_EC 3.5.1.52 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase. 17 PDB entries  
EC 3.-.-.- Hydrolases. [21,057 PDB entries]
EC 3.5.-.- Acting on carbon-nitrogen bonds, other than peptide bonds. [1,666 PDB entries]
EC 3.5.1.- In linear amides. [596 PDB entries]
EC 3.5.1.52 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase. [17 PDB entries]    
1pgs

Reaction: Hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue.
Other name(s): Glycopeptidase. Glycopeptide N-glycosidase. N-glycanase. N-oligosaccharide glycopeptidase.
Comments: Does not act on (GlcNAc)-Asn, because it requires the presence of more than two amino-acid residues in the substrate (cf. Ec 3.5.1.26). Formerly Ec 3.2.2.18.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 17 PDB entries in enzyme class E.C.3.5.1.52

  PDB code Protein
1pgs
The three-dimensional structure of pngase f, a glycosylasparaginase from flavobacterium meningosepticum
Source: Elizabethkingia meningoseptica. Organism_taxid: 238
Chain: A (311 residues) CATH domains: 2.60.120.230 2.60.120.230
1pnf
Pngase f complex with di-n-acetylchitobiose
Source: Elizabethkingia meningoseptica. Organism_taxid: 238
Chain: A (314 residues) CATH domains: 2.60.120.230 2.60.120.230
1png
Crystal structure of peptide-n(4)-(n-acetyl-beta-d- glucosaminyl) asparagine amidase at 2.2 angstroms resolution
Source: Elizabethkingia meningoseptica. Organism_taxid: 238
Chain: A (310 residues) CATH domains: 2.60.120.230 2.60.120.230
1x3w
Structure of a peptide:n-glycanase-rad23 complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (320 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned
1x3z
Structure of a peptide:n-glycanase-rad23 complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was chemically synthesized
Chain: A (320 residues) CATH domains: Unassigned Unassigned Unassigned 2.20.25.10
2ccq
The pub domain functions as a p97 binding module in human peptide n-glycanase.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (99 residues) CATH domain: Unassigned
2cm0
The pub domain functions as a p97 binding module in human peptide n-glycanase.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (99 residues) CATH domain: Unassigned
2d5u
Solution structure of the n-terminal portion of the pub domain of mouse peptide:n-glycanase
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (124 residues) CATH domain: Unassigned
2f4m
The mouse pngase-hr23 complex reveals a complete remodulatio protein-protein interface compared to its yeast orthologs
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rad23b, mhr23b.
Chain: A (295 residues) CATH domains: Unassigned 2.20.25.10
2f4o
The mouse pngase-hr23 complex reveals a complete remodulatio protein-protein interface compared to its yeast orthologs
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rad23b, mhr23b. Synthetic: yes
Chain: A (290 residues) CATH domains: Unassigned Unassigned
2g9f
Crystal structure of intein-tagged mouse pngasE C-terminal d
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ngly1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (180 residues) CATH domain: Unassigned
2g9g
Crystal structure of his-tagged mouse pngasE C-terminal doma
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ngly1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (189 residues) CATH domain: Unassigned
2hpj
Crystal structure of the pub domain of mouse pngase
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ngly1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (99 residues) CATH domain: Unassigned
2hpl
Crystal structure of the mouse p97/pngase complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ngly1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: chemically synthesized. Occurs naturally in musculus (mouse)
Chain: A (100 residues) CATH domain: Unassigned
2i74
Crystal structure of mouse peptide n-glycanasE C-terminal do complex with mannopentaose
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: ngly1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (180 residues) CATH domain: Unassigned
3esw
Complex of yeast pngase with glcnac2-iac.
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: png1, ypl096w. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rad23, sygp-orf29, yel037c.
Chain: A (333 residues) CATH domains: Unassigned 2.20.25.10
3pms
Recombinant peptide: n-glycanase f (pngase f)
Source: Elizabethkingia meningoseptica. Chryseobacterium meningosepticum. Organism_taxid: 238. Strain: cdc 3552. Gene: png. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (312 residues) CATH domains: 2.60.120.230 2.60.120.230