_EC 3.6.1.1 Inorganic diphosphatase. 88 PDB entries  
EC 3.-.-.- Hydrolases. [21,051 PDB entries]
EC 3.6.-.- Acting on acid anhydrides. [2,179 PDB entries]
EC 3.6.1.- In phosphorous-containing anhydrides. [995 PDB entries]
EC 3.6.1.1 Inorganic diphosphatase. [88 PDB entries]    
117e

Reaction: Diphosphate + H(2)O = 2 phosphate.
 


Diphosphate
+ H(2)O
=
2 × phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Diphosphate phosphohydrolase. Inorganic pyrophosphatase. Pyrophosphate phosphohydrolase.
Comments: Specificity varies with the source and with the activating metal ion. The enzyme from some sources may be identical with Ec 3.1.3.1 or Ec 3.1.3.9.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 88 PDB entries in enzyme class E.C.3.6.1.1

  PDB code Protein
117e
The r78k and d117e active site variants of saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Cellular_location: cytoplasm. Gene: ppa1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (282 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1e6a
Fluoride-inhibited substrate complex of saccharomyces cerevisiae inorganic pyrophosphatase
Source: Saccharomyces cerevisiae. Organism_taxid: 4932. Cellular_location: cytoplasm. Gene: ppa1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (284 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group POP corresponds to enzyme reactant diphosphate
1e9g
Structure of inorganic pyrophosphatase
Source: Saccharomyces cerevisiae. Organism_taxid: 4932. Cellular_location: cytoplasm. Plasmid: pkw9. Gene: ppa1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (284 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1faj
Inorganic pyrophosphatase
Source: Escherichia coli. Organism_taxid: 562
Chain: A (168 residues) CATH domain: 3.90.80.10
1huj
Refined structure of yeast inorganic pyrophosphatase and its k61r mutant
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (281 residues) CATH domain: 3.90.80.10
1huk
Refined structure of yeast inorganic pyrophosphatase and its k61r mutant
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (281 residues) CATH domain: 3.90.80.10
1i40
Structure of inorganic pyrophosphatase
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (175 residues) CATH domain: 3.90.80.10
1i6t
Structure of inorganic pyrophosphatase
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (175 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group POP corresponds to enzyme reactant diphosphate
1i74
Streptococcus mutans inorganic pyrophosphatase
Source: Streptococcus mutans. Organism_taxid: 1309. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (309 residues) CATH domain: 3.90.1640.10
1igp
X-ray crystallographic studies of recombinant inorganic pyrophosphatase from escherichia coli
Source: Escherichia coli. Organism_taxid: 562
Chain: A (175 residues) CATH domain: 3.90.80.10
1ino
Recombinant inorganic pyrophosphatase from escherichia coli
Source: Escherichia coli. Organism_taxid: 562. Strain: jm109. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (175 residues) CATH domain: 3.90.80.10
1ipw
Inorganic pyrophosphatase from escherichia coli with three m ions
Source: Escherichia coli. Organism_taxid: 562
Chains: A, B (168 residues) CATH domain: 3.90.80.10
1jfd
Structure of inorganic pyrophosphatase
Source: Escherichia coli. Organism_taxid: 562. Strain: jm109. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (175 residues) CATH domain: 3.90.80.10
1k20
Inorganic pyrophosphatase (family ii) from streptococcus gor 1.5 a resolution
Source: Streptococcus gordonii. Organism_taxid: 1302. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (310 residues) CATH domain: 3.90.1640.10
1k23
Inorganic pyrophosphatase (family ii) from bacillus subtilis
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (307 residues) CATH domain: 3.90.1640.10
1m38
Structure of inorganic pyrophosphatase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932
Chains: A, B (282 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1mjw
Structure of inorganic pyrophosphatase mutant d42n
Source: Escherichia coli. Organism_taxid: 562. Strain: jm109. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (175 residues) CATH domain: 3.90.80.10
1mjx
Structure of inorganic pyrophosphatase mutant d65n
Source: Escherichia coli. Organism_taxid: 562. Strain: jm109. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (175 residues) CATH domain: 3.90.80.10
1mjy
Structure of inorganic pyrophosphatase mutant d70n
Source: Escherichia coli. Organism_taxid: 562. Strain: jm109. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (175 residues) CATH domain: 3.90.80.10
1mjz
Structure of inorganic pyrophosphatase mutant d97n
Source: Escherichia coli. Organism_taxid: 562. Strain: jm109. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (175 residues) CATH domain: 3.90.80.10
1obw
Structure of inorganic pyrophosphatase
Source: Escherichia coli. Organism_taxid: 562. Strain: jm109. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (175 residues) CATH domain: 3.90.80.10
1pyp
X-ray diffraction study of inorganic pyrophosphatase from baker,s yeast at the 3 angstroms resolution (russian)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932
Chains: A, B (281 residues) CATH domain: 3.90.80.10
1qez
Sulfolobus acidocaldarius inorganic pyrophosphatase: an archael pyrophosphatase.
