_EC 3.5.1.9 Arylformamidase. 9 PDB entries  
EC 3.-.-.- Hydrolases. [22,330 PDB entries]
EC 3.5.-.- Acting on carbon-nitrogen bonds, other than peptide bonds. [1,811 PDB entries]
EC 3.5.1.- In linear amides. [633 PDB entries]
EC 3.5.1.9 Arylformamidase. [9 PDB entries]    
1vkh

Pathway: Tryptophan Catabolism
Reaction: N-formyl-L-kynurenine + H(2)O = formate + L-kynurenine.
 


N-formyl-L-kynurenine
+ H(2)O
=
formate
+
L-kynurenine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Formylase. Formylkynureninase. Kynurenine formamidase.
Comments: Also acts on other aromatic formylamines.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 9 PDB entries in enzyme class E.C.3.5.1.9

  PDB code Protein
1vkh
Crystal structure of a putative serine hydrolase (ydr428c) f saccharomyces cerevisiae at 1.85 a resolution
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ydr428c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (261 residues) CATH domain: 3.40.50.1820
4co9
Crystal structure of kynurenine formamidase from bacillus anthracis
Source: Bacillus anthracis. Organism_taxid: 198094. Strain: ames. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (207 residues) CATH domain: 3.50.30.50
Bound ligand:   Het Group GXT is 40.00% similar to enzyme product Formate
4coa
Crystal structure of kynurenine formamidase from bacillus anthracis complexed with 2-aminoacetophenone.
Source: Bacillus anthracis. Organism_taxid: 198094. Strain: ames. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (207 residues) CATH domain: 3.50.30.50
Bound ligand:   Het Group VNJ is 66.67% similar to enzyme product L-kynurenine
4cob
Crystal structure kynurenine formamidase from pseudomonas ae
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 15692. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss.
Chains: A, B (206 residues) CATH domain: 3.50.30.50
4cog
Crystal structure of kynurenine formamidase from burkholderia cenocepacia
Source: Burkholderia cenocepacia. Organism_taxid: 216591. Strain: j2315. Atcc: baa-245. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss.
Chains: A, B, C, D (207 residues) CATH domain: 3.50.30.50
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product Formate
4cz1
Crystal structure of kynurenine formamidase from bacillus anthracis complexed with 2-aminoacetophenone.
Source: Bacillus anthracis str. Ames. Organism_taxid: 198094. Gene: kynb. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (207 residues) CATH domain: 3.50.30.50
Bound ligand:   Het Group VNJ is 66.67% similar to enzyme product L-kynurenine
4e11
Crystal structure of kynurenine formamidase from drosophila melanogaster
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg9542, dmel_cg9542. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (300 residues) CATH domain: 3.40.50.1820
Bound ligand:   Het Group BME is 40.00% similar to enzyme product Formate
4e14
Crystal structure of kynurenine formamidase conjugated with phenylmethylsulfonyl fluoride
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg9542, dmel_cg9542. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (300 residues) CATH domain: 3.40.50.1820
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product Formate
4e15
Crystal structure of kynurenine formamidase conjugated with inhibitor
Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: cg9542, dmel_cg9542. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (302 residues) CATH domain: 3.40.50.1820
Bound ligand:   Het Group EDO is 40.00% similar to enzyme product Formate