_EC 3.4.21.60 Scutelarin. 0 PDB entries  
EC 3.-.-.- Hydrolases. [17,508 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [5,631 PDB entries]
EC 3.4.21.- Serine endopeptidases. [2,051 PDB entries]
EC 3.4.21.60 Scutelarin. [-]    

Reaction: Selective cleavage of Arg-|-Thr and Arg-|-Ile in prothrombin to form thrombin and two inactive fragments.
Other name(s): Taipan activator.
Comments: From the venom of the Taipan snake (Oxyuranus scutellatus). Converts prothrombin to thrombin. Specificity is similar to that of Factor Xa (EC 3.4.21.6). However, unlike Factor Xa this enzyme can cleave its target in the absence of coagulation Factor Va. Activity is potentiated by phospholipid and Ca(2+) which binds via gamma-carboxyglutamic acid residues. Similar enzymes are known from the venom of other Australian elapid snakes, including Pseudonaja textilis textilis, Oxyuranus microlepidotus and Demansia nuchalis affinis.
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There are no PDB entries in enzyme class E.C.3.4.21.60