Source: Sulfolobus acidocaldarius. Organism_taxid: 2285. Atcc: dsm 639. Collection: dsm 639. Cellular_location: cytoplasm. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Other_details: german collection of microorganisms (dsm)
Chains: A, B, C, D, E, F (170 residues) CATH domain: 3.90.80.10
1sxv
1.3a crystal structure of rv3628, mycobacterium tuberculosis pyrophosphatase (ppase) at ph5.0
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: ppa, rv3628, mt3730, mtcy15c10.24, mb3652. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (160 residues) CATH domain: 3.90.80.10
1twl
Inorganic pyrophosphatase from pyrococcus furiosus pfu-26409
Source: Pyrococcus furiosus. Organism_taxid: 2261. Gene: ppa, pf0257. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (172 residues) CATH domain: 3.90.80.10
1ude
Crystal structure of the inorganic pyrophosphatase from the hyperthermophilic archaeon pyrococcus horikoshii ot3
Source: Pyrococcus horikoshii. Organism_taxid: 53953. Gene: ppa. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (168 residues) CATH domain: 3.90.80.10
1wcf
1.54 a crystal structure of rv3628, mycobacterium tuberculosis inorganic pyrophosphatase (ppase) at ph7.0
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (162 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1wgi
Structure of inorganic pyrophosphatase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ppa1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (283 residues) CATH domain: 3.90.80.10
1wgj
Structure of inorganic pyrophosphatase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ppa1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (282 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1wpm
Structure of bacillus subtilis inorganic pyrophosphatase
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (307 residues) CATH domain: 3.90.1640.10
1wpn
Crystal structure of the n-terminal core of bacillus subtilis inorganic pyrophosphatase
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (187 residues) CATH domain: 3.90.1640.10
1wpp
Structure of streptococcus gordonii inorganic pyrophosphatas
Source: Streptococcus gordonii. Organism_taxid: 29390. Strain: str. Challis. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (310 residues) CATH domain: 3.90.1640.10
1ygz
Crystal structure of inorganic pyrophosphatase from helicoba pylori
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: 26695. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (172 residues) CATH domain: 3.90.80.10
1ypp
Acid anhydride hydrolase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Cell_line: s2
Chains: A, B (282 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2au6
Crystal structure of catalytic intermediate of inorganic pyrophosphatase
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (175 residues) CATH domain: 3.90.80.10
Bound ligands:   Het Group POP corresponds to enzyme reactant diphosphate
  Het Group PO4 corresponds to enzyme product phosphate
2au7
The r43q active site variant of e.Coli inorganic pyrophospha
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (175 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2au8
Catalytic intermediate structure of inorganic pyrophosphatas
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (175 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2au9
Inorganic pyrophosphatase complexed with substrate
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (175 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group POP corresponds to enzyme reactant diphosphate
2auu
Inorganic pyrophosphatase complexed with magnesium pyrophosp fluoride
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (175 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group POP corresponds to enzyme reactant diphosphate
2bqx
Inorganic pyrophosphatase from the pathogenic bacterium helicobacter pylori-kinetic and structural properties
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: 26695. Atcc: 700392d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (166 residues) CATH domain: 3.90.80.10
2bqy
Inorganic pyrophosphatase from the pathogenic bacterium helicobacter pylori-kinetic and structural properties
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: 26695. Atcc: 700392d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (170 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group POP corresponds to enzyme reactant diphosphate
2eb0
Crystal structure of methanococcus jannaschii putative famil inorganic pyrophosphatase
Source: Methanocaldococcus jannaschii. Organism_taxid: 243232. Strain: dsm 2661. Gene: mj0608. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (304 residues) CATH domain: 3.90.1640.10
2eip
Inorganic pyrophosphatase
Source: Escherichia coli. Organism_taxid: 562
Chains: A, B (168 residues) CATH domain: 3.90.80.10
2enx
Structure of the family ii inorganic pyrophosphatase from streptococcus agalactiae at 2.8 resolution
Source: Streptococcus agalactiae. Organism_taxid: 205921. Strain: a909. Gene: ppac. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (310 residues) CATH domain: 3.90.1640.10
Bound ligand:   Het Group 2PN is 40.00% similar to enzyme product phosphate
2haw
Crystal structure of family ii inorganic pyrophosphatase in with pnp
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (307 residues) CATH domain: 3.90.1640.10
Bound ligand:   Het Group 2PN is 40.00% similar to enzyme product phosphate
2hdo
Crystal structure of putative phosphoglycolate phosphatase (np_784602.1) from lactobacillus plantarum at 1.50 a resolu
Source: Lactobacillus plantarum. Organism_taxid: 1590. Gene: np_784602.1, gph1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (207 residues) CATH domains: 3.40.50.1000 1.10.150.240
2ihp
Yeast inorganic pyrophosphatase with magnesium and phosphate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ipp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (275 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2ik0
Yeast inorganic pyrophosphatase variant e48d with magnesium and phosphate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ipp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (271 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2ik1
Yeast inorganic pyrophosphatase variant y93f with magnesium and phosphate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ipp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (273 residues) CATH domain: 3.90.80.10
2ik2
Yeast inorganic pyrophosphatase variant d115e with magnesium and phosphate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ipp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (276 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2ik4
Yeast inorganic pyrophosphatase variant d117e with magnesium and phosphate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ipp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (273 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2ik6
Yeast inorganic pyrophosphatase variant d120e with magnesium and phosphate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ipp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (268 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2ik7
Yeast inorganic pyrophosphatase variant d120n with magnesium and phosphate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ipp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (277 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2ik9
Yeast inorganic pyrophosphatase variant d152e with magnesium and phosphate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ipp1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (278 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2iw4
Crystal structure of basillus subtilis family ii inorganic pyrophosphatase mutant, h98q, in complex with pnp
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (308 residues) CATH domain: 3.90.1640.10
Bound ligand:   Het Group 2PN is 40.00% similar to enzyme product phosphate
2prd
Crystal structure of inorganic pyrophosphatase from thermus thermophilus
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8
Chain: A (174 residues) CATH domain: 3.90.80.10
2uxs
2.7a crystal structure of inorganic pyrophosphatase (rv3628) from mycobacterium tuberculosis at ph 7.5
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (160 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2x4d
Crystal structure of human phospholysine phosphohistidine inorganic pyrophosphate phosphatase lhpp
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-prare2.
Chains: A, B (270 residues) CATH domains: 3.40.50.1000 3.40.50.1000
Bound ligand:   Het Group POP corresponds to enzyme product phosphate
3d53
2.2 a crystal structure of inorganic pyrophosphatase from ri prowazekii
Source: Rickettsia prowazekii. Organism_taxid: 272947. Strain: madrid e. Gene: ppa, rp589. Expressed in: escherichia coli.
