_EC 3.4.21.45 Complement factor I. 1 PDB entries  
EC 3.-.-.- Hydrolases. [20,761 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [6,830 PDB entries]
EC 3.4.21.- Serine endopeptidases. [2,530 PDB entries]
EC 3.4.21.45 Complement factor I. [1 PDB entries]    
2xrc

Reaction: Inactivates complement subcomponents C3b, iC3b and C4b by proteolytic cleavage.
Other name(s): C3b inactivator. C3b/C4b inactivator. Complement component C3b inactivator.
Comments: Cleavage of complement subcomponent C3b requires its binding to cofactor H or complement receptor CR1; cleavage of iC3b requires complement receptor CR1; cleavage of C4b requires C4b-binding protein. Belongs to peptidase family S1.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.3.4.21.45

  PDB code Protein
2xrc
Human complement factor i
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: serum
Chains: A, B, C, D (461 residues) CATH domains: Unassigned Unassigned 3.10.250.10