_EC 3.5.3.12 Agmatine deiminase. 7 PDB entries  
EC 3.-.-.- Hydrolases. [21,057 PDB entries]
EC 3.5.-.- Acting on carbon-nitrogen bonds, other than peptide bonds. [1,666 PDB entries]
EC 3.5.3.- In linear amidines. [165 PDB entries]
EC 3.5.3.12 Agmatine deiminase. [7 PDB entries]    
1vkp

Reaction: Agmatine + H(2)O = N-carbamoylputrescine + NH(3).
 


Agmatine
+ H(2)O
=
N-carbamoylputrescine
+ NH(3)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: The plant enzyme also catalyzes the reactions of Ec 2.1.3.3, Ec 2.1.3.6 and Ec 2.7.2.2, thus functioning as a putrescine synthase, converting agmatine and ornithine into putrescine and citrulline, respectively.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 7 PDB entries in enzyme class E.C.3.5.3.12

  PDB code Protein
1vkp
X-ray structure of gene product from arabidopsis thaliana at5g08170, agmatine iminohydrolase
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: at5g08170. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (365 residues) CATH domain: 3.75.10.10
2ewo
X-ray structure of putative agmatine deiminase q8dw17, northeast structural genomics target smr6.
Source: Streptococcus mutans. Organism_taxid: 1309. Gene: agua. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (362 residues) CATH domain: 3.75.10.10
2j2t
Agmatine deiminase from enterococcus faecalis covalently linked with a reaction intermediate
Source: Expressed in: escherichia coli. Enterococcus faecalis. Strain: sd10
Chains: A, B, C, D, E, F, G, H (366 residues) CATH domain: 3.75.10.10
2jer
Agmatine deiminase of enterococcus faecalis catalyzing its reaction.
Source: Enterococcus faecalis. Organism_taxid: 1351. Strain: sd10. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (366 residues) CATH domain: 3.75.10.10
2q3u
Ensemble refinement of the protein crystal structure of gene from arabidopsis thaliana at5g08170, agmatine iminohydrolas
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Strain: cv. Columbia. Gene: aih, at5g08170, t22d6.110. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (365 residues) CATH domain: 3.75.10.10
3h7c
Crystal structure of arabidopsis thaliana agmatine deiminase from cell free expression
Source: Arabidopsis thaliana. Mouse-ear cress,thale-cress. Organism_taxid: 3702. Strain: columbia. Gene: aih, at5g08170, emb1873, t22d6.110. Expressed in: cell-free synthesis. Other_details: wheat germ
Chain: X (369 residues) CATH domain: 3.75.10.10
3h7k
Crystal structure of arabidopsis thaliana agmatine deiminase with a covalently bound reaction intermediate
Source: Arabidopsis thaliana. Mouse-ear cress,thale-cress. Organism_taxid: 3702. Strain: columbia. Gene: aih, at5g08170, emb1873, t22d6.110. Expressed in: cell-free synthesis. Other_details: wheat germ
Chain: A (367 residues) CATH domain: 3.75.10.10