Chains: A, B, C, D, E, F (170 residues) CATH domain: 3.90.80.10
3d63
Crystal structure of inorganic pyrophosphatase from burkhold pseudomallei
Source: Burkholderia pseudomallei. Organism_taxid: 320372. Strain: 1710b. Gene: ppa, burps1710b_1237. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (173 residues) CATH domain: 3.90.80.10
3eiy
Crystal structure of inorganic pyrophosphatase from burkhold pseudomallei with bound pyrophosphate
Source: Burkholderia pseudomallei 1710b. Organism_taxid: 320372. Gene: ppa, burps1710b_1237. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (174 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group POP corresponds to enzyme reactant diphosphate
3eiz
Crystal structure of inorganic pyrophosphatase from burkhold pseudomallei, h32 crystal form
Source: Burkholderia pseudomallei 1710b. Organism_taxid: 320372. Gene: ppa, burps1710b_1237. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (182 residues) CATH domain: 3.90.80.10
3ej0
Crystal structure of inorganic pyrophosphatase from burkhold pseudomallei with bound n-(pyridin-3-ylmethyl) aniline, h32 form
Source: Burkholderia pseudomallei 1710b. Organism_taxid: 320372. Gene: ppa, burps1710b_1237. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (173 residues) CATH domain: 3.90.80.10
3ej2
Crystal structure of inorganic pyrophosphatase from burkhold pseudomallei with bound 5-amino-1-(4-chlorophenyl)-1h-pyraz carbonitrile, h32 crystal form
Source: Burkholderia pseudomallei 1710b. Organism_taxid: 320372. Gene: ppa, burps1710b_1237. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (182 residues) CATH domain: 3.90.80.10
3emj
2.2 a crystal structure of inorganic pyrophosphatase from rickettsia prowazekii (p21 form)
Source: Rickettsia prowazekii. Organism_taxid: 782. Strain: madrid e. Gene: ppa, rp589. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (167 residues) CATH domain: 3.90.80.10
3fq3
Crystal structure of inorganic phosphatase from brucella mel
Source: Brucella melitensis biovar abortus 230 organism_taxid: 359391. Strain: biovar abortus 2308. Gene: ppa, bab1_1993. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (174 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
3gvf
1.7 angstrom crystal structure of inorganic pyrophosphatase burkholderia pseudomallei bound with phosphate
Source: Burkholderia pseudomallei 1710b. Organism_taxid: 320372. Strain: 1710b. Gene: ppa, burps1710b_1237. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (174 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
3i4q
Structure of a putative inorganic pyrophosphatase from the o degrading bacterium oleispira antarctica
Source: Oleispira antarctica. Organism_taxid: 188908. Gene: olei03685. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (170 residues) CATH domain: 3.90.80.10
3i98
X-ray crystallographic structure of inorganic pyrophosphatas from archaeon thermococcus thioreducens
Source: Thermococcus thioreducens. Organism_taxid: 277988. Strain: ogl-20. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (175 residues) CATH domain: 3.90.80.10
3l2b
Crystal structure of the cbs and drtgg domains of the regulatory region of clostridium perfringens pyrophosphatase complexed with activator, diadenosine tetraphosphate
Source: Clostridium perfringens. Organism_taxid: 195102. Strain: str. 13. Gene: cpe2055. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (233 residues) CATH domains: 3.10.580.10 3.40.1390.20
3l31
Crystal structure of the cbs and drtgg domains of the regulatory region of clostridium perfringens pyrophosphatase complexed with the inhibitor, amp
Source: Clostridium perfringens. Organism_taxid: 195102. Strain: str. 13. Gene: cpe2055. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (234 residues) CATH domains: 3.10.580.10 3.40.1390.20
3ld3
Crystal structure of inorganic phosphatase from anaplasma phagocytophilum at 1.75a resolution
Source: Anaplasma phagocytophilum. Organism_taxid: 212042. Strain: hz. Gene: ppa, aph_1101. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (171 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
3lo0
Crystal structure of inorganic pyrophosphatase from ehrlichia chaffeensis
Source: Ehrlichia chaffeensis. Organism_taxid: 205920. Strain: arkansas. Gene: ppa, ech_1014. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (156 residues) CATH domain: 3.90.80.10
3q3l
The neutron crystallographic structure of inorganic pyrophos from thermococcus thioreducens
Source: Thermococcus thioreducens. Organism_taxid: 277988. Strain: ogl-20. Gene: tt-ippase. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (175 residues) CATH domain: 3.90.80.10
3q46
Magnesium activated inorganic pyrophosphatase from thermococ thioreducens bound to hydrolyzed product at 0.99 angstrom r
Source: Thermococcus thioreducens. Organism_taxid: 277988. Strain: ogl-20. Gene: tt-ippase. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (178 residues) CATH domain: 3.90.80.10
3q4w
The structure of archaeal inorganic pyrophosphatase in compl substrate
Source: Thermococcus thioreducens. Organism_taxid: 277988. Strain: ogl-20. Gene: tt-ippase. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (175 residues) CATH domain: 3.90.80.10
3q5v
The structure of inorganic pyrophosphatase from thermococcus thioreducens in complex with magnesium and sulfate
Source: Thermococcus thioreducens. Organism_taxid: 277988. Strain: ogl-20. Gene: tt-ippase. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (178 residues) CATH domain: 3.90.80.10
3q9m
The structure archaeal inorganic pyrophosphatase in complex pyrophosphate
Source: Thermococcus thioreducens. Organism_taxid: 277988. Strain: ogl-20. Gene: tt-ippase. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C (175 residues) CATH domain: 3.90.80.10
3r5u
The structure of manganese bound thermococcus thioreducens i pyrophosphatase
Source: Thermococcus thioreducens. Organism_taxid: 277988. Strain: ogl-20. Gene: tt-ippase. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (175 residues) CATH domain: 3.90.80.10
3r5v
The structure of calcium bound thermococcus thioreducens ino pyrophosphatase at 298k
Source: Thermococcus thioreducens. Organism_taxid: 277988. Strain: ogl-20. Gene: tt-ippase. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (175 residues) CATH domain: 3.90.80.10
3r6e
The structure of thermococcus thioreducens' inorganic pyroph bound to sulfate
Source: Thermococcus thioreducens. Organism_taxid: 277988. Strain: ogl-20. Gene: tt-ippase. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (175 residues) CATH domain: 3.90.80.10
3sw5
Crystal structure of inorganic pyrophosphatase from bartonel henselae
Source: Bartonella henselae. Organism_taxid: 38323. Gene: ppa, bh01690. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (173 residues) CATH domain: 3.90.80.10
3tr4
Structure of an inorganic pyrophosphatase (ppa) from coxiell
Source: Coxiella burnetii. Organism_taxid: 227377. Strain: rsa493. Gene: cbu_0628, ppa. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (169 residues) CATH domain: 3.90.80.10
4a01
Crystal structure of the h-translocating pyrophosphatase
Source: Vigna radiata. Organism_taxid: 157791. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932.
Chains: A, B (740 residues) CATH domain: Unassigned
Bound ligand:   Het Group 2PN is 40.00% similar to enzyme product phosphate
4av3
Crystal structure of thermotoga maritima sodium pumping memb integral pyrophosphatase with metal ions in active site
Source: Thermotoga maritima. Organism_taxid: 2336. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932.
Chains: A, B (694 residues) CATH domain: Unassigned
4av6
Crystal structure of thermotoga maritima sodium pumping memb integral pyrophosphatase at 4 a in complex with phosphate a magnesium
Source: Thermotoga maritima. Organism_taxid: 2336. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932.
Chains: A, B (655 residues) CATH domain: Unassigned
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
4ecp
X-ray crystal structure of inorganic pyrophosphate ppa from mycobacterium leprae
Source: Mycobacterium leprae. Organism_taxid: 1769. Gene: ppa, ml0210, mlcb2548.21. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (160 residues) CATH domain: 3.90.80.10
8prk
The r78k and d117e active site variants of saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Cellular_location: cytoplasm. Gene: ppa1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (282 residues) CATH domain: 3.90.80.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate