_EC 3.2.1.35 Hyaluronoglucosaminidase. 14 PDB entries  
EC 3.-.-.- Hydrolases. [21,057 PDB entries]
EC 3.2.-.- Glycosylases. [4,107 PDB entries]
EC 3.2.1.- Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compound [3,582 PDB entries]
EC 3.2.1.35 Hyaluronoglucosaminidase. [14 PDB entries]    
1fcq

Reaction: Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
Other name(s): Chondroitinase. Chondroitinase I. Hyaluronidase. Hyaluronoglucosidase.
Comments: Also hydrolyzes 1,4-beta-D-glycosidic linkages between N-acetyl- galactosamine or N-acetylgalactosamine sulfate and glucuronic acid in chondroitin, chondroitin 4- and 6-sulfates, and dermatan. Formerly Ec 3.2.1.34.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 14 PDB entries in enzyme class E.C.3.2.1.35

  PDB code Protein
1fcq
Crystal structure (monoclinic) of bee venom hyaluronidase
Source: Apis mellifera. Honey bee. Organism_taxid: 7460. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell: high-five insect cells.
Chain: A (314 residues) CATH domain: 3.20.20.70
1fcu
Crystal structure (trigonal) of bee venom hyaluronidase
Source: Apis mellifera. Honey bee. Organism_taxid: 7460. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell: high-five insect cells.
Chain: A (324 residues) CATH domain: 3.20.20.70
1fcv
Crystal structure of bee venom hyaluronidase in complex with hyaluronic acid tetramer
Source: Apis mellifera. Honey bee. Organism_taxid: 7460. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell: high-five insect cells.
Chain: A (324 residues) CATH domain: 3.20.20.70
2atm
Crystal structure of the recombinant allergen ves v 2
Source: Vespula vulgaris. Organism_taxid: 7454. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (324 residues) CATH domain: 3.20.20.70
2j88
Hyaluronidase in complex with a monoclonal igg fab fragment
Source: Apis mellifera. Honey bee. Organism_taxid: 7460. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_variant: high five. Mus musculus. House mouse. Organism_taxid: 10090.
Chain: A (319 residues) CATH domain: 3.20.20.70
2jnk
Solution sructure of a dockerin-containing modular pair from a family 84 glycoside hydrolase
Source: Clostridium perfringens. Organism_taxid: 1502. Gene: nagh. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (140 residues) CATH domain: 1.20.1270.90
2ls6
Solution nmr structure of a non-canonical galactose-binding clostridium perfringens
Source: Clostridium perfringens. Organism_taxid: 195103. Strain: atcc 13124. Gene: cpf_0184, nagh. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (164 residues) CATH domain: 2.60.120.260
2ozn
The cohesin-dockerin complex of nagj and nagh from clostridi perfringens
Source: Clostridium perfringens. Organism_taxid: 195103. Strain: atcc 13124. Gene: nagj. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Organism_taxid: 1502. Strain: strain 13. Gene: nagh.
Chain: B (131 residues) CATH domain: 1.20.1270.90
2pe4
Structure of human hyaluronidase 1, a hyaluronan hydrolyzing involved in tumor growth and angiogenesis
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hyal1, luca1. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227.
Chain: A (417 residues) CATH domain: 3.20.20.70
2w1q
Unique ligand binding specificity for a family 32 carbohydrate-binding module from the mu toxin produced by clostridium perfringens
Source: Clostridium perfringens. Organism_taxid: 1502. Atcc: 13124. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (140 residues) CATH domain: 2.60.120.260
2w1s
Unique ligand binding specificity of a family 32 carbohydrate-binding module from the mu toxin produced by clostridium perfringens
Source: Clostridium perfringens. Organism_taxid: 1502. Atcc: 13124. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (139 residues) CATH domain: 2.60.120.260
2w1u
A family 32 carbohydrate-binding module, from the mu toxin produced by clostridium perfringens, in complex with beta- d-glcnac-beta(1,3)galnac
Source: Clostridium perfringens. Organism_taxid: 1502. Atcc: 13124. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (139 residues) CATH domain: 2.60.120.260
2wdb
A family 32 carbohydrate-binding module, from the mu toxin produced by clostridium perfringens, in complex with beta- d-glcnac-beta(1,2)mannose
Source: Clostridium perfringens. Organism_taxid: 1502. Atcc: 13124. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (139 residues) CATH domain: 2.60.120.260
2wh7
The partial structure of a group a streptpcoccal phage- encoded tail fibre hyaluronate lyase hylp2
Source: Streptococcus pyogenes. Organism_taxid: 1314. Strain: m1 gas sf370. Atcc: 700294. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (152 residues) CATH domain: Unassigned