_EC 3.4.21.90 Togavirin. 34 PDB entries  
EC 3.-.-.- Hydrolases. [21,057 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [6,846 PDB entries]
EC 3.4.21.- Serine endopeptidases. [2,535 PDB entries]
EC 3.4.21.90 Togavirin. [34 PDB entries]    
1dyl

Reaction: Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Other name(s): NsP2 proteinase. Sindbis virus protease.
Comments: Once released, the core protein does not retain catalytic activity. Belongs to peptidase family S3.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 34 PDB entries in enzyme class E.C.3.4.21.90

  PDB code Protein
1dyl
9 angstrom resolution cryo-em reconstruction structure of semliki forest virus (sfv) and fitting of the capsid protein structure in the em density
Source: Semliki forest virus. Sfv. Organism_taxid: 11033. Cell_line: baby hamster kidney 21. Cellular_location: extracellular
Chains: A, B, C, D (149 residues)
1ep5
Crystal structure of the conserved core domain of venezualan equine encephalitis capsid protein
Source: Venezuelan equine encephalitis virus. Organism_taxid: 11036. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: B, A, C (157 residues) CATH domains: 2.40.10.10 2.40.10.10
1ep6
Crystal structure of the conserved core domain of venezualan equine encephalitis capsid protein
Source: Venezuelan equine encephalitis virus. Organism_taxid: 11036. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (157 residues) CATH domains: 2.40.10.10 2.40.10.10
1i9w
Crystal structure of the fusion glycoprotein e1 from semliki forest virus
Source: Semliki forest virus. Organism_taxid: 11033
Chain: A (369 residues)
1kxa
Sindbis virus capsid, (wild-type) residues 106-264, tetragonal crystal form
Source: Sindbis virus. Organism_taxid: 11034. Gene: sindbis virus capsid protein. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: t7 RNA polymerase
Chain: A (158 residues) CATH domains: 2.40.10.10 2.40.10.10
1kxb
Sindbis virus capsid (s215a mutant), tetragonal crystal form
Source: Sindbis virus. Organism_taxid: 11034. Gene: sindbis virus capsid protein. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: t7 RNA polymerase
Chain: A (158 residues) CATH domains: 2.40.10.10 2.40.10.10
1kxc
Sindbis virus capsid (n190k mutant), tetragonal crystal form
Source: Sindbis virus. Organism_taxid: 11034. Gene: sindbis virus capsid protein. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: t7 RNA polymerase
Chain: A (158 residues) CATH domains: 2.40.10.10 2.40.10.10
1kxd
Sindbis virus capsid (n222l mutant), tetragonal crystal form
Source: Sindbis virus. Organism_taxid: 11034. Gene: sindbis virus capsid protein. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: t7 RNA polymerase
Chain: A (158 residues) CATH domains: 2.40.10.10 2.40.10.10
1kxe
Sindbis virus capsid (y180s, e183g double mutant), tetragonal crystal form
Source: Sindbis virus. Organism_taxid: 11034. Gene: sindbis virus capsid protein. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: t7 RNA polymerase
Chain: A (157 residues) CATH domains: 2.40.10.10 2.40.10.10
1kxf
Sindbis virus capsid, (wild-type) residues 1-264, tetragonal crystal form (form ii)
Source: Sindbis virus. Organism_taxid: 11034. Organ: kidney. Expressed in: cricetinae. Expression_system_taxid: 10026
Chain: A (159 residues) CATH domains: 2.40.10.10 2.40.10.10
1ld4
Placement of the structural proteins in sindbis virus
Source: Sindbis virus. Organism_taxid: 11034. Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 11034
Chains: A, B, C, D, M, N, O, P (151 residues)
1rer
Crystal structure of the homotrimer of fusion glycoprotein e semliki forest virus.
Source: Semliki forest virus. Organism_taxid: 11033
Chains: A, B, C (391 residues) CATH domains: 2.60.98.10 Unassigned 2.60.40.350
1svp
Sindbis virus capsid protein
Source: Sindbis virus. Organism_taxid: 11034. Gene: sindbis virus capsid protein. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: t7 RNA polymerase
Chains: A, B (160 residues) CATH domains: 2.40.10.10 2.40.10.10
1vcp
Semliki forest virus capsid protein (crystal form i)
Source: Semliki forest virus. Organism_taxid: 11033. Organ: kidney. Expressed in: cricetinae gen. Sp.. Expression_system_taxid: 36483
Chains: A, B, C (149 residues) CATH domains: 2.40.10.10 2.40.10.10
1vcq
Semliki forest virus capsid protein (crystal form ii)
Source: Semliki forest virus. Organism_taxid: 11033. Organ: kidney. Expressed in: cricetinae gen. Sp.. Expression_system_taxid: 36483
Chains: A, B (149 residues) CATH domains: 2.40.10.10 2.40.10.10
1wyk
Sindbis virus capsid protein (114-264)
Source: Sindbis virus. Organism_taxid: 11034. Strain: sa-ar 86. Cell_line: bl21. Gene: potential. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D (152 residues) CATH domains: 2.40.10.10 2.40.10.10
1z8y
Mapping the e2 glycoprotein of alphaviruses
Source: Sindbis virus. Organism_taxid: 11034. Strain: te12. Cell: bhk. Cell: bhk
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T (290 residues)
2ala
Crystal structure of the semliki forest virus envelope prote its monomeric conformation.
