_EC 3.4.24.84 Ste24 endopeptidase. 3 PDB entries  
EC 3.-.-.- Hydrolases. [21,295 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [6,892 PDB entries]
EC 3.4.24.- Metalloendopeptidases. [615 PDB entries]
EC 3.4.24.84 Ste24 endopeptidase. [3 PDB entries]    
2ypt

Reaction: The peptide bond hydrolyzed can be designated -C-|-A-A-X in which C is an S-isoprenylated cysteine residue, A is usually aliphatic and x is the C-terminal residue of the substrate protein, and may be any of several amino acids.
Other name(s): Caax prenyl protease 1. Prenyl protein-specific endoprotease 1.
Cofactor(s): Zn(2+).
Comments: One of two enzymes that can catalyze this processing step for mating a-factor in Saccharomyces cerevisiae. Subsequently, the S-isoprenylated cysteine residue that forms the new C-terminus is methyl-esterified and forms a hydrophobic membrane- anchor. Belongs to peptidase family M48.
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There are 3 PDB entries in enzyme class E.C.3.4.24.84

  PDB code Protein
2ypt
Crystal structure of the human nuclear membrane zinc metallo zmpste24 mutant (e336a) in complex with a synthetic csim tetrapeptide from thE C-terminus of prelamin a
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Synthetic: yes. Organism_taxid: 9606
Chains: A, B, D, E (424 residues) CATH domains: Unassigned 3.30.2010.10
4aw6
Crystal structure of the human nuclear membrane zinc metallo zmpste24 (face1)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Chains: A, B, D, E (427 residues) CATH domains: Unassigned 3.30.2010.10
4il3
Crystal structure of s. Mikatae ste24p
Source: Saccharomyces mikatae. Organism_taxid: 114525. Strain: ifo 1815t. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932.
Chains: A, B (422 residues) CATH domains: Unassigned 3.30.2010.10