_EC Phthalyl amidase. 0 PDB entries  
EC 3.-.-.- Hydrolases. [22,079 PDB entries]
EC 3.5.-.- Acting on carbon-nitrogen bonds, other than peptide bonds. [1,723 PDB entries]
EC 3.5.1.- In linear amides. [618 PDB entries]
EC Phthalyl amidase. [-]    

Reaction: A phthalylamide + H(2)O = phthalic acid + a substituted amine.

+ H(2)O
phthalic acid
substituted amine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): o-phthalyl amidase.
Comments: Phthalyl is used to mean 2-carboxybenzoyl. The enzyme from Xanthobacter agilis hydrolyzes phthalylated amino acids, peptides, beta-lactams, aromatic and aliphatic amines. The substituent on nitrogen may be an alkyl group, but may also be complex, giving an amino acid or peptide derivative. Substitutions on the phthalyl ring include 6-F, 6-NH(2), 3-OH, and a nitrogen in the aromatic ring ortho to the carboxy group attached to the amine.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.