_EC 4.1.1.22 Histidine decarboxylase. 7 PDB entries  
EC 4.-.-.- Lyases. [3,638 PDB entries]
EC 4.1.-.- Carbon-carbon lyases. [1,237 PDB entries]
EC 4.1.1.- Carboxy-lyases. [740 PDB entries]
EC 4.1.1.22 Histidine decarboxylase. [7 PDB entries]    
1hq6

Reaction: L-histidine = histamine + CO(2).
 


L-histidine
=
histamine
+
CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): L-histidine carboxy-lyase.
Cofactor(s): Pyruvate or pyridoxal 5'-phosphate.
 

Pyruvate
or
pyridoxal 5'-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 7 PDB entries in enzyme class E.C.4.1.1.22

  PDB code Protein
1hq6
Structure of pyruvoyl-dependent histidine decarboxylase at p
Source: Lactobacillus sp.. Organism_taxid: 1593. Strain: 30a. Gene: hdca. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, C, D (66 residues) CATH domain: 4.10.510.10
1ibt
Structure of the d53,54n mutant of histidine decarboxylase a
Source: Lactobacillus sp.. Organism_taxid: 1593. Strain: 30a. Gene: hdca. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (81 residues) CATH domain: 4.10.510.10
1ibu
Structure of the d53,54n mutant of histidine decarboxylase a
Source: Lactobacillus sp.. Organism_taxid: 1593. Strain: 30a. Gene: hdca. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (65 residues) CATH domain: 4.10.510.10
1ibv
Structure of the d53,54n mutant of histidine decarboxylase b histidine methyl ester at-170 c
Source: Lactobacillus sp.. Organism_taxid: 1593. Strain: 30a. Gene: hdca. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (81 residues) CATH domain: 4.10.510.10
Bound ligands:   Het Group PVH is 91.67% similar to enzyme reactant L-histidine
  Het Group PYR is 66.67% similar to enzyme cofactor pyruvate
1ibw
Structure of the d53,54n mutant of histidine decarboxylase b histidine methyl ester at 25 c
Source: Lactobacillus sp.. Organism_taxid: 1593. Strain: 30a. Gene: hdca. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (81 residues) CATH domain: 4.10.510.10
Bound ligands:   Het Group PVH is 91.67% similar to enzyme reactant L-histidine
  Het Group PYR is 66.67% similar to enzyme cofactor pyruvate
1pya
Refined structure of the pyruvoyl-dependent histidine decarboxylase from lactobacillus 30a
Source: Lactobacillus sp. 30a. Organism_taxid: 1593. Strain: 30a. Strain: 30a
Chains: A, B, C, D, E, F (81 residues) CATH domain: 4.10.510.10
4e1o
Human histidine decarboxylase complex with histidine methyl (hme)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hdc. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (477 residues) CATH domains: 1.20.1340.10 3.40.640.10 3.90.1150.10
Bound ligands:   Het Group PVH is 91.67% similar to enzyme reactant L-histidine
  Het Group PLP is 93.75% similar to enzyme cofactor pyridoxal