_EC 3.2.1.49 Alpha-N-acetylgalactosaminidase. 11 PDB entries  
EC 3.-.-.- Hydrolases. [21,051 PDB entries]
EC 3.2.-.- Glycosylases. [4,101 PDB entries]
EC 3.2.1.- Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compound [3,577 PDB entries]
EC 3.2.1.49 Alpha-N-acetylgalactosaminidase. [11 PDB entries]    
1ktb

Reaction: Cleavage of non-reducing alpha-(1->3)-N-acetylgalactosamine residues from human blood group A and ab mucin glycoproteins, Forssman hapten and blood group A lacto series glycolipids.
Other name(s): Alpha-galactosidase B. Alpha-GalNAcase. Alpha-Naga.
Comments: The human lysosomal enzyme is involved in the degradation of blood type A epitope.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 11 PDB entries in enzyme class E.C.3.2.1.49

  PDB code Protein
1ktb
The structure of alpha-n-acetylgalactosaminidase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: alpha-naga. Expressed in: pichia pastoris. Expression_system_taxid: 4922.
Chain: A (388 residues) CATH domains: 3.20.20.70 2.60.40.1180
1ktc
The structure of alpha-n-acetylgalactosaminidase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: alpha-naga. Expressed in: pichia pastoris. Expression_system_taxid: 4922.
Chain: A (388 residues) CATH domains: 3.20.20.70 2.60.40.1180
2ixa
A-zyme, n-acetylgalactosaminidase
Source: Flavobacterium meningosepticum. Organism_taxid: 238. Atcc: 13253. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: plyss.
Chain: A (426 residues) CATH domains: 3.40.50.720 3.30.360.10
2ixb
Crystal structure of n-acetylgalactosaminidase in complex with galnac
Source: Flavobacterium meningosepticum. Organism_taxid: 238. Atcc: 13253. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: plyss.
Chain: A (426 residues) CATH domains: 3.40.50.720 3.30.360.10
3h53
Crystal structure of human alpha-n-acetylgalactosaminidase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: naga. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (387 residues) CATH domains: 3.20.20.70 2.60.40.1180
3h54
Crystal structure of human alpha-n-acetylgalactosaminidasE,C with galnac
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: naga. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (387 residues) CATH domains: 3.20.20.70 2.60.40.1180
3h55
Crystal structure of human alpha-n-acetylgalactosaminidase, with galactose
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: naga. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (387 residues) CATH domains: 3.20.20.70 2.60.40.1180
3igu
Crystal structure of human alpha-n-acetylgalactosaminidase, intermediate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: naga. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (387 residues) CATH domains: 3.20.20.70 2.60.40.1180
4do4
Pharmacological chaperones for human alpha-n-acetylgalactosa
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: naga. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (387 residues) CATH domains: 3.20.20.70 2.60.40.1180
4do5
Pharmacological chaperones for human alpha-n-acetylgalactosa
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: naga. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (387 residues) CATH domains: 3.20.20.70 2.60.40.1180
4do6
Pharmacological chaperones for human alpha-n-acetylgalactosa
Source: Homo sapiens. Organism_taxid: 9606. Gene: naga. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (388 residues) CATH domains: 3.20.20.70 2.60.40.1180