_EC 3.4.19.12 Ubiquitinyl hydrolase 1. 306 PDB entries  
EC 3.-.-.- Hydrolases. [21,051 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [6,852 PDB entries]
EC 3.4.19.- Omega peptidases. [377 PDB entries]
EC 3.4.19.12 Ubiquitinyl hydrolase 1. [306 PDB entries]    
1cmx

Reaction: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Other name(s): Ubiquitin C-terminal hydrolase. Ubiquitin carboxyl-terminal hydrolase. Ubiquitin thiolesterase.
Comments: Links to polypeptides smaller than 60 residues are hydrolyzed more readily than those to larger polypeptides. Isoforms exist with quantitatively different specificities among the best known being UCH-L1 and UCH-L3, major proteins of the brain of mammals. Inhibited by ubiquitin aldehyde (in which Gly76 is replaced by aminoacetaldehyde). Belongs to peptidase family C12.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 306 PDB entries in enzyme class E.C.3.4.19.12

  PDB code Protein
1cmx
Structural basis for the specificity of ubiquitin c- terminal hydrolases
Source: Synthetic: yes. Other_details: the protein was chemically synthesized. The sequence of this protein is naturally found in the cytoplasm of plasmid p-1a2/trpyuh1-1 of saccharomyces cerevisiae (baker's yeast). The expression system was escherichia coli, strain mm294, plasmid p-1a2/trpyuh1-1.. Escherichia coli, strain mm294, plasmid p-1a2/trpyuh1-1.
Chains: A, C (214 residues) CATH domain: 3.40.532.10
1ixd
Solution structure of the cap-gly domain from human cylindromatosis tomour-suppressor cyld
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fh04363. Other_details: cell-free protein synthesis
Chain: A (104 residues) CATH domain: 2.30.30.190
1lvo
Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha- helical domain
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1mbm
Nsp4 proteinase from equine arteritis virus
Source: Equine arteritis virus. Organism_taxid: 11047. Gene: nsp4. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (198 residues) CATH domains: 2.40.10.10 2.40.10.10 3.30.40.20
1nb8
Structure of the catalytic domain of usp7 (hausp)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (332 residues) CATH domains: Unassigned 2.20.210.10
1nbf
Crystal structure of a ubp-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: uba52. Expression_system_taxid: 562
Chains: A, B, E (347 residues) CATH domains: Unassigned 2.20.210.10
1p9s
Coronavirus main proteinase (3clpro) structure: basis for de anti-sars drugs
Source: Human coronavirus. Organism_taxid: 11137. Strain: 229e. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1p9u
Coronavirus main proteinase (3clpro) structure: basis for de anti-sars drugs
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: substrate-analog
Chains: A, B, C, D, E, F (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1q2w
X-ray crystal structure of the sars coronavirus main protease
Source: Sars coronavirus. Organism_taxid: 227859. Strain: urbani. Gene: orf1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (295 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1qz8
Crystal structure of sars coronavirus nsp9
Source: Sars coronavirus. Organism_taxid: 227859. Strain: frankfurt 1. Gene: nsp9. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (111 residues) CATH domain: 2.40.10.250
1tff
Structure of otubain-2
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, otb2, otu2, c14orf137. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (221 residues) CATH domains: Unassigned Unassigned
1uch
Deubiquitinating enzyme uch-l3 (human) at 1.8 angstrom resolution
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: b834 (de3). Tissue: hematopoetic. Cellular_location: cytoplasm. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: gal-met- auxotroph.
Chain: A (206 residues) CATH domain: 3.40.532.10
1uj1
Crystal structure of sars coronavirus main proteinase (3clpro)
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1uk2
Crystal structure of sars coronavirus main proteinase (3clpro) at ph8.0
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (302 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1uk3
Crystal structure of sars coronavirus main proteinase (3clpro) at ph7.6
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1uk4
Crystal structure of sars coronavirus main proteinase (3clpro) complexed with an inhibitor
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the sequence occurs peptide synthesis
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1uw7
Nsp9 protein from sars-coronavirus.
Source: Sars coronavirus hku-39849. Organism_taxid: 228404. Cell_line: vero e6. Expressed in: e. Coli.
Chain: A (122 residues) CATH domain: 2.40.10.250
1vdl
Solution structure of rsgi ruh-013, a uba domain in mouse cdna
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: riken cdna 2610101o11. Other_details: cell-free protein synthesis (e.Coli)
Chain: A (80 residues) CATH domain: 1.10.8.10
1vek
Solution structure of rsgi ruh-011, a uba domain from arabidopsis cdna
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: arabidopsis thaliana genomic DNA, chromosome 3, tac clone: k10d20. Other_details: cell-free protein synthesis system
Chain: A (84 residues) CATH domain: 1.10.8.10
1vjv
Crystal structure of ubiquitin carboxyl-terminal hydrolase 6 from saccharomyces cerevisiae at 1.74 a resolution
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ubp6, yfr010w. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (367 residues) CATH domain: 3.90.70.10
1w6v
Solution structure of the dusp domain of husp15
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Other_details: self made cdna library of multiple human carcinoma cell lines
Chain: A (120 residues) CATH domain: 3.30.2230.10
1wgg
Solution structure of the n-terminal ubiquitin-like domain of mouse ubiquitin specific protease 14 (usp14)
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: rekin cdna 2610005k12. Other_details: cell-free protein synthesis
Chain: A (96 residues) CATH domain: 3.10.20.90
1wh0
Solution structure of the cs domain of human usp19
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna hk08201. Other_details: cell-free protein synthesis
Chain: A (134 residues) CATH domain: 2.60.40.790
1whb
Solution structure of the rhodanese-like domain in human ubiquitin specific protease 8 (ubp8)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna ha01049. Other_details: cell-free protein synthesis
Chain: A (157 residues) CATH domain: 3.40.250.10
1whl
Solution structure of the 1st cap-gly domain in human cylindromatosis tumor suppressor cyld
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna fh04363. Other_details: cell-free protein synthesis
Chain: A (95 residues) CATH domain: 2.30.30.190
1whm
Solution structure of the 2nd cap-gly domain in human cylindromatosis tumor suppressor cyld
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kazusa cdna fh04363. Other_details: cell-free protein synthesis
Chain: A (92 residues) CATH domain: 2.30.30.190
1wiv
Solution structure of rsgi ruh-023, a uba domain from arabidopsis cdna
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: k10d20. Other_details: cell-free protein synthesis system
Chain: A (73 residues) CATH domain: 1.10.8.10
1wof
Crystal structure of sars-cov mpro in complex with an inhibitor n1
Source: Sars coronavirus. Organism_taxid: 227859. Strain: bj01. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (309 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1xd3
Crystal structure of uchl3-ubvme complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, C (229 residues) CATH domain: 3.40.532.10
1ysy
Nmr structure of the nonstructural protein 7 (nsp7) from the sars coronavirus
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (85 residues) CATH domain: Unassigned
1yy6
The crystal strucure of the n-terminal domain of hausp/usp7 complexed with an ebna1 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: the sequence of the peptide can be found naturally in epstein-barr virus
Chain: A (137 residues) CATH domain: 2.60.210.10
1yzb
Solution structure of the josephin domain of ataxin-3
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (182 residues) CATH domains: Unassigned 1.10.287.10
1yze
Crystal structure of the n-terminal domain of usp7/hausp.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C (101 residues)
1z1i
Crystal structure of native sars clpro
Source: Sars coronavirus. Organism_taxid: 227859
Chain: A (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
1z1j
Crystal structure of sars 3clpro c145a mutant
Source: Sars coronavirus. Organism_taxid: 227859
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2a5a
Crystal structure of unbound sars coronavirus main peptidase in the space group c2
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2a5i
