_EC 3.4.24.18 Meprin A. 0 PDB entries  
EC 3.-.-.- Hydrolases. [21,051 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [6,852 PDB entries]
EC 3.4.24.- Metalloendopeptidases. [610 PDB entries]
EC 3.4.24.18 Meprin A. [-]    

Reaction: Hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues.
Other name(s): Endopeptidase-2.
Cofactor(s): Zn(2+).
Comments: A membrane-bound metalloendopeptidase of rat and mouse kidney and intestinal brush borders, and salivary ducts. Differences from Ec 3.4.24.11 include insensitivity to phosphoramidon and thiorphan. PABA-peptide hydrolase is a very similar enzyme found in human intestinal microvilli. Belongs to peptidase family M12A.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.3.4.24.18