_EC 3.4.24.55 Pitrilysin. 1 PDB entries  
EC 3.-.-.- Hydrolases. [20,896 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [6,843 PDB entries]
EC 3.4.24.- Metalloendopeptidases. [613 PDB entries]
EC 3.4.24.55 Pitrilysin. [1 PDB entries]    
1q2l

Reaction: Preferential cleavage of 16-Tyr-|-Leu-17 and 25-Phe-|-Tyr-26 bonds of oxidized insulin B chain. Also acts on other substrates of Mw less than 7 kDa such as insulin and glucagon.
Other name(s): Protease Iii. Protease Pi.
Cofactor(s): Zinc.
Comments: From the periplasmic space of Escherichia coli. Inhibited by Edta and 1,10-phenanthroline; not thiol dependent. Belongs to peptidase family M16. Formerly Ec 3.4.99.44.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.3.4.24.55

  PDB code Protein
1q2l
Crystal structure of pitrilysin
Source: Escherichia coli str. K12 substr.. Organism_taxid: 316407. Strain: w3110. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (937 residues) CATH domains: 3.30.830.10 3.30.830.10 3.30.830.10 3.30.830.10