_EC 3.4.21.34 Plasma kallikrein. 4 PDB entries  
EC 3.-.-.- Hydrolases. [21,051 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [6,852 PDB entries]
EC 3.4.21.- Serine endopeptidases. [2,536 PDB entries]
EC 3.4.21.34 Plasma kallikrein. [4 PDB entries]    
2anw

Reaction: Cleaves selectively Arg-|-Xaa and Lys-|-Xaa bonds, including Lys-|-Arg and Arg-|-Ser bonds in (human) kininogen to release bradykinin.
Other name(s): Kininogenin. Serum kallikrein.
Comments: Formed from plasma prokallikrein (Fletcher factor) by factor XIIa. Activates coagulation factors Xii, vii and plasminogen. Selective for Arg > Lys in P1, in small molecule substrates. Belongs to peptidase family S1. Formerly Ec 3.4.4.21 and Ec 3.4.21.8.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 4 PDB entries in enzyme class E.C.3.4.21.34

  PDB code Protein
2anw
Expression, crystallization and three-dimensional structure of the catalytic domain of human plasma kallikrein: implications for structure-based design of protease inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: klkb1, klk3. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chain: A (238 residues) CATH domains: 2.40.10.10 2.40.10.10
2any
Expression, crystallization and the three-dimensional structure of the catalytic domain of human plasma kallikrein: implications for structure-based design of protease inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: klkb1, klk3. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chain: A (238 residues) CATH domains: 2.40.10.10 2.40.10.10
4ogx
Crystal structure of fab dx-2930 in complex with human plasm kallikrein at 2.4 angstrom resolution
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: klk3, klkb1, klkb1_human. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (236 residues) CATH domains: Unassigned 2.40.10.10
4ogy
Crystal structure of fab dx-2930 in complex with human plasm kallikrein at 2.1 angstrom resolution
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: klk3, klkb1, klkb1_human. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B (239 residues) CATH domains: Unassigned 2.40.10.10