP
4hkp
Crystal structure of human orotidine 5'-monophosphate decarb complexed with cmp-n3-oxide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: umps, ok/sw-cl.21. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (256 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group TKW is 86.96% similar to enzyme product UMP
4lc6
Crystal structure of the mutant h128q of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (222 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
4lc8
Crystal structure of the mutant h128n of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (222 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group BMP is 95.45% similar to enzyme product UMP
  Het Group EDO is 40.00% similar to enzyme product CO(2)
4lui
Crystal structure of orotidine 5'-monophosphate decarboxylas methanocaldococcus jannaschii
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: pyrf, mj0252. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (204 residues) CATH domain: 3.20.20.70
4luj
Crystal structure of orotidine 5'-monophosphate decarboxylas methanocaldococcus jannaschii complexed with inhibitor bmp
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 10 gene: pyrf, mj0252. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (214 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
4lw7
Crystal structure of the mutant h128s of orotidine 5'-monoph decarboxylase from methanobacterium thermoautotrophicum com with the inhibitor bmp
Source: Methanothermobacter thermautotrophicus organism_taxid: 187420. Strain: atcc 29096 / dsm 1053 / jcm 10044 / nbrc 100330 / d gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: Unassigned
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
4mjz
2.75 angstrom resolution crystal structure of putative oroti monophosphate-decarboxylase from toxoplasma gondii.
Source: Toxoplasma gondii. Organism_taxid: 5811. Strain: me49. Gene: tggt1_010340. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (292 residues) CATH domain: 3.20.20.70
4muz
Crystal structure of orotidine 5'-monophosphate decarboxylas archaeoglobus fulgidus complexed with inhibitor bmp
Source: Archaeoglobus fulgidus. Organism_taxid: 2234. Gene: pyrf, af_0929. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (212 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group BMP is 95.45% similar to enzyme product UMP
4n2y
Crystal structure of orotidine 5'-monophosphate decarboxylas archaeoglobus fulgidus
Source: Archaeoglobus fulgidus. Organism_taxid: 2234. Gene: pyrf, af_0929. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (209 residues) CATH domain: 3.20.20.70
4nt0
Crystal structure of orotidine 5'-monophosphate decarboxylas methanobacterium thermoautotrophicum complexed with 3-deaza 5'-monophosphate
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (213 residues) CATH domain: Unassigned
4nuw
Crystal structure of orotidine 5'-monophosphate decarboxylas methanobacterium thermoautotrophicum complexed with uridine monophosphate
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (219 residues) CATH domain: Unassigned
4nx5
Crystal structure of orotidine 5'-monophosphate decarboxylas methanobacterium thermoautotrophicum complexed with 6-azaur monophosphate
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: Unassigned
Bound ligands:   Het Group UP6 is 80.00% similar to enzyme reactant Orotidine
  Het Group EDO is 40.00% similar to enzyme product CO(2)
4o11
Crystal structure of orotidine 5'-monophosphate decarboxylas methanobacterium thermoautotrophicum complexed with 6-hydro 5'-monophosphate
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: Unassigned
Bound ligands:   Het Group BMP is 95.45% similar to enzyme product UMP
  Het Group EDO is 40.00% similar to enzyme product CO(2)
4o8r
Crystal structure of orotidine 5'-monophosphate decarboxylas methanobacterium thermoautotrophicum complexed with 5,6- dihydrouridine 5'-monophosphate
Source: Methanothermobacter thermautotrophicus organism_taxid: 145262. Gene: pyrf, mth_129. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M (220 residues) CATH domain: Unassigned
Bound ligand:   Het Group H2U corresponds to enzyme product UMP