Source: Semliki forest virus. Organism_taxid: 11033
Chain: A (384 residues) CATH domains: 2.60.98.10 Unassigned 2.60.40.350
2rsw
Nmr structure, localization and vesicle fusion of chikunguny fusion peptide
Source: Synthetic: yes. Chikungunya virus. Chikv. Organism_taxid: 371094
Chain: A (18 residues)
2snv
The refined structure of sindbis virus core protein in comparison with other chymotrypsin-like serine proteinase structures
Source: Sindbis virus. Organism_taxid: 11034
Chain: A (151 residues) CATH domains: 2.40.10.10 2.40.10.10
2snw
Sindbis virus capsid protein, type3 crystal form
Source: Sindbis virus. Organism_taxid: 11034. Strain: sa-ar 86. Cell_line: baby hamster kidney cells (bhk21). Organ: kidney
Chains: A, B (158 residues) CATH domains: 2.40.10.10 2.40.10.10
2v33
High resolution crystal structure of domain iii of e1 fusion glycoprotein of semliki forest virus
Source: Semliki forest virus. Sfv. Organism_taxid: 11033
Chains: A, B (91 residues) CATH domain: 2.60.40.350
2yew
Modeling barmah forest virus structural proteins
Source: Barmah forest virus. Organism_taxid: 11020. Expressed in: mesocricetus auratus. Expression_system_taxid: 10036. Expression_system_cell_line: bhk-21. Expression_system_cell_line: bhk-21
Chains: A, B, C, D, E, F, G, H, I, J, K, L (171 residues)
3j0c
Models of e1, e2 and cp of venezuelan equine encephalitis vi strain restrained by a near atomic resolution cryo-em map
Source: Venezuelan equine encephalitis virus. Veev. Organism_taxid: 11037. Strain: tc-83. Other_details: purified from infected baby hamster kidney ( cells. Cells
Chains: A, B, C, D, E, F, G, H, I, J, K, L (442 residues)
3j0f
Sindbis virion
Source: Sindbis virus. Sinv. Organism_taxid: 11034. Organism_taxid: 11034
Chains: A, B, C, D, E, F, G, H, I, J, K, L (159 residues)
3j0g
Homology model of e3 protein of venezuelan equine encephalit tc-83 strain fitted with a cryo-em map
Source: Venezuelan equine encephalitis virus. Veev. Organism_taxid: 11037. Strain: tc-83. Other_details: purified from infected baby hamster kidney ( cells
Chains: M, N, O, P (59 residues)
3j2w
Electron cryo-microscopy of chikungunya virus
Source: Chikungunya virus. Chikv. Organism_taxid: 371095. Strain: 37997. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek 293f. Expression_system_cell_line: hek 293f
Chains: M, N, O, P, E, Q, F, R, G, S, H, T, I, J, K, L (336 residues)
3muu
Crystal structure of the sindbis virus e2-e1 heterodimer at
Source: Sindbis virus. Sinv. Organism_taxid: 11034. Strain: toto64. Expressed in: drosophila. Expression_system_taxid: 7215.
Chains: A, B, C, D, E, F (623 residues) CATH domains: Unassigned Unassigned Unassigned 2.60.40.350
3muw
Pseudo-atomic structure of the e2-e1 protein shell in sindbi
Source: Sindbis virus. Sinv. Organism_taxid: 11034. Strain: toto64. Strain: toto64
Chains: A, U, D, X, E, Y, F, Z (380 residues)
3ve6
Crystal structure analysis of venezuelan equine encephalitis capsid protein nls and importin alpha
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: kpna2, rch1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Venezuelan equine encephalitis virus. Organism_taxid: 11036.
Chain: B (12 residues)
4agj
Crystal structure of the capsid protein (110-267) from aura virus in complex with dioxane
Source: Aura virus. Organism_taxid: 44158. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chain: A (152 residues) CATH domains: 2.40.10.10 2.40.10.10
4agk
Crystal structure of capsid protein (110-267) from aura viru
Source: Aura virus. Organism_taxid: 44158. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chain: A (152 residues) CATH domains: 2.40.10.10 2.40.10.10
4aus
Crystal structure of c-terminal truncated (110-265) aura vir capsid protease.
Source: Aura virus. Organism_taxid: 44158. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta.
Chains: A, B (154 residues) CATH domains: 2.40.10.10 2.40.10.10
4uon
Crystal structure of c-terminal truncated (110-265) aura virus capsid protease.
Source: Aura virus. Organism_taxid: 44158. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta plyss.
Chains: A, B (154 residues) CATH domains: 2.40.10.10 2.40.10.10