Crystal structures of sars coronavirus main peptidase inhibi aza-peptide epoxide in the space group c2
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2a5k
Crystal structures of sars coronavirus main peptidase inhibited by an aza-peptide epoxide in space group p212121
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (304 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2a9u
Structure of the n-terminal domain of human ubiquitin carboxyl-terminal hydrolase 8 (usp8)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp8, kiaa0055, ubpy. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (134 residues)
2acf
Nmr structure of sars-cov non-structural protein nsp3a (sars sars coronavirus
Source: Sars coronavirus tor2. Organism_taxid: 227984. Strain: tor-2. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (172 residues) CATH domain: 3.40.220.10
2aga
De-ubiquitinating function of ataxin-3: insights from the solution structure of the josephin domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atxn3, atx3, mjd, mjd1, sca3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (190 residues) CATH domains: Unassigned 1.10.287.10
2ahm
Crystal structure of sars-cov super complex of non-structura proteins: the hexadecamer
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (77 residues) CATH domain: Unassigned
2alv
X-ray structural analysis of sars coronavirus 3cl proteinase in complex with designed anti-viral inhibitors
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (302 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2amd
Crystal structure of sars_cov mpro in complex with an inhibitor n9
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (309 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2amp
Crystal structure of porcine transmissible gastroenteritis virus mpro in complex with an inhibitor n1
Source: Transmissible gastroenteritis virus. Organism_taxid: 11149. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2amq
Crystal structure of sars_cov mpro in complex with an inhibitor n3
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (303 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2ayn
Structure of usp14, a proteasome-associated deubiquitinating enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C (337 residues) CATH domain: 3.90.70.10
2ayo
Structure of usp14 bound to ubquitin aldehyde
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp14, tgt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (355 residues) CATH domain: 3.90.70.10
2bx3
Crystal structure of sars coronavirus main proteinase (p43212)
Source: Sars coronavirus sin2774. Organism_taxid: 235410. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2bx4
Crystal structure of sars coronavirus main proteinase (p21212)
Source: Sars coronavirus sin2774. Organism_taxid: 235410. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (298 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2c3s
Structure of sars cov main proteinase at 1.9 a (ph6.5)
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sin2774. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (302 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2d2d
Crystal structure of sars-cov mpro in complex with an inhibitor i2
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2dag
Solution structure of the first uba domain in the human ubiquitin specific protease 5 (isopeptidase 5)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
Chain: A (74 residues) CATH domain: 1.10.8.10
2dak
Solution structure of the second uba domain in the human ubiquitin specific protease 5 (isopeptidase 5)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5. Expressed in: cell free synthesis. Other_details: cell-free protein synthesis
Chain: A (63 residues) CATH domain: Unassigned
2dos
Structural basis for the recognition of lys48-linked polyubiquitin chain by the josephin domain of ataxin-3, a putative deubiquitinating enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (171 residues) CATH domains: Unassigned 1.10.287.10
2duc
Crystal structure of sars coronavirus main proteinase(3clpro)
Source: Sars coronavirus. Organism_taxid: 227859. Other_details: cell-free protein synthesis
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2eqe
Solution structure of the fourth a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3. Other_details: cell-free protein synthesis
Chain: A (48 residues) CATH domain: Unassigned
2eqf
Solution structure of the 7th a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3. Other_details: cell-free protein synthesis
Chain: A (46 residues) CATH domain: Unassigned
2eqg
Solution structure of the first a20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3. Other_details: cell-free protein synthesis
Chain: A (49 residues) CATH domain: Unassigned
2etl
Crystal structure of ubiquitin carboxy-terminal hydrolase l1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (223 residues) CATH domain: 3.40.532.10
2f1w
Crystal structure of the traf-like domain of hausp/usp7
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (144 residues)
2f1x
Crystal structure of the traf-like domain of hausp/usp7 bound to a p53 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (137 residues)
2f1y
Crystal structure of the traf-like domain of hausp/usp7 bound to a mdm2 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (136 residues)
2f1z
Crystal structure of hausp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (470 residues) CATH domains: Unassigned Unassigned 2.20.210.10
2fav
Crystal structure of sars macro domain in complex with adp- ribose at 1.8 a resolution
Source: Sars coronavirus. Organism_taxid: 227859. Strain: frankfurt 1. Gene: nsp3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (172 residues) CATH domain: 3.40.220.10
2fe8
Sars coronavirus papain-like protease: structure of a viral deubiquitinating enzyme
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, C (315 residues) CATH domains: Unassigned Unassigned Unassigned
2foj
The crystal strucure of the n-terminal domain of hausp/usp7 complexed with p53 peptide 364-367
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
Chain: A (137 residues)
2foo
The crystal strucure of the n-terminal domain of hausp/usp7 complexed with p53 peptide 359-362
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
Chain: A (137 residues)
2fop
The crystal strucure of the n-terminal domain of hausp/usp7 complexed with mdm2 peptide 147-150
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
Chain: A (137 residues)
2fyg
Crystal structure of nsp10 from sars coronavirus
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor-2. Gene: orf1ab. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (128 residues) CATH domain: Unassigned
2g43
Structure of the znf ubp domain from deubiquitinating enzyme isopeptidase t (isot)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (117 residues) CATH domain: 3.30.40.10
2g45
Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase t (isot) in complex with ubiquitin
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp5, isot. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, D (117 residues) CATH domain: Unassigned
2g9t
Crystal structure of the sars coronavirus nsp10 at 2.1a
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X (118 residues) CATH domain: Unassigned
2ga6
The crystal structure of sars nsp10 without zinc ion as additive
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X (118 residues) CATH domain: Unassigned
2gdt
Nmr structure of the nonstructural protein 1 (nsp1) from the sars coronavirus
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (116 residues) CATH domain: Unassigned
2gfo
Structure of the catalytic domain of human ubiquitin carboxy hydrolase 8
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp8, kiaa0055, ubpy. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (339 residues) CATH domain: 3.90.70.10
2gri
Nmr structure of the sars-cov non-structural protein nsp3a
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (112 residues) CATH domain: Unassigned
2gt7
Crystal structure of sars coronavirus main peptidase at ph 6 space group p21
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2gt8
Crystal structure of sars coronavirus main peptidase (with a additional ala at the n-terminus of each protomer) in the s p43212
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (298 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2gtb
Crystal structure of sars coronavirus main peptidase (with a additional ala at the n-terminus of each protomer) inhibite aza-peptide epoxide in the space group p43212
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2gwf
Structure of a usp8-nrdp1 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp8, kiaa0055, ubpy. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Gene: rnf41.
Chains: A, C, E (136 residues) CATH domain: 3.40.250.10
2gx4
Crystal structure of sars coronavirus 3cl protease inhibitor
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2gz7
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of sars-cov main protease
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2gz8
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of sars-cov main protease
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2gz9
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of sars-cov main protease
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2h2z
Crystal structure of sars-cov main protease with authentic n and c-termini
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2h85
Crystal structure of nsp 15 from sars
Source: Sars coronavirus. Organism_taxid: 227859. Strain: frankfurt-1. Gene: nsp15. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (347 residues) CATH domains: Unassigned Unassigned Unassigned
2hd5
Usp2 in complex with ubiquitin
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp2, ubp41. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Cattle. Organism_taxid: 9913
Chain: A (315 residues) CATH domain: 3.90.70.10
2hob
Crystal structure of sars-cov main protease with authentic n and c-termini in complex with a michael acceptor n3
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2hsx
Nmr structure of the nonstructural protein 1 (nsp1) from the sars coronavirus
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (116 residues) CATH domain: Unassigned
2i50
Solution structure of ubp-m znf-ubp domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp16. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (122 residues) CATH domain: Unassigned
2ibi
Covalent ubiquitin-usp2 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp2, ubp41. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: rps27a, uba52, ubb, ubc.
Chain: A (335 residues) CATH domain: 3.90.70.10
2idy
Nmr structure of the sars-cov non-structural protein nsp3a
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (112 residues) CATH domain: Unassigned
2j97
Human coronavirus 229e non structural protein 9 (nsp9)
Source: Human coronavirus 229e. Hcov 229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (98 residues) CATH domain: 2.40.10.250
2j98
Human coronavirus 229e non structural protein 9 cys69ala mutant (nsp9)
Source: Human coronavirus 229e. Hcov 229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B (106 residues) CATH domain: 2.40.10.250
2jri
Solution structure of the josephin domain of ataxin-3 in complex with ubiquitin molecule.
Source: Homo sapiens. Human. Gene: atxn3, atx3, mjd, mjd1, sca3. Expressed in: escherichia coli. Expression_system_variant: de3. Gene: ubc.
Chain: A (182 residues) CATH domains: Unassigned 1.10.287.10
2jzd
Nmr structure of the domain 527-651 of the sars-cov nonstructural protein nsp3
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (129 residues) CATH domain: Unassigned
2jze
Nmr structure of the domain 527-651 of the sars-cov nonstructural protein nsp3, single conformer closest to the mean coordinates of an ensemble of twenty energy minimized conformers
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (129 residues) CATH domain: Unassigned
2jzf
Nmr conformer closest to the mean coordinates of the domain the sars-cov nonstructural protein nsp3
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (143 residues)
2k87
Nmr structure of a putative RNA binding protein (sars1) from coronavirus
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (116 residues)
2kaf
Solution structure of the sars-unique domain-c from the nons protein 3 (nsp3) of the severe acute respiratory syndrome c
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (67 residues) CATH domain: Unassigned
2klz
Solution structure of the tandem uim domain of ataxin-3 comp ubiquitin
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (46 residues) CATH domain: Unassigned
2kqv
Sars coronavirus-unique domain (sud): three-domain molecular architecture in solution and RNA binding. I: structure of t domain of sud-mc
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor2. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (129 residues)
2kqw
Sars coronavirus-unique domain (sud): three-domain molecular architecture in solution and RNA binding. Ii: structure of domain of sud-mc
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor2. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (67 residues)
2kvr
Solution nmr structure of human ubiquitin specific protease domain (residues 537-664). Nesg target hr4395c/ sgc-toronto
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (128 residues) CATH domain: Unassigned
2kys
Nmr structure of the sars coronavirus nonstructural protein solution at ph 6.5
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor2. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (85 residues) CATH domain: Unassigned
2kzr
Solution nmr structure of ubiquitin thioesterase otu1 (ec 3. From mus musculus, northeast structural genomics consortium mmt2a
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: yod1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (86 residues) CATH domain: 3.10.20.90
2l2d
Solution nmr structure of human uba-like domain of otud7a_11 target ht6304a/ocsp target otud7a_11_83/sgc-toronto
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otud7a, c15orf16, cezanne2, otud7. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (73 residues) CATH domain: 1.10.8.10
2l80
Solution structure of the zinc finger domain of usp13
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp13. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (114 residues) CATH domain: Unassigned
2l8k
Nmr structure of the arterivirus nonstructural protein 7 alp alpha)
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: bucyrus. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (123 residues) CATH domain: Unassigned
2lbc
Solution structure of tandem uba of usp13
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp13, isot3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (126 residues) CATH domains: 1.10.8.10 1.10.8.10
2len
Solution structure of uchl1 s18y variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (231 residues) CATH domain: 3.40.532.10
2liz
Nmr solution structure of c-terminal domain of sars-cov main in 2.5m urea
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (120 residues) CATH domain: 1.10.1840.10
2lva
Nmr solution structure of the n-terminal domain of human usp northeast structural genomics consortium target ht8470a
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp28, kiaa1515. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (111 residues) CATH domain: 1.10.8.10
2m0a
Solution structure of mhv nsp3a
Source: Murine hepatitis virus. Organism_taxid: 11142. Strain: a59. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (114 residues) CATH domain: Unassigned
2op9
Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the sars coronavirus
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor2. Gene: 3clpro. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (302 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2ozk
Structure of an n-terminal truncated form of nendou (nsp15) from sars-coronavirus
Source: Sars coronavirus. Organism_taxid: 227859. Strain: tor-2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (306 residues) CATH domains: Unassigned Unassigned Unassigned
2pwx
Crystal structure of g11a mutant of sars-cov 3c-like proteas
Source: Sars coronavirus. Organism_taxid: 228407. Strain: bj01. Gene: rep. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (289 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2q6g
Crystal structure of sars-cov main protease h41a mutant in c with an n-terminal substrate
Source: Sars coronavirus. Organism_taxid: 228407. Strain: bj01. Gene: rep. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes. Other_details: chemically synthesized.
Chains: A, B (305 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2qc2
Crystal structure of severe acute respiratory syndrome (sars protease asn214ala mutant
Source: Sars coronavirus. Virus. Gene: rep. Expressed in: escherichia coli.
Chains: A, B (305 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2qcy
Crystal structure of a monomeric form of severe acute respiratory syndrome (sars) 3c-like protease mutant
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2qiq
Structure-based design and synthesis and biological evaluation of peptidomimetic sars-3clpro inhibitors
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2qiy
Yeast deubiquitinase ubp3 and bre5 cofactor complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: bre5. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: ubp3.
Chains: C, D (25 residues)
2rhb
Crystal structure of nsp15-h234a mutant- hexamer in asymmetric unit
Source: Sars coronavirus. Organism_taxid: 227859. Strain: urbani isolate of sars-cov. Gene: nsp15. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell_line: bl21 star.
Chains: A, B, C, D, E, F (345 residues) CATH domains: Unassigned Unassigned Unassigned
2rnk
Nmr structure of the domain 513-651 of the sars-cov nonstructural protein nsp3
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (143 residues) CATH domain: Unassigned
2uzg
Zf-ubp domain of vdu1
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (95 residues) CATH domain: 3.30.40.10
2v6n
Crystal structures of the sars-coronavirus main proteinase inactivated by benzotriazole compounds
Source: Human sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2vfj
Structure of the a20 ovarian tumour (otu) domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (330 residues) CATH domain: Unassigned
2vhf
Structure of the cyld usp domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Chains: A, B (341 residues) CATH domain: Unassigned
2vri
Structure of the nsp3 x-domain of human coronavirus nl63
Source: Human coronavirus nl63. Hcov-nl63. Organism_taxid: 277944. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (173 residues) CATH domain: 3.40.220.10
2w2g
Human sars coronavirus unique domain
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (257 residues) CATH domains: Unassigned Unassigned
2wct
Human sars coronavirus unique domain (triclinic form)
Source: Sars coronavirus. Organism_taxid: 227859. Strain: sars-cov. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (257 residues) CATH domains: Unassigned Unassigned
2xxn
Structure of the virf4-hausp traf domain complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Human herpesvirus 8. Organism_taxid: 37296. Expression_system_taxid: 562
Chain: A (143 residues) CATH domain: Unassigned
2xyq
Crystal structure of the nsp16 nsp10 sars coronavirus comple
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (287 residues) CATH domain: Unassigned
2xyr
Crystal structure of the nsp16 nsp10 sars coronavirus comple
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (286 residues) CATH domain: Unassigned
2xyv
Crystal structure of the nsp16 nsp10 sars coronavirus comple
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (285 residues) CATH domain: Unassigned
2y5b
Structure of usp21 in complex with linear diubiquitin-aldehy
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, E (315 residues) CATH domain: 3.90.70.10
2y6e
Ubiquitin specific protease 4 is inhibited by its ubiquitin- like domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (337 residues) CATH domain: 3.90.70.10
2ylm
Mechanism of usp7 (hausp) activation by its c-terminal ubiquitin-like domain (hubl) and allosteric regulation by gmp-synthetase.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (529 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned
2yna
Crystal structure of the main protease of coronavirus hku4
Source: Tylonycteris bat coronavirus hku4. Organism_taxid: 694007. Strain: hku4-1l. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2ynb
Crystal structure of the main protease of coronavirus hku4 in complex with a michael acceptor sg85
Source: Tylonycteris bat coronavirus hku4. Organism_taxid: 694007. Strain: hku4-1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2yy4
Crystal structure of ms8104
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: cell-free protein synthesis.
Chains: A, B (310 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z3c
A mechanistic view of enzyme inhibition and peptide hydrolys active site of the sars-cov 3c-like peptidase
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z3d
A mechanistic view of enzyme inhibition and peptide hydrolys active site of the sars-cov 3c-like peptidase
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z3e
A mechanistic view of enzyme inhibition and peptide hydrolys active site of the sars-cov 3c-like peptidase
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z94
Complex structure of sars-cov 3c-like protease with tdt
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z9g
Complex structure of sars-cov 3c-like protease with pma
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z9j
Complex structure of sars-cov 3c-like protease with epdtc
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (302 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z9k
Complex structure of sars-cov 3c-like protease with jmf1600
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (305 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2z9l
Complex structure of sars-cov 3c-like protease with jmf1586
Source: Sars coronavirus. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2zfy
Crystal structure of human otubain 1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub1, otb1, otu1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (226 residues) CATH domains: Unassigned Unassigned
2zu2
Complex structure of cov 229e 3cl protease with epdtc
Source: Human coronavirus. Hcov-229e. Organism_taxid: 11137. Strain: 229e. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2zu4
Complex structure of sars-cov 3cl protease with tg-0204998
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
2zu5
Complex structure of sars-cov 3cl protease with tg-0205486
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3a7s
Catalytic domain of uch37
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uch37. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (204 residues) CATH domain: 3.40.532.10
3atw
Structure-based design, synthesis, evaluation of peptide-mim 3cl protease inhibitors
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was designed and chemically synt
Chains: A, B (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3avz
Structure of sars 3cl protease with peptidic aldehyde inhibi containing cyclohexyl side chain
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
Chain: A (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3aw0
Structure of sars 3cl protease with peptidic aldehyde inhibi
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3aw1
Structure of sars 3cl protease auto-proteolysis resistant mu the absent of inhibitor
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3by4
Structure of ovarian tumor (otu) domain in complex with ubiquitin
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: otu1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
Chain: A (172 residues) CATH domain: Unassigned
3c0r
Structure of ovarian tumor (otu) domain in complex with ubiq
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: otu1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Homo sapiens. Human. Organism_taxid: 9606.
Chains: A, C (175 residues) CATH domain: Unassigned
3d62
Development of broad-spectrum halomethyl ketone inhibitors a coronavirus main protease 3clpro
Source: Sars coronavirus. Organism_taxid: 227859. Gene: rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3dkb
Crystal structure of a20, 2.5 angstrom
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tnfaip3. Expressed in: escherichia coli.
Chains: A, B, C, D, E, F (352 residues) CATH domain: Unassigned
3e91
Crystal structure of sars-cov mpro mutant in p21 at ph6.9
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (305 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3e9s
A new class of papain-like protease/deubiquitinase inhibitors blocks sars virus replication
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (317 residues) CATH domains: Unassigned Unassigned Unassigned
3ea7
Crystal structure of sars-cov main protease triple mutant sti/a in space group p21
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (305 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3ea8
Crystal structure of sars-cov main protease triple mutant sti/a in space group c2
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3ea9
Crystal structure of sars-cov main protease quadruple mutant stif/a with one molecule in one asymmetric unit
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3eaj
Crystal structure of sars-cov main protease quadruple mutant stif/a with two molecules in one asymmetric unit
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (302 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3ebn
A special dimerization of sars-cov main proteasE C-terminal domain due to domain-swapping
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (100 residues) CATH domain: 1.10.1840.10
3ee7
Crystal structure of sars-cov nsp9 g104e
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: urbani. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (106 residues) CATH domain: 2.40.10.250
3ejg
Crystal structure of hcov-229e x-domain
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (165 residues) CATH domain: 3.40.220.10
3eti
Structure of a cubic crystal form of x (adrp) domain from fcov
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H (168 residues) CATH domain: 3.40.220.10
3ew5
Structure of the tetragonal crystal form of x (adrp) domain from fcov
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C (168 residues) CATH domain: 3.40.220.10
3ewq
Hcov-229e nsp3 adrp domain
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (167 residues) CATH domain: 3.40.220.10
3ewr
Complex of substrate adp-ribose with hcov-229e nsp3 adrp domain
Source: Human coronavirus 229e. Hcov-229e. Organism_taxid: 11137. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (167 residues) CATH domain: 3.40.220.10
3f9e
Crystal structure of the s139a mutant of sars-coronovirus 3c-like protease
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: bj01. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (297 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3f9f
Crystal structure of the f140a mutant of sars-coronovirus 3c-like protease at ph 6.0
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: bj01. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3f9g
Crystal structure of the f140a mutant of sars-coronovirus 3c-like protease at ph 6.5
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: bj01. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (297 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3f9h
Crystal structure of the f140a mutant of sars-coronovirus 3c-like protease at ph 7.6
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: bj01. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (299 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3fzd
Mutation of asn28 disrupts the enzymatic activity and dimeri sars 3clpro
Source: Sars coronavirus. Virus. Organism_taxid: 227859. Strain: tor2. Gene: 1a, sars 3cl protease. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (296 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3gzf
Structure of thE C-terminal domain of nsp4 from feline coron
Source: Feline coronavirus. Organism_taxid: 12663. Strain: fipv wsu-79. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E (96 residues)
3i3t
Crystal structure of covalent ubiquitin-usp21 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pp1490, usp21, usp23. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubq.
Chains: A, C, E, G (303 residues) CATH domain: 3.90.70.10
3ifw
Crystal structure of the s18y variant of ubiquitin carboxy t hydrolase l1 bound to ubiquitin vinylmethylester.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pgp9.5, uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubiq_
Chain: A (223 residues) CATH domain: 3.40.532.10
3ihp
Covalent ubiquitin-usp5 complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: isot, usp5. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2.
Chains: A, B (673 residues) CATH domains: Unassigned Unassigned 3.90.70.10 1.10.8.10 1.10.8.10
3ihr
Crystal structure of uch37
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ad-019, cgi-70, uch37, uchl5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (282 residues) CATH domain: 3.40.532.10
3irt
Crystal structure of the i93m mutant of ubiquitin carboxy-te hydrolase l1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pgp9.5, uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (223 residues) CATH domain: 3.40.532.10
3iwm
The octameric sars-cov main protease
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3j47
Formation of an intricate helical bundle dictates the assemb 26s proteasome lid
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Strain: atcc 204508 / s288c
Chain: V (63 residues)
3jyu
Crystal structure of the n-terminal domains of the ubiquitin specific peptidase 4 (usp4)
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: usp4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (220 residues) CATH domain: 3.30.2230.10
3jzt
Structure of a cubic crystal form of x (adrp) domain from fcov with adp-ribose
Source: Feline coronavirus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (168 residues) CATH domain: 3.40.220.10
3kvf
Crystal structure of the i93m mutant of ubiquitin carboxy te hydrolase l1 bound to ubiquitin vinylmethylester
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pgp9.5, uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubiq_
Chain: A (223 residues) CATH domain: 3.40.532.10
3kw5
Crystal structure of ubiquitin carboxy terminal hydrolase l1 ubiquitin vinylmethylester
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pgp9.5, uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubiq_
Chain: A (223 residues) CATH domain: 3.40.532.10
3lmn
Oligomeric structure of the dusp domain of human usp15
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0529, usp15. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (132 residues) CATH domain: 3.30.2230.10
3m3s
Crystal structure of sars-cov main protease asn214ala mutant authorize n-terminus
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: main protease. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3m3t
Sars-cov main protease monomeric arg298ala mutant with n-ter additional residues (gly-ser)
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (307 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3m3v
Sars-cov main protease triple mutant sti/a with two n-termin additional residue (gly-ser)
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3m99
Structure of the ubp8-sgf11-sgf73-sus1 saga dub module
Source: Saccharomyces cerevisiae. Brewer's yeast,lager beer yeast,yeast. Organism_taxid: 4932. Gene: ubp8, ym9959.05, ymr223w. Expressed in: escherichia coli. Expression_system_taxid: 562. Yeast. Gene: sgf11, ypl047w. Gene: sus1, ybr111w-a.
Chain: A (422 residues) CATH domains: Unassigned 3.90.70.10
3mhh
Structure of the saga ubp8/sgf11/sus1/sgf73 dub module
Source: Saccharomyces cerevisiae. Brewer's yeast,lager beer yeast,yeast. Organism_taxid: 4932. Gene: ubp8, ymr223w, ym9959.05. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w. Gene: sgf73, ygl066w.
Chain: A (433 residues) CATH domains: Unassigned 3.90.70.10
3mhs
Structure of the saga ubp8/sgf11/sus1/sgf73 dub module bound ubiquitin aldehyde
Source: Saccharomyces cerevisiae. Brewer's yeast,lager beer yeast,yeast. Organism_taxid: 4932. Gene: ubp8, ymr223w, ym9959.05. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w. Homo sapiens.
Chain: A (455 residues) CATH domains: Unassigned 3.90.70.10
3mj5
Severe acute respiratory syndrome-coronavirus papain-like pr inhibitors: design, synthesis, protein-ligand x-ray structu biological evaluation
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Strain: urbani. Gene: 1a, orf1 (nsp3) residues 1544-1855. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (312 residues) CATH domains: Unassigned Unassigned Unassigned
3mp2
Crystal structure of transmissible gastroenteritis virus pap protease 1
Source: Porcine transmissible gastroenteritis coronavirus. Tgev. Organism_taxid: 11151. Strain: purdue. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (211 residues) CATH domain: Unassigned
3mqr
Crystal structure of the usp7:hdmx(ahss) complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Strain: human. Gene: hausp, usp7. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
Chain: A (137 residues)
3mqs
Crystal structure of the usp7:hdm2(psts) complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
Chain: C (137 residues)
3mtn
Usp21 in complex with a ubiquitin-based, usp21-specific inhi
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pp1490, usp21, usp23. Expressed in: escherichia coli. Expression_system_taxid: 511693. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubq.
