_EC 3.4.21.72 IgA-specific serine endopeptidase. 1 PDB entries  
EC 3.-.-.- Hydrolases. [21,051 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [6,852 PDB entries]
EC 3.4.21.- Serine endopeptidases. [2,536 PDB entries]
EC 3.4.21.72 IgA-specific serine endopeptidase. [1 PDB entries]    
3h09

Reaction: Cleavage of immunoglobulin A molecules at certain Pro-|-Xaa bonds in the hinge region. No small molecule substrates are known.
Other name(s): IgA protease. Immunoglobulin A1 protease.
Comments: Species variants differing slightly in specificity are secreted by Gram-negative bacteria Neisseria gonorrhoeae and Haemophilus influenzae. Some other bacterial endopeptidases with similar specificity are of metallotype (see Ec 3.4.24.13). Belongs to peptidase family S6.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.3.4.21.72

  PDB code Protein
3h09
The structure of haemophilus influenzae iga1 protease
Source: Haemophilus influenzae. Organism_taxid: 727. Strain: rd kw20. Other_details: mutation of residues 1007-1012 to incoporate tag to c-temerminus of genomic copy
Chains: A, B (961 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned