_EC 3.4.15.4 Peptidyl-dipeptidase B. 0 PDB entries  
EC 3.-.-.- Hydrolases. [22,079 PDB entries]
EC 3.4.-.- Acting on peptide bonds (peptide hydrolases). [7,224 PDB entries]
EC 3.4.15.- Peptidyl-dipeptidases. [51 PDB entries]
EC 3.4.15.4 Peptidyl-dipeptidase B. [-]    

Reaction: Release of a C-terminal dipeptide or exceptionally a tripeptide.
Other name(s): Atrial di-(tri-)peptidyl carboxylase. Atriopeptin convertase. Dipeptidyl carboxyhydrolase.
Cofactor(s): Zn(2+).
Comments: A membrane-bound, zinc metallopeptidase located in mammalian atrial, but not ventricular, myocytes. Although it is capable of converting the 126-residue atriopeptin Iii directly to atriopeptin I by releasing a C-terminal tripeptide Phe- Arg-Tyr, it is generally restricted to the release of dipeptides. In contrast to Ec 3.4.15.1 it displays no chlorine dependence and shows no action on angiotensin I. Conversely, peptidyl-dipeptidase a is unable to release Phe-Arg from the C-terminus of atriopeptin Ii.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.3.4.15.4