Chains: A, C (316 residues) CATH domain: 3.90.70.10
3n3k
The catalytic domain of usp8 in complex with a usp8 specific
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0055, ubpy, usp8. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: rps27a, uba52, uba80, ubb, ubc, ubcep1, ubcep2, ubq.
Chain: A (355 residues) CATH domain: 3.90.70.10
3nhe
High resolution structure (1.26a) of usp2a in complex with u
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubp41, usp2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: rps27a, uba52, ubb, ubc.
Chain: A (338 residues) CATH domain: 3.90.70.10
3o65
Crystal structure of a josephin-ubiquitin complex: evolution restraints on ataxin-3 deubiquitinating activity
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: atx3l, atxn3l, mjdl. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubb.
Chains: A, C, E, G (181 residues) CATH domains: Unassigned 1.10.287.10
3oj3
Crystal structure of the a20 znf4 and ubiquitin complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubb. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: tnfaip3, otud7c.
Chains: I, J, K, L, M, N, O, P (33 residues)
3oj4
Crystal structure of the a20 znf4, ubiquitin and ubch5a comp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d1, sft, ubc5a, ubch5, ubch5a. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubb. Gene: tnfaip3, otud7c.
Chains: C, F (31 residues)
3pfy
The catalytic domain of human otud5
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otud5. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (129 residues) CATH domains: Unassigned Unassigned
3phu
Otu domain of crimean congo hemorrhagic fever virus
Source: Crimean-congo hemorrhagic fever virus ibar10200. Cchfv. Organism_taxid: 652961. Strain: nigeria/ibar10200/1970. Gene: l. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (184 residues) CATH domains: Unassigned Unassigned
3phw
Otu domain of crimean congo hemorrhagic fever virus in compl ubiquitin
Source: Crimean-congo hemorrhagic fever virus ibar10200. Cchfv. Organism_taxid: 652961. Strain: nigeria/ibar10200/1970. Gene: l. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens.
Chains: A, C, E, G (156 residues) CATH domain: Unassigned
3phx
Otu domain of crimean congo hemorrhagic fever virus in compl isg15
Source: Crimean-congo hemorrhagic fever virus. Cchfv. Organism_taxid: 652961. Strain: nigeria/ibar10200/1970. Gene: l. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
Chain: A (162 residues) CATH domain: Unassigned
3ppa
Structure of the dusp-ubl domains of usp15
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0529, usp15. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (209 residues) CATH domain: 3.30.2230.10
3pv1
Crystal structure of the usp15 dusp-ubl domains
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp15, kiaa0529. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (215 residues) CATH domain: 3.30.2230.10
3r24
Crystal structure of nsp10/nsp16 complex of sars coronavirus possible
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: 1a.
Chains: A, B (292 residues) CATH domain: Unassigned
3rii
Crystal structure of the catalytic domain of uchl5, a protea associated human deubiquitinating enzyme, reveals an unprod form of the enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ad-019, cgi-70, uch37, uchl5. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (212 residues) CATH domain: 3.40.532.10
3ris
Crystal structure of the catalytic domain of uchl5, a protea associated human deubiquitinating enzyme, reveals an unprod form of the enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ad-019, cgi-70, uch37, uchl5. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (227 residues) CATH domain: 3.40.532.10
3sn8
Crystal structure of sars coronavirus main protease complexe ff-h (soaking)
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3sna
Crystal structure of sars coronavirus main protease complexe nsfsq-h (soaking)
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: A (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3snb
Crystal structure of sars coronavirus main protease complexe dsfdq-h (soaking)
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3snc
Crystal structure of sars coronavirus main protease complexe nstsq-h (soaking)
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3snd
Crystal structure of sars coronavirus main protease complexe estlq-h (cocrystallization)
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3sne
Crystal structure of sars coronavirus main protease complexe estlq-h (soaking)
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3sqa
Crystal structure of the uch domain of uch-l5 with 6 residue
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ad-019, cgi-70, uch-l5, uch37, uchl5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (204 residues) CATH domain: 3.40.532.10
3szn
Crystal structure of sars coronavirus main protease complexe alpha, beta-unsaturated ethyl ester sg75
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3t9l
Structure of n-terminal dusp-ubl domains of human usp15
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: kiaa0529, usp15, usp15 (1-222). Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (222 residues) CATH domain: 3.30.2230.10
3tb3
Crystal structure of the uch domain of uch-l5 with 6 residue
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ad-019, cgi-70, uch-l5, uch37, uchl5. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (204 residues) CATH domain: 3.40.532.10
3tit
Crystal structure of sars coronavirus main protease complexe alpha, beta-unsaturated ethyl ester sg81
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3tiu
Crystal structure of sars coronavirus main protease complexe alpha,beta-unsaturated ethyl ester inhibitor sg82
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3tlo
Crystal structure of hcov-nl63 3c-like protease
Source: Human coronavirus. Hcov-nl63. Organism_taxid: 277944. Strain: nl63. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (302 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3tmo
The catalytic domain of human deubiquitinase duba
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: duba, otud5. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (141 residues) CATH domains: Unassigned Unassigned
3tmp
The catalytic domain of human deubiquitinase duba in complex ubiquitin aldehyde
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: duba, otud5. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc, ubiquitin aldehyde. Expression_system_taxid: 562
Chains: A, C, E, G (166 residues) CATH domain: Unassigned
3tns
Crystal structure of sars coronavirus main protease complexe alpha, beta-unsaturated ethyl ester inhibitor sg83
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3tnt
Crystal structure of sars coronavirus main protease complexe alpha, beta-unsaturated ethyl ester inhibitor sg85
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3u12
The pleckstrin homology (ph) domain of usp37
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp37. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (104 residues) CATH domain: Unassigned
3ub0
Crystal structure of the nonstructural protein 7 and 8 compl feline coronavirus
Source: Feline infectious peritonitis virus. Fcov. Organism_taxid: 33734. Strain: fipv wsu-79/1146. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (190 residues) CATH domains: Unassigned Unassigned
3v3m
Severe acute respiratory syndrome coronavirus (sars-cov) 3cl in complex with n-[(1r)-2-(tert-butylamino)-2-oxo-1-(pyridi ethyl]-n-(4-tert-butylphenyl)furan-2-carboxamide inhibitor.
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: homo sapiens. Expression_system_taxid: 9606
Chain: A (306 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3v6c
Crystal structure of usp2 in complex with mutated ubiquitin
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubp41, usp02.258.605, usp2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc.
Chain: A (327 residues) CATH domain: 3.90.70.10
3v6e
Crystal structure of usp2 and a mutant form of ubiquitin
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubp41, usp02.258.605, usp2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc.
Chain: A (328 residues) CATH domain: 3.90.70.10
3vb3
Crystal structure of sars-cov 3c-like protease in apo form
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3vb4
Crystal structure of sars-cov 3c-like protease with b4z
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic inhibitor
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3vb5
Crystal structure of sars-cov 3c-like protease with c4z
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic inhibitor
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3vb6
Crystal structure of sars-cov 3c-like protease with c6z
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic inhibitor
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3vb7
Crystal structure of sars-cov 3c-like protease with m4z
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic inhibitor
Chains: A, B (301 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
3vc8
Crystal structure of thE C-terminal cytoplasmic domain of no structural protein 4 from mouse hepatitis virus a59
Source: Murine hepatitis virus. Organism_taxid: 591071. Strain: a59. Gene: murine hepatitis virus strain a59 orf1ab, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (81 residues) CATH domain: Unassigned
3vcb
C425s mutant of thE C-terminal cytoplasmic domain of non-str protein 4 from mouse hepatitis virus a59
Source: Murine hepatitis virus. Organism_taxid: 591071. Strain: a59. Gene: murine hepatitis virus strain a59 orf1ab, orf1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (89 residues) CATH domain: Unassigned
3von
Crystalstructure of the ubiquitin protease
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hspc263, otb1, otu1, otub1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: mms2, ube2v2, uev2. Gene: blu, ubc13, ube2n.
Chains: A, H, O, V, c, j (210 residues) CATH domains: Unassigned Unassigned
3vuw
Crystal structure of a20 zf7 in complex with linear ubiquiti
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: tnfaip3.
Chains: E, F, G (31 residues)
3vux
Crystal structure of a20 zf7 in complex with linear ubiquiti
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: tnfaip3.
Chains: E, F, G (33 residues)
3vuy
Crystal structure of a20 zf7 in complex with linear tetraubi
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: tnfaip3.
Chains: D, F, E (33 residues)
3zbd
Structure of tgev nsp1
Source: Porcine transmissible gastroenteritis coronavirus. Organism_taxid: 11151. Strain: purdue. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (110 residues) CATH domain: Unassigned
3zjd
A20 otu domain in reduced, active state at 1.87 a resolution
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (325 residues) CATH domain: Unassigned
3zje
A20 otu domain in reversibly oxidised (soh) state
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (329 residues) CATH domain: Unassigned
3zjf
A20 otu domain with irreversibly oxidised cys103 from 270 mi soak.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (323 residues) CATH domain: Unassigned
3zjg
A20 otu domain with irreversibly oxidised cys103 from 60 min h2o2 soak.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (327 residues) CATH domain: Unassigned
3znh
Crimean congo hemorrhagic fever virus otu domain in complex with ubiquitin-propargyl.
Source: Crimean-congo hemorrhagic fever virus. Organism_taxid: 652961. Strain: ibar10200. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta2 placi. Other_details: DNA generated by gene synthesis. Synthetic: yes. Homo sapiens.
Chain: A (153 residues) CATH domain: Unassigned
3znv
Crystal structure of the otu domain of otulin at 1.3 angstro
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta placi.
Chain: A (269 residues) CATH domain: Unassigned
3znx
Crystal structure of the otu domain of otulin d336a mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta placi.
Chain: A (260 residues) CATH domain: Unassigned
3znz
Crystal structure of otulin otu domain (c129a) in complex with met1-di ubiquitin
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: rosetta placi.
Chain: A (266 residues) CATH domain: Unassigned
3zrh
Crystal structure of the lys29, lys33-linkage-specific trabi deubiquitinase domain reveals an ankyrin-repeat ubiquitin b domain (ankubd)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Other_details: arcticexpress competent cells
Chain: A (428 residues) CATH domains: Unassigned Unassigned
4a3o
Crystal structure of the usp15 dusp-ubl monomer
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (211 residues) CATH domain: 3.30.2230.10
4a3p
Structure of usp15 dusp-ubl deletion mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (210 residues) CATH domain: 3.30.2230.10
4bop
Structure of otud1 otu domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi
Chains: A, B (149 residues) CATH domain: Unassigned
4boq
Structure of otud2 otu domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi
Chain: A (175 residues) CATH domain: Unassigned
4bos
Structure of otud2 otu domain in complex with ubiquitin k11- linked peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi.
Chains: A, B (164 residues) CATH domain: Unassigned
4bou
Structure of otud3 otu domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi.
Chain: A (141 residues) CATH domain: Unassigned
4boz
Structure of otud2 otu domain in complex with k11-linked di
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: rosetta placi.
Chains: A, D (158 residues) CATH domain: Unassigned
4cr2
Deep classification of a large cryo-em dataset defines the conformational landscape of the 26s proteasome
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 4932
Chain: V (247 residues)
4cr3
Deep classification of a large cryo-em dataset defines the conformational landscape of the 26s proteasome
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 4932
Chain: V (247 residues)
4cr4
Deep classification of a large cryo-em dataset defines the conformational landscape of the 26s proteasome
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 4932
Chain: V (247 residues)
4ddg
Crystal structure of human otub1/ubch5b~ub/ub
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: e2, hspc263, otb1, otu1, otub1, ubc4, ubc5b, ubch4, u ube2d2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
Chains: A, B, C, J, K, L (399 residues) CATH domain: 3.10.110.10
4ddi
Crystal structure of human otub1/ubch5b~ub/ub
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ube2d2, ubc4, ubc5b, ubch4, ubch5b, hspc263, otb1, ot otub1. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
Chains: A, B, C (399 residues) CATH domain: 3.10.110.10
4dhi
Structure of c. Elegans otub1 bound to human ubc13
Source: Caenorhabditis elegans. Nematode. Organism_taxid: 6239. Gene: otub-1, c25d7.8. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
Chain: B (238 residues) CATH domains: Unassigned Unassigned
4dhj
The structure of a ceotub1 ubiquitin aldehyde ubc13~ub compl
Source: Caenorhabditis elegans. Nematode. Organism_taxid: 6239. Gene: otub-1, c25d7.8. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
Chains: A, E, I, L (248 residues) CATH domains: Unassigned Unassigned
4dhz
The structure of h/ceotub1-ubiquitin aldehyde-ubc13~ub
Source: Homo sapiens, caenorhabditis elegans. Human, nematode. Organism_taxid: 9606, 6239. Gene: otub1, otb1, otu1, hspc263, c25d7.8, otub-1. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
Chain: A (256 residues) CATH domains: Unassigned Unassigned
4dm9
The crystal structure of ubiquitin carboxy-terminal hydrolas (uchl1) bound to a tripeptide fluoromethyl ketone z-vae(ome
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (223 residues) CATH domain: 3.40.532.10
4f49
2.25a resolution structure of transmissible gastroenteritis protease containing a covalently bound dipeptidyl inhibitor
Source: Porcine transmissible gastroenteritis coronavirus. Tgev. Organism_taxid: 11151. Strain: purdue. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C, D (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
4fip
Structure of the saga ubp8(s144n)/sgf11(1-72, delta-znf)/sus dub module
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubp8, ym9959.05, ymr223w. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w.
Chains: A, E (450 residues) CATH domains: Unassigned Unassigned
4fjc
Structure of the saga ubp8/sgf11(1-72, delta-znf)/sus1/sgf73 module
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubp8, ym9959.05, ymr223w. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w.
Chains: A, E (447 residues) CATH domains: Unassigned Unassigned
4fjv
Crystal structure of human otubain2 and ubiquitin complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub2, c14orf137, otb2, otu2. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
Chains: A, C (231 residues) CATH domains: Unassigned Unassigned
4fk5
Structure of the saga ubp8(s144n)/sgf11/sus1/sgf73 dub modul
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: ubp8, ym9959.05, ymr223w. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: sus1, ybr111w-a. Gene: sgf11, ypl047w.
Chain: A (437 residues) CATH domains: Unassigned Unassigned
4hi3
Crystal structure of dimeric r298a mutant of sars coronaviru protease
Source: Sars coronavirus. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (300 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
4hxd
Diversity of ubiquitin and isg15 specificity amongst nairovi viral ovarian tumor domain proteases
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 469008. Dugbe virus (isolate ard44313). Dugv. Organism_taxid: 766194.
Chains: B, D (157 residues) CATH domain: Unassigned
4i6l
Crystal structure of otub1 in complex with ubiquitin variant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: otub1, otb1, otu1, hspc263. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: ubc. Expression_system_taxid: 562
Chain: A (217 residues) CATH domains: Unassigned Unassigned
4ium
Equine arteritis virus papain-like protease 2 (plp2) covalen to ubiquitin
Source: Equine arteritis virus. Eav. Organism_taxid: 11047. Gene: rep, 1a-1b. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
Chain: A (127 residues) CATH domain: Unassigned
4jjq
Crystal structure of usp7-ntd with an e2 enzyme
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7, usp7/hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Other_details: synthesized peptide
Chain: A (137 residues) CATH domain: Unassigned
4jkj
Crystal structure of the s18y variant of ubiquitin carboxy-t hydrolase l1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: uchl1. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (223 residues) CATH domain: 3.40.532.10
4kg9
Crystal structure of usp7-ntd with mcm-bp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hausp, usp7. Expressed in: escherichia coli. Expression_system_taxid: 511693. Synthetic: yes. Organism_taxid: 9606
Chain: A (138 residues) CATH domain: Unassigned
4ksk
Gumby/fam105b in complex with ubiquitin
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fam105b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc.
Chains: A, B (260 residues) CATH domain: Unassigned
4ksl
Gumby/fam105b in complex with linear di-ubiquitin
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fam105b. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: ubc.
Chains: A, B, E, G, I, K, M, O, Q, S, U, W (263 residues) CATH domain: Unassigned
4ldt
The structure of h/ceotub1-ubiquitin aldehyde-ubch5b~ub
Source: Homo sapiens, caenorhabditis elegans. Human, nematode. Organism_taxid: 9606, 6239. Gene: otub1, otb1, otu1, hspc263, c25d7.8, otub-1. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
Chain: A (255 residues) CATH domains: Unassigned Unassigned
4m0w
Crystal structure of sars-cov papain-like protease c112s mut complex with ubiquitin
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a, nsp3. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Bovine. Organism_taxid: 9913.
Chain: A (317 residues) CATH domains: Unassigned Unassigned Unassigned
4m5w
Crystal structure of the usp7/hausp catalytic domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (343 residues) CATH domains: Unassigned 2.20.210.10
4m5x
Crystal structure of the usp7/hausp catalytic domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (339 residues) CATH domains: Unassigned 2.20.210.10
4mds
Discovery of n-(benzo[1,2,3]triazol-1-yl)-n-(benzyl)acetamid carboxamides as severe acute respiratory syndrome coronavir cov) 3clpro inhibitors: identification of ml300 and non-cov nanomolar inhibitors with an induced-fit binding
Source: Sars coronavirus. Sars-cov. Organism_taxid: 227859. Gene: 1a. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (303 residues) CATH domains: 2.40.10.10 2.40.10.10 1.10.1840.10
4mel
Crystal structure of the human usp11 dusp-ubl domains
Source: Homo sapiens. Human. Organism_taxid: 9606. Strain: 9606. Gene: uhx1, usp11. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (213 residues)
4mem
Crystal structure of the rat usp11 dusp-ubl domains
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Strain: 10116. Gene: rcg_42884, usp11. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (212 residues)
4mm3
Crystal structure of sars-cov papain-like protease plpro in with ubiquitin aldehyde
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ubc. Expressed in: escherichia coli. Expression_system_taxid: 562. Sars coronavirus. Sars-cov. Organism_taxid: 227859.
Chain: B (316 residues) CATH domains: Unassigned Unassigned Unassigned
4n0n
Crystal structure of arterivirus nonstructural protein 10 (h
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: equine arteritis virus. Gene: 1a-1b, nsp10, rep. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (401 residues)
4n0o
Complex structure of arterivirus nonstructural protein 10 (h with DNA
Source: Equine arteritis virus. Eav. Organism_taxid: 299386. Strain: equine arteritis virus. Gene: 1a-1b, nsp10, rep. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, C, E, G (395 residues)
4ovz
X-ray structural and biological evaluation of a series of po highly selective inhibitors of human coronavirus papain-lik proteases
Source: Sars coronavirus. Organism_taxid: 228330. Strain: urbani. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (305 residues) CATH domains: Unassigned Unassigned Unassigned
4ow0
X-ray structural and biological evaluation of a series of po highly selective inhibitors of human coronavirus papain-lik proteases
Source: Sars coronavirus. Organism_taxid: 228330. Strain: urbani. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (312 residues) CATH domains: Unassigned Unassigned Unassigned
4oyk
Structure of hoip pub domain bound to otulin pim
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnf31,zibra. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606
Chains: C, D (13 residues)
4pyz
Crystal structure of the first two ubl domains of deubiquity
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: usp7, hausp. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (263 residues)