_EC 3.5.5.8 Thiocyanate hydrolase. 6 PDB entries  
EC 3.-.-.- Hydrolases. [20,896 PDB entries]
EC 3.5.-.- Acting on carbon-nitrogen bonds, other than peptide bonds. [1,572 PDB entries]
EC 3.5.5.- In nitriles. [10 PDB entries]
EC 3.5.5.8 Thiocyanate hydrolase. [6 PDB entries]    
2dd4

Reaction: Thiocyanate + 2 H(2)O = carbonyl sulfide + NH(3) + HO(-).
 


Thiocyanate
+ 2 × H(2)O
=
carbonyl sulfide
+ NH(3)
+ HO(-)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: The enzyme from Thiobacillus thioparus catalyzes the first step in the degradation of thiocyanate.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 6 PDB entries in enzyme class E.C.3.5.5.8

  PDB code Protein
2dd4
Thiocyanate hydrolase (scnase) from thiobacillus thioparus recombinant apo-enzyme
Source: Thiobacillus thioparus. Organism_taxid: 931. Strain: thi115. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, D, E, F, G, H, I, J, K, L (118 residues) CATH domain: 2.30.30.50
2dd5
Thiocyanate hydrolase (scnase) from thiobacillus thioparus native holo-enzyme
Source: Thiobacillus thioparus. Organism_taxid: 931. Strain: thi 115. Strain: thi 115
Chains: B, C, E, F, G, I, J, K, L (152 residues) CATH domain: Unassigned
2dxb
Recombinant thiocyanate hydrolase comprising partially-modif centers
Source: Thiobacillus thioparus. Organism_taxid: 931. Strain: thi115. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, C, D, F, G, H, I, J, K, L, N, O, Q, R, S, T, V, X (118 residues) CATH domain: 2.30.30.50
2dxc
Recombinant thiocyanate hydrolase, fully-matured form
Source: Thiobacillus thioparus. Organism_taxid: 931. Strain: thi115. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: B, C, D, E, F, G, H, J, K, L (152 residues) CATH domain: Unassigned
2zzd
Recombinant thiocyanate hydrolase, air-oxidized form of holo-enzyme
Source: Thiobacillus thioparus. Organism_taxid: 931. Strain: thi115. Gene: scna. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: scnb. Gene: scnc.
Chains: B, C, D, G, H, I, J, K, L (153 residues) CATH domain: Unassigned
3vyg
Crystal structure of thiocyanate hydrolase mutant r136w
Source: Thiobacillus thioparus. Organism_taxid: 931. Gene: scna. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: scnb. Gene: scnc. Expression_system_taxid: 562
Chains: A, B, D, E, F, G, H, I, J, K, L (120 residues) CATH domain: 2.